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Wipf2 Gene Detail
Summary
  • Symbol
    Wipf2
  • Name
    WAS/WASL interacting protein family, member 2
  • Synonyms
    1110014J05Rik, 5730509C05Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1924462
    NCBI Gene: 68524
  • Gene Overview
    MyGene.info: WIPF2
  • Alliance
    gene page
  • Transcription Start Sites
    5 TSS
Location &
Maps
more
  • Sequence Map
    Chr11:98863638-98905040 bp, + strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 11, 62.71 cM
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    153 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1924462
 protein coding gene Chr11:98863598-98905578 (+)
129S1/SvImJ MGP_129S1SvImJ_G0019076
 protein coding gene Chr11:101482134-101529088 (+)
A/J MGP_AJ_G0019044
 protein coding gene Chr11:97220554-97263953 (+)
AKR/J MGP_AKRJ_G0019014
 protein coding gene Chr11:100232431-100279211 (+)
BALB/cJ MGP_BALBcJ_G0019018
 protein coding gene Chr11:97717391-97758808 (+)
C3H/HeJ MGP_C3HHeJ_G0018831
 protein coding gene Chr11:100380208-100423228 (+)
C57BL/6NJ MGP_C57BL6NJ_G0019469
 protein coding gene Chr11:104580908-104632972 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0017101
 protein coding gene Chr11:94779761-94822609 (+)
CAST/EiJ MGP_CASTEiJ_G0018385
 protein coding gene Chr11:101365119-101408334 (+)
CBA/J MGP_CBAJ_G0018802
 protein coding gene Chr11:108950099-109002443 (+)
DBA/2J MGP_DBA2J_G0018910
 protein coding gene Chr11:96783792-96824899 (+)
FVB/NJ MGP_FVBNJ_G0018899
 protein coding gene Chr11:96296708-96338508 (+)
LP/J MGP_LPJ_G0018980
 protein coding gene Chr11:101935472-101982358 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0018926
 protein coding gene Chr11:108639475-108684223 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0019509
 protein coding gene Chr11:100589791-100634505 (+)
PWK/PhJ MGP_PWKPhJ_G0018156
 protein coding gene Chr11:97824619-97869555 (+)
SPRET/EiJ MGP_SPRETEiJ_G0017945
 protein coding gene Chr11:100327852-100379037 (+)
WSB/EiJ MGP_WSBEiJ_G0018434
 protein coding gene Chr11:100547294-100593163 (+)



Homology
more
  • Human Ortholog
    WIPF2, WAS/WASL interacting protein family member 2
  • Vertebrate Orthologs
    9
  • Human Ortholog
    WIPF2, WAS/WASL interacting protein family member 2
    Orthology source: HomoloGene, HGNC
  • Synonyms
    WICH, WIRE
  • Links
    NCBI Gene ID: 147179
    neXtProt AC: NX_Q8TF74
    UniProt: Q8TF74

  • Chr Location
    17q21.2; chr17:40219304-40284136 (+)  GRCh38.p7
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    12 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    15
  • GO References
    4
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    653
  • cDNA Data
    12
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000038013 Ensembl Gene Model | MGI Sequence Detail 41403 C57BL/6J ±  kb
transcript ENSMUST00000037480 Ensembl | MGI Sequence Detail 7011 Not Applicable  
polypeptide ENSMUSP00000046991 Ensembl | MGI Sequence Detail 440 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 12
    cDNA 12

    Microarray probesets 3
Other
Accession IDs
less
MGI:1915774, MGI:2143971, MGI:2686022
References
more
  • Summaries
    All 37
    Gene Ontology 4
    Phenotypes 12
  • Earliest
    J:56548 Zheng B, et al., Engineering a mouse balancer chromosome. Nat Genet. 1999 Aug;22(4):375-8
  • Latest
    J:190527 Garber JJ, et al., Enteropathogenic Escherichia coli and vaccinia virus do not require the family of WASP-interacting proteins for pathogen-induced actin assembly. Infect Immun. 2012 Dec;80(12):4071-7
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
03/03/2020
MGI 6.15 		The Jackson Laboratory