Sobp
Gene Detail

Symbol Name ID

Sobp sine oculis-binding protein homolog (Drosophila) MGI:1924427

Synonyms

2900009C16Rik, 5330439J01Rik, jc, Jxc1

Feature Type

protein coding gene

Genetic Map

Chromosome 10

22.89 cM
Detailed Genetic Map ± 1 cM


Mapping data(4)

Sequence Map

Chr10:43002501-43174530 bp, - strand From Ensembl annotation of GRCm38   172030 bp   ±  kb flank VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser

Vertebrate homology

HomoloGene:41216  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 zebrafish

Gene Tree: Sobp

Human homologs

Human Homolog		SOBP, sine oculis binding protein homolog (Drosophila)
NCBI Gene ID		55084
neXtProt AC		NX_A7XYQ1
Human Synonyms		JXC1, MRAMS
Human Chr (Location)		6q21; chr6:107811317-107982513 (+)  GRCh37.p10
Disease Associations		(1) Diseases Associated with Human SOBP

Alleles and phenotypes

All alleles(4) : Targeted(2) Spontaneous(2)
 

Homozygous mutant mice exhibit open-field hyperactivity and circling behavior from weaning. Their hearing thresholds are elevated at all frequencies; the hearing impairment does not progress over time.

 

Gene Ontology (GO) classifications

All GO classifications: (5 annotations)

Process	inner ear morphogenesis, locomotory behavior, ...
Function	metal ion binding, SUMO polymer binding

External Resources: FuncBase

Expression

Literature Summary: (2 records)
Data Summary: Results (29)    Tissues (14)   
Theiler Stages: 22, 28

Assay Type	Results
RNA in situ	29

cDNA source data(27)
External Resources: Allen Institute   GEO   ArrayExpress

Molecular reagents

All nucleic(28) cDNA(28)
Microarray probesets(2)

Other database links

Ensembl Gene Model	ENSMUSG00000038248 (Evidence)
Entrez Gene	109205 (Evidence)
UniGene	153750
DFCI	TC1583412, TC1587906, TC1594893, TC1602219
DoTS	DT.101132277, DT.528577, DT.55135790, DT.99844000
NIA Mouse Gene Index	U031739
Consensus CDS Project	CCDS35890.1
International Mouse Knockout Project Status	Sobp

Sequences

Length	Strain/Species
genomic	ENSMUSG00000038248	Ensembl Gene Model | MGI Sequence Detail	172030	C57BL/6J
transcript	ENSMUST00000040275	Ensembl | MGI Sequence Detail	4979	Not Applicable
polypeptide	ENSMUSP00000040072	Ensembl | MGI Sequence Detail	864	Not Applicable

All sequences(29) RefSeq(2) UniProt(3)

Polymorphisms

SNPs(594 from dbSNP Build 128)

Protein-related information

Resource	ID	Description
InterPro	IPR026092	Retinoic acid-induced protein 2/sine oculis-binding protein homolog
Protein Ontology	PR:000015391	sine oculis-binding protein

References

(Earliest) J:13506 Southard JL, Jackson circler, jc. Mouse News Lett. 1970;42:30
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(30)

Other accession IDs

MGD-MRK-11519, MGI:1925650, MGI:96631