Vxn Gene Detail

Summary

• Symbol
  Vxn
• Name
  vexin
• Synonyms
  3110035E14Rik, R75066

• Feature Type
  protein coding gene
• IDs
  MGI:1924232
  NCBI Gene: 76982
• Alliance
  gene page
• Transcription Start Sites
  7 TSS

Location &
Maps

• Sequence Map
  Chr1:9601267-9627142 bp, + strand
• From NCBI annotation of GRCm38
  

  View this region in JBrowse
  
  

• Genome Browsers
  Ensembl | UCSC | NCBI

• Genetic Map
  Chromosome 1, 2.08 cM
• Mapping Data
  2 experiments

Strain
Comparison

• SNPs within 2kb
  224 from dbSNP Build 142
• Strain Annotations
  18

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_1924232	protein coding gene	Chr1:9601199-9627143 (+)
129S1/SvImJ	MGP_129S1SvImJ_G0015825	protein coding gene	Chr1:6831830-6862798 (+)
A/J	MGP_AJ_G0015807	protein coding gene	Chr1:6906796-6933525 (+)
AKR/J	MGP_AKRJ_G0015766	protein coding gene	Chr1:6791744-6817231 (+)
BALB/cJ	MGP_BALBcJ_G0015763	protein coding gene	Chr1:6648152-6674102 (+)
C3H/HeJ	MGP_C3HHeJ_G0015597	protein coding gene	Chr1:6714436-6740015 (+)
C57BL/6NJ	MGP_C57BL6NJ_G0016217	protein coding gene	Chr1:7169045-7197693 (+)
CAROLI/EiJ	MGP_CAROLIEiJ_G0013938	protein coding gene	Chr1:5760694-5787922 (+)
CAST/EiJ	MGP_CASTEiJ_G0015177	protein coding gene	Chr1:6890739-6920177 (+)
CBA/J	MGP_CBAJ_G0015570	protein coding gene	Chr1:7326415-7351987 (+)
DBA/2J	MGP_DBA2J_G0015669	protein coding gene	Chr1:6536424-6563069 (+)
FVB/NJ	MGP_FVBNJ_G0015674	protein coding gene	Chr1:6449938-6477864 (+)
LP/J	MGP_LPJ_G0015741	protein coding gene	Chr1:7056297-7085090 (+)
NOD/ShiLtJ	MGP_NODShiLtJ_G0015693	protein coding gene	Chr1:7967245-7995707 (+)
NZO/HlLtJ	MGP_NZOHlLtJ_G0016263	protein coding gene	Chr1:6691360-6720271 (+)
PWK/PhJ	MGP_PWKPhJ_G0014961	protein coding gene	Chr1:6390572-6417934 (+)
SPRET/EiJ	MGP_SPRETEiJ_G0014741	protein coding gene	Chr1:6862209-6887784 (+)
WSB/EiJ	MGP_WSBEiJ_G0015241	protein coding gene	Chr1:6717618-6746178 (+)

Homology

• Human Ortholog
  VXN, vexin

• Vertebrate Orthologs
  8

• Human Ortholog
  VXN, vexin
  Orthology source: HomoloGene, HGNC
• Synonyms
  C8orf46
• Links
  HGNC:28498

  NCBI Gene ID: 254778

  neXtProt AC: NX_Q8TAG6

  UniProt: Q8TAG6

  
  
• Chr Location
  8q13.1; chr8:66493256-66518524 (+)  GRCh38.p7

---

• HomoloGene
  Vertebrate Homology Class 17666
  1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 dog;1 chicken;1 macaque, rhesus
  
• HCOP
  human homology predictions: VXN
• Gene Tree
  Vxn
  

Mutations,
Alleles, and
Phenotypes

• Phenotype Summary
  6 phenotype references
  

• All Mutations and Alleles
  2
• Targeted
  2
• Incidental Mutations
  Mutagenetix , APF
• Find Mice (IMSR)
  7 strains or lines available

Gene Ontology
(GO)
Classifications

• All GO Annotations
  6
• GO References
  2

• External Resources
  FuncBase

Expression

• cDNA Data
  17
• Literature Summary
  1

• Other Mouse Links
  Allen Institute
  GEO
  Expression Atlas
• Other Vertebrate Links
  Xenbase vxn

Interactions

• Vxn interacts with 287 markers (Mir1b, Mir7-1, Mir7-2, ...) View All

Sequences &
Gene Models

• All Sequences
  34
• RefSeq
  2
• UniProt
  1
• CCDS
  CCDS14813.1
• UniGene
  491098

• Ensembl
  ENSMUSG00000067879 (Evidence)
• NCBI Gene
  76982

Representative Sequences			Length	Strain/Species
genomic	76982	NCBI Gene Model | MGI Sequence Detail	25876	C57BL/6J
transcript	NM_178399	RefSeq | MGI Sequence Detail	3187	C57BL/6
polypeptide	Q8BG31	UniProt | EBI | MGI Sequence Detail	207	Not Applicable

Protein
Information

• UniProt
  1 Sequence
• InterPro Domains
  IPR040470 Vexin
  IPR027900 Vexin domain

Molecular
Reagents

• All nucleic 17

  cDNA 17

  
  

  Microarray probesets 3

Other
Accession IDs

MGI:2138225, MGI:2138522, MGI:2138731

References

• Summaries
  All 29

  Developmental Gene Expression 1

  Gene Ontology 2

  Phenotypes 6
• Earliest
  J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
• Latest
  J:259111 Moore KB, et al., C8orf46 homolog encodes a novel protein Vexin that is required for neurogenesis in Xenopus laevis. Dev Biol. 2018 May 1;437(1):27-40

TSS for Vxn:

(View these features in JBrowse)

Transcription Start Site	Location	Distance from Gene 5'-end
Tssr5900	Chr1:9601135-9601144 (+)	-127 bp
Tssr5901	Chr1:9601163-9601256 (+)	-57 bp
Tssr5902	Chr1:9601263-9601310 (+)	20 bp
Tssr5903	Chr1:9601311-9601325 (+)	51 bp
Tssr5904	Chr1:9601336-9601348 (+)	75 bp
Tssr5905	Chr1:9601456-9601487 (+)	205 bp
Tssr5906	Chr1:9601491-9601504 (+)	231 bp