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Sobp
Gene Detail
 Symbol
Name
ID
Sobp
sine oculis-binding protein homolog (Drosophila)
MGI:1924427
Synonyms 2900009C16Rik, 5330439J01Rik, jc, Jxc1
Feature Type protein coding gene
Genetic Map
Chromosome 10
22.89 cM
Detailed Genetic Map ± 1 cM


Mapping data(4)
Sequence Map
Chr10:43002501-43174530 bp, - strand
From Ensembl annotation of GRCm38

  172030 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:41216  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 zebrafish

Gene Tree: Sobp

Human
homologs
Human Homolog SOBP, sine oculis binding protein homolog (Drosophila)
NCBI Gene ID 55084
neXtProt AC  NX_A7XYQ1
Human Synonyms  JXC1, MRAMS
Human Chr (Location)  6q21; chr6:107490113-107661309 (+)  GRCh38
Disease Associations  (1) Diseases Associated with Human SOBP
Mutations,
alleles, and
phenotypes
All mutations/alleles(4) : Spontaneous(2) Targeted(2)
Incidental mutations (data from Mutagenetix , APF )
 
Homozygous mutant mice exhibit open-field hyperactivity and circling behavior from weaning. Their hearing thresholds are elevated at all frequencies; the hearing impairment does not progress over time.
 
Interactions
Sobp interacts with 318 markers (Mir7-1, Mir7-2, Mir7b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (5 annotations)
Process inner ear morphogenesis, locomotory behavior, ...
Function metal ion binding, SUMO polymer binding
External Resources: FuncBase
Expression
Literature Summary: (2 records)
Data Summary: Results (29)    Tissues (14)   
Theiler Stages: 22, 28
Assay TypeResults
RNA in situ 29
cDNA source data(27)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(28) cDNA(28)
Microarray probesets(2)
Other database
links
Ensembl Gene ModelENSMUSG00000038248 (Evidence)
Entrez Gene109205 (Evidence)
UniGene153750
DFCITC1583412, TC1587906, TC1594893, TC1602219
DoTSDT.101132277, DT.528577, DT.55135790, DT.99844000
NIA Mouse Gene IndexU031739
Consensus CDS ProjectCCDS35890.1
International Mouse Knockout Project StatusSobp
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000038248 Ensembl Gene Model | MGI Sequence Detail 172030 C57BL/6J ±  kb
transcript ENSMUST00000040275 Ensembl | MGI Sequence Detail 4979 Not Applicable 
polypeptide ENSMUSP00000040072 Ensembl | MGI Sequence Detail 864 Not Applicable 

For the selected sequences
All sequences(33) RefSeq(6) UniProt(3)
Polymorphisms SNPs within 2kb(642 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR026092 Retinoic acid-induced protein 2/sine oculis-binding protein homolog
Protein Ontology PR:000015391 sine oculis-binding protein
References (Earliest) J:13506 Southard JL, Jackson circler, jc. Mouse News Lett. 1970;42:30
(Latest) J:197117 Sun H, et al., Poly-small ubiquitin-like modifier (PolySUMO)-binding proteins identified through a string search. J Biol Chem. 2012 Dec 7;287(50):42071-83
All references(31)
Other
accession IDs
MGD-MRK-11519, MGI:1925650, MGI:96631

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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Funding Information
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last database update
08/12/2014
MGI 5.19
The Jackson Laboratory