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Scfd1 Gene Detail
Summary
  • Symbol
    Scfd1
  • Name
    Sec1 family domain containing 1
  • Synonyms
    3110021P21Rik, RA410, STXBP1L2
  • Feature Type
    protein coding gene
  • IDs
    MGI:1924233
    NCBI Gene: 76983
  • Gene Overview
    MyGene.info: SCFD1
  • Alliance
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr12:51377513-51450102 bp, + strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 12, 22.11 cM, cytoband C1
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    995 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1924233
protein coding gene Chr12:51377510-51450102 (.)
129S1/SvImJ MGP_129S1SvImJ_G0019723
protein coding gene Chr12:50163602-50243355 (+)
A/J MGP_AJ_G0019685
protein coding gene Chr12:48401255-48474175 (+)
AKR/J MGP_AKRJ_G0019656
protein coding gene Chr12:49841984-49922203 (+)
BALB/cJ MGP_BALBcJ_G0019663
protein coding gene Chr12:48681718-48753702 (+)
C3H/HeJ MGP_C3HHeJ_G0019466
protein coding gene Chr12:49954751-50029108 (+)
C57BL/6NJ MGP_C57BL6NJ_G0020111
protein coding gene Chr12:51732871-51810089 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0017734
protein coding gene Chr12:46812283-46879198 (+)
CAST/EiJ MGP_CASTEiJ_G0019019
protein coding gene Chr12:44982453-45057574 (+)
CBA/J MGP_CBAJ_G0019438
protein coding gene Chr12:53502007-53573953 (+)
DBA/2J MGP_DBA2J_G0019552
protein coding gene Chr12:48258355-48331823 (+)
FVB/NJ MGP_FVBNJ_G0019541
protein coding gene Chr12:47708819-47782000 (+)
LP/J MGP_LPJ_G0019624
protein coding gene Chr12:50199086-50280083 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0019577
protein coding gene Chr12:55133490-55208706 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0020149
protein coding gene Chr12:49339807-49412915 (+)
PWK/PhJ MGP_PWKPhJ_G0018786
protein coding gene Chr12:42822251-42902401 (+)
SPRET/EiJ MGP_SPRETEiJ_G0018580
protein coding gene Chr12:43929292-44004188 (+)
WSB/EiJ MGP_WSBEiJ_G0019070
protein coding gene Chr12:49823586-49900975 (+)



Homology
more
  • Human Ortholog
    SCFD1, sec1 family domain containing 1
  • Vertebrate Orthologs
    10
  • Human Ortholog
    SCFD1, sec1 family domain containing 1
    Orthology source: HomoloGene, HGNC
  • Synonyms
    C14orf163, RA410, SLY1, SLY1P, STXBP1L2
  • Links
    NCBI Gene ID: 23256
    neXtProt AC: NX_Q8WVM8
    UniProt: Q8WVM8

  • Chr Location
    14q12; chr14:30622254-30735828 (+)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    5 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 76983 NCBI Gene Model | MGI Sequence Detail 72590 C57BL/6J ±  kb
transcript NR_157117 RefSeq | MGI Sequence Detail 3170 C57BL/6  
polypeptide Q8BRF7 UniProt | EBI | MGI Sequence Detail 639 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 81
    cDNA 81

    Microarray probesets 4
References
more
  • Summaries
    All 31
    Developmental Gene Expression 1
    Gene Ontology 5
    Phenotypes 5
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:197389 Slater LH, et al., CCT chaperonin complex is required for efficient delivery of anthrax toxin into the cytosol of host cells. Proc Natl Acad Sci U S A. 2013 Jun 11;110(24):9932-7

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/06/2018
MGI 6.13
The Jackson Laboratory