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2700049A03Rik
Gene Detail
Symbol

Name
ID
2700049A03Rik
RIKEN cDNA 2700049A03 gene
MGI:1924217
Synonyms
talpid3
Feature Type
protein coding gene
Genetic Map
Chromosome 12
29.39 cM, cytoband C3
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr12:71136848-71243303 bp, + strand
From VEGA annotation of GRCm38

  106456 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:8839  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 2 zebrafish

HCOP human homology predictions: KIAA0586
Gene Tree: 2700049A03Rik

Human
homologs
KIAA0586, KIAA0586
Orthology source: HomoloGene

IDs:
NCBI Gene ID: 9786
neXtProt AC: NX_Q9BVV6

Human Synonyms: Talpid3

Human Chr (Location): 14q23.1; chr14:58427385-58548831 (+)  GRCh38.p2

Disease Associations: (1) Diseases Associated with Human KIAA0586

Mutations,
alleles, and
phenotypes
All mutations/alleles(15) : Gene trapped(11) Targeted(4)
Incidental mutations (data from Mutagenetix , APF , CvDC )
 
Mice homozygous for a null mutation die during organogenesis, lack cilia, and have randomized left-right patterning, pericardial edema, and hemorrhages.
 
Interactions
2700049A03Rik interacts with 93 markers (Mir7-1, Mir27a, Mir34a, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (11 annotations)
Process cell projection organization, cilium assembly, ...
Component centrosome, ciliary basal body, ...
Function protein binding
External Resources: FuncBase
Expression
cDNA source data(76)
Other mouse links: Allen Institute   GEO   Expression Atlas
Other vertebrate links: ZFIN si:ch211-185a18.2    NEW 
Molecular
reagents
All nucleic(76) cDNA(76)
Microarray probesets(4)
Other database
links
VEGA Gene Model OTTMUSG00000033139 (Evidence)
Ensembl Gene Model ENSMUSG00000034601 (Evidence)
Entrez Gene 76967 (Evidence)
UniGene 87290
DFCI TC1582707, TC1597773, TC1603495
DoTS DT.101386698, DT.55108589
NIA Mouse Gene Index U014051
Consensus CDS Project CCDS49081.1, CCDS49082.1
International Mouse Phenotyping Consortium Status 2700049A03Rik
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000033139 VEGA Gene Model | MGI Sequence Detail 106456 C57BL/6J ±  kb
transcript OTTMUST00000082871 VEGA | MGI Sequence Detail 5763 Not Applicable 
polypeptide OTTMUSP00000044471 VEGA | MGI Sequence Detail 1520 Not Applicable 

For the selected sequences
All sequences(56) RefSeq(14) UniProt(7)
Polymorphisms
SNPs within 2kb(434 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR029246 Protein TALPID3
References
(Earliest) J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
(Latest) J:208267 Kobayashi T, et al., The CP110-interacting proteins Talpid3 and Cep290 play overlapping and distinct roles in cilia assembly. J Cell Biol. 2014 Jan 20;204(2):215-29
All references(30)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
08/25/2015
MGI 6.0
The Jackson Laboratory