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Atp6v0d2 Gene Detail
Summary
  • Symbol
    Atp6v0d2
  • Name
    ATPase, H+ transporting, lysosomal V0 subunit D2
  • Synonyms
    1620401A02Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1924415
    NCBI Gene: 242341
  • Alliance
  • Transcription Start Sites
    5 TSS
Location &
Maps
more
  • Sequence Map
    Chr4:19876838-19922566 bp, - strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 4, 7.67 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    308 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1924415
protein coding gene Chr4:19876838-19922605 (-)
129S1/SvImJ MGP_129S1SvImJ_G0028085
protein coding gene Chr4:16881556-16927093 (-)
A/J MGP_AJ_G0028043
protein coding gene Chr4:16427705-16477837 (-)
AKR/J MGP_AKRJ_G0028008
protein coding gene Chr4:16783462-16834084 (-)
BALB/cJ MGP_BALBcJ_G0028054
protein coding gene Chr4:16402755-16448567 (-)
C3H/HeJ MGP_C3HHeJ_G0027784
protein coding gene Chr4:16888360-16941469 (-)
C57BL/6NJ MGP_C57BL6NJ_G0028497
protein coding gene Chr4:17570497-17619721 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0025839
protein coding gene Chr4:15203512-15249690 (-)
CAST/EiJ MGP_CASTEiJ_G0027239
protein coding gene Chr4:16710296-16763453 (-)
CBA/J MGP_CBAJ_G0027757
protein coding gene Chr4:18078407-18127259 (-)
DBA/2J MGP_DBA2J_G0027900
protein coding gene Chr4:16240337-16290567 (-)
FVB/NJ MGP_FVBNJ_G0027866
protein coding gene Chr4:15965155-16012661 (-)
LP/J MGP_LPJ_G0028009
protein coding gene Chr4:16937452-16983376 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0027899
protein coding gene Chr4:19135657-19184045 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0028556
protein coding gene Chr4:16681128-16730227 (-)
PWK/PhJ MGP_PWKPhJ_G0026959
protein coding gene Chr4:16138766-16189165 (-)
SPRET/EiJ MGP_SPRETEiJ_G0026788
protein coding gene Chr4:16544470-16597555 (-)
WSB/EiJ MGP_WSBEiJ_G0027316
protein coding gene Chr4:16725424-16773842 (-)



Homology
more
  • Human Ortholog
    ATP6V0D2, ATPase H+ transporting V0 subunit d2
  • Vertebrate Orthologs
    9
  • Human Ortholog
    ATP6V0D2, ATPase H+ transporting V0 subunit d2
    Orthology source: HomoloGene, HGNC
  • Synonyms
    ATP6D2, VMA6
  • Links
    NCBI Gene ID: 245972
    neXtProt AC: NX_Q8N8Y2
    UniProt: Q8N8Y2

  • Chr Location
    8q21.3; chr8:86098910-86154225 (+)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    4 phenotypes from 1 allele in 1 genetic background
    6 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
Mice homozygous for a null mutation display osteopetrosis and impaired osteoclast maturation.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
  • Comparison Matrix
  • Interactions
    less
    Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 242341 NCBI Gene Model | MGI Sequence Detail 45729 C57BL/6J ±  kb
    transcript NM_175406 RefSeq | MGI Sequence Detail 2518 C57BL/6  
    polypeptide Q80SY3 UniProt | EBI | MGI Sequence Detail 350 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 23
      cDNA 22
      Primer pair 1

      Microarray probesets 4
    Other
    Accession IDs
    less
    MGI:2140238
    References
    more
    • Summaries
      All 43
      Developmental Gene Expression 6
      Gene Ontology 7
      Phenotypes 6
    • Earliest
      J:115141 Hackam DJ, et al., Host resistance to intracellular infection: mutation of natural resistance-associated macrophage protein 1 (Nramp1) impairs phagosomal acidification. J Exp Med. 1998 Jul 20;188(2):351-64
    • Latest
      J:249431 Honda K, et al., Molecular architecture underlying fluid absorption by the developing inner ear. Elife. 2017 Oct 10;6

    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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    last database update
    11/06/2018
    MGI 6.13
    The Jackson Laboratory