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Vxn Gene Detail
Summary
  • Symbol
    Vxn
  • Name
    vexin
  • Synonyms
    3110035E14Rik, R75066
  • Feature Type
    protein coding gene
  • IDs
    MGI:1924232
    NCBI Gene: 76982
  • Alliance
    gene page
Location & Maps
more
  • Genetic Map
    Chromosome 1, 2.08 cM
  • Mapping Data
    2 experiments
Homology
more
  • Human Ortholog
    VXN, vexin
  • Vertebrate Orthologs
    8
  • Human Ortholog
    VXN, vexin
    Orthology source: HomoloGene, HGNC
  • Synonyms
    C8orf46
  • Links
    NCBI Gene ID: 254778
    neXtProt AC: NX_Q8TAG6
    UniProt: Q8TAG6

  • Chr Location
    8q13.1; chr8:66493256-66518524 (+)  GRCh38.p7
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    6 phenotype references
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
    6
  • GO References
    2
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
    16
  • Literature Summary
    1
Interactions
less
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000022603 VEGA Gene Model | MGI Sequence Detail 25945 C57BL/6J ±  kb
transcript OTTMUST00000054142 VEGA | MGI Sequence Detail 3256 Not Applicable  
polypeptide OTTMUSP00000025798 VEGA | MGI Sequence Detail 207 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    224 from dbSNP Build 142
Protein
Information
less
  • UniProt
    1 Sequence
  • InterPro Domains
    IPR027900 Protein of unknown function DUF4648
Molecular
Reagents
less
  • All nucleic 16
    cDNA 16

    Microarray probesets 3
Other
Accession IDs
less
MGI:2138225, MGI:2138522, MGI:2138731
References
more
  • Summaries
    All 29
    Developmental Gene Expression 1
    Gene Ontology 2
    Phenotypes 6
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:259111 Moore KB, et al., C8orf46 homolog encodes a novel protein Vexin that is required for neurogenesis in Xenopus laevis. Dev Biol. 2018 May 1;437(1):27-40
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
06/12/2018
MGI 6.12 		The Jackson Laboratory