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Vxn Gene Detail
Summary
  • Symbol
    Vxn
  • Name
    vexin
  • Synonyms
    3110035E14Rik, R75066
  • Feature Type
    protein coding gene
  • IDs
    MGI:1924232
    NCBI Gene: 76982
  • Alliance
    gene page
  • Transcription Start Sites
    7 TSS
Location &
Maps
more
  • Sequence Map
    Chr1:9601267-9627142 bp, + strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 1, 2.08 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    224 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1924232
 protein coding gene Chr1:9601199-9627143 (+)
129S1/SvImJ MGP_129S1SvImJ_G0015825
 protein coding gene Chr1:6831830-6862798 (+)
A/J MGP_AJ_G0015807
 protein coding gene Chr1:6906796-6933525 (+)
AKR/J MGP_AKRJ_G0015766
 protein coding gene Chr1:6791744-6817231 (+)
BALB/cJ MGP_BALBcJ_G0015763
 protein coding gene Chr1:6648152-6674102 (+)
C3H/HeJ MGP_C3HHeJ_G0015597
 protein coding gene Chr1:6714436-6740015 (+)
C57BL/6NJ MGP_C57BL6NJ_G0016217
 protein coding gene Chr1:7169045-7197693 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0013938
 protein coding gene Chr1:5760694-5787922 (+)
CAST/EiJ MGP_CASTEiJ_G0015177
 protein coding gene Chr1:6890739-6920177 (+)
CBA/J MGP_CBAJ_G0015570
 protein coding gene Chr1:7326415-7351987 (+)
DBA/2J MGP_DBA2J_G0015669
 protein coding gene Chr1:6536424-6563069 (+)
FVB/NJ MGP_FVBNJ_G0015674
 protein coding gene Chr1:6449938-6477864 (+)
LP/J MGP_LPJ_G0015741
 protein coding gene Chr1:7056297-7085090 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0015693
 protein coding gene Chr1:7967245-7995707 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0016263
 protein coding gene Chr1:6691360-6720271 (+)
PWK/PhJ MGP_PWKPhJ_G0014961
 protein coding gene Chr1:6390572-6417934 (+)
SPRET/EiJ MGP_SPRETEiJ_G0014741
 protein coding gene Chr1:6862209-6887784 (+)
WSB/EiJ MGP_WSBEiJ_G0015241
 protein coding gene Chr1:6717618-6746178 (+)



Homology
more
  • Human Ortholog
    VXN, vexin
  • Vertebrate Orthologs
    8
  • Human Ortholog
    VXN, vexin
    Orthology source: HomoloGene, HGNC
  • Synonyms
    C8orf46
  • Links
    NCBI Gene ID: 254778
    neXtProt AC: NX_Q8TAG6
    UniProt: Q8TAG6

  • Chr Location
    8q13.1; chr8:66493256-66518524 (+)  GRCh38.p7
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    7 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    7
  • GO References
    3
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    631
  • cDNA Data
    17
  • Literature Summary
    1
  • Comparison Matrix
    Gene Expression + Phenotype
    • Interactions
    less
    Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 76982 NCBI Gene Model | MGI Sequence Detail 25876 C57BL/6J ±  kb
    transcript NM_178399 RefSeq | MGI Sequence Detail 3187 C57BL/6  
    polypeptide Q8BG31 UniProt | EBI | MGI Sequence Detail 207 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 17
      cDNA 17

      Microarray probesets 3
    Other
    Accession IDs
    less
    MGI:2138225, MGI:2138522, MGI:2138731
    References
    more
    • Summaries
      All 31
      Developmental Gene Expression 1
      Gene Ontology 3
      Phenotypes 7
    • Earliest
      J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
    • Latest
      J:259111 Moore KB, et al., C8orf46 homolog encodes a novel protein Vexin that is required for neurogenesis in Xenopus laevis. Dev Biol. 2018 May 1;437(1):27-40
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    02/16/2021
    MGI 6.16     		The Jackson Laboratory