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Rdh10 Gene Detail
Summary
  • Symbol
    Rdh10
  • Name
    retinol dehydrogenase 10 (all-trans)
  • Synonyms
    3110069K09Rik, 4921506A21Rik, D1Ertd762e, m366Asp
  • Feature Type
    protein coding gene
  • IDs
    MGI:1924238
    NCBI Gene: 98711
Location & Maps
more
  • Sequence Map
    Chr1:16105774-16133734 bp, + strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      27961 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 1, 4.94 cM
  • Mapping Data
    4 experiments
Homology
more
  • Human Ortholog
    RDH10, retinol dehydrogenase 10 (all-trans)
  • Vertebrate Orthologs
    10
  • Human Ortholog
    RDH10, retinol dehydrogenase 10 (all-trans)
    Orthology source: HGNC, HomoloGene
  • Synonyms
    SDR16C4
  • Links
    NCBI Gene ID: 157506
    neXtProt AC: NX_Q8IZV5

  • Chr Location
    8q21.11; chr8:73294602-73325285 (+)  GRCh38.p2

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    108 phenotypes from 8 alleles in 12 genetic backgrounds
    4 images
    16 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
  • All Mutations and Alleles
    10
  • Chemically induced (ENU)
    2
  • Targeted
    8
  • Incidental Mutations
Embryos homozygous for null or hypomorphic alleles exhibit mid-gestational lethality, reduced Retinoic Acid signaling and abnormal limb, craniofacial, somite and cardiac morphology.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000025248 VEGA Gene Model | MGI Sequence Detail 27961 C57BL/6J ±  kb
transcript OTTMUST00000062152 VEGA | MGI Sequence Detail 3587 Not Applicable  
polypeptide OTTMUSP00000030597 VEGA | MGI Sequence Detail 341 Not Applicable  
For the selected sequence
Polymorphisms
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  • SNPs within 2kb
    92 from dbSNP Build 142
Protein
Information
less
Molecular
Reagents
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  • All nucleic 19
    cDNA 13
    Primer pair 3
    Other 3

    Microarray probesets 6
Other
Accession IDs
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MGI:1289239, MGI:1918069, MGI:2138371, MGI:2138606, MGI:3799292
References
more
  • Summaries
    All 52
    Developmental Gene Expression 16
    Gene Ontology 6
    Phenotypes 16
  • Earliest
    J:60984 Ko MS, et al., Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Development. 2000 Apr;127(8):1737-49
  • Latest
    J:227025 Wright DM, et al., Retinoic acid regulates embryonic development of mammalian submandibular salivary glands. Dev Biol. 2015 Nov 1;407(1):57-67

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
07/12/2016
MGI 6.04
The Jackson Laboratory