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Sobp
Gene Detail
Symbol

Name
ID
Sobp
sine oculis-binding protein homolog (Drosophila)
MGI:1924427
Synonyms
2900009C16Rik, 5330439J01Rik, jc, Jxc1
Feature Type
protein coding gene
Genetic Map
Chromosome 10
22.89 cM
Detailed Genetic Map ± 1 cM


Mapping data(4)
Sequence Map
Chr10:43002500-43174530 bp, - strand
From VEGA annotation of GRCm38

  172031 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:41216  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

HCOP human homology predictions: SOBP
Gene Tree: Sobp

Human
homologs
SOBP, sine oculis binding protein homolog
Orthology source: HGNC, HomoloGene

IDs:
NCBI Gene ID: 55084
neXtProt AC: NX_A7XYQ1

Human Synonyms: JXC1, MRAMS

Human Chr (Location): 6q21; chr6:107490098-107661309 (+)  GRCh38.p2

Disease Associations: (1) Diseases Associated with Human SOBP

Mutations,
alleles, and
phenotypes
All mutations/alleles(4) : Spontaneous(2) Targeted(2)
Incidental mutations (data from Mutagenetix , APF )
 
Homozygous mutant mice exhibit open-field hyperactivity and circling behavior from weaning. Their hearing thresholds are elevated at all frequencies; the hearing impairment does not progress over time.
 
Interactions
Sobp interacts with 317 markers (Mir7-1, Mir7-2, Mir7b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (5 annotations)
Process inner ear morphogenesis, locomotory behavior, ...
Function metal ion binding, SUMO polymer binding
External Resources: FuncBase
Expression
Literature Summary: (2 records)
Data Summary: Results (29)    Tissues (18)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 29
cDNA source data(27)
Other mouse links: Allen Institute   GEO   Expression Atlas
Other vertebrate links: Xenbase sobp    NEW 
Molecular
reagents
All nucleic(28) cDNA(28)
Microarray probesets(2)
Other database
links
VEGA Gene Model OTTMUSG00000046585 (Evidence)
Ensembl Gene Model ENSMUSG00000038248 (Evidence)
Entrez Gene 109205 (Evidence)
UniGene 153750
DFCI TC1583412, TC1594893, TC1587906, TC1602219
DoTS DT.55135790, DT.528577, DT.101132277, DT.99844000
NIA Mouse Gene Index U031739
Consensus CDS Project CCDS35890.1
International Mouse Phenotyping Consortium Status Sobp
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000046585 VEGA Gene Model | MGI Sequence Detail 172031 C57BL/6J ±  kb
transcript OTTMUST00000121122 VEGA | MGI Sequence Detail 4980 Not Applicable 
polypeptide OTTMUSP00000066852 VEGA | MGI Sequence Detail 864 Not Applicable 

For the selected sequences
All sequences(42) RefSeq(6) UniProt(4)
Polymorphisms
SNPs within 2kb(642 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR026092 Retinoic acid-induced protein 2/sine oculis-binding protein homolog
Protein Ontology PR:000015391 sine oculis-binding protein
References
(Earliest) J:13506 Southard JL, Jackson circler, jc. Mouse News Lett. 1970;42:30
(Latest) J:197117 Sun H, et al., Poly-small ubiquitin-like modifier (PolySUMO)-binding proteins identified through a string search. J Biol Chem. 2012 Dec 7;287(50):42071-83
All references(31)
Other
accession IDs
MGD-MRK-11519, MGI:1925650, MGI:96631

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
07/21/2015
MGI 5.22
The Jackson Laboratory