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Emsy Gene Detail
Summary
  • Symbol
    Emsy
  • Name
    EMSY, BRCA2-interacting transcriptional repressor
  • Synonyms
    2210018M11Rik, 2310016L09Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1924203
    NCBI Gene: 233545
  • Gene Overview
    MyGene.info: EMSY
Location & Maps
more
  • Sequence Map
    Chr7:98587137-98656783 bp, - strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      69647 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 7, 53.86 cM
  • Mapping Data
    2 experiments
Homology
more
  • Human Ortholog
    EMSY, EMSY, BRCA2 interacting transcriptional repressor
  • Vertebrate Orthologs
    10
  • Human Ortholog
    EMSY, EMSY, BRCA2 interacting transcriptional repressor
    Orthology source: HomoloGene
  • Synonyms
    C11orf30, GL002
  • Links
    NCBI Gene ID: 56946
    neXtProt AC: NX_Q7Z589

  • Chr Location
    11q13.5; chr11:76444928-76552899 (+)  GRCh38.p2

  • HomoloGene
    Vertebrate Homology Class 32465
    1 human;1 mouse;1 rat;1 chimpanzee;1 rhesus macaque;1 cattle;1 dog;1 chicken;1 western clawed frog;1 zebrafish
  • HCOP
    human homology predictions: EMSY
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    15 phenotype references
  • All Mutations and Alleles
    12
  • Chemically induced (other)
    1
  • Gene trapped
    10
  • Radiation induced
    1
  • Genomic Mutations
    2 involving Emsy
  • Incidental Mutations
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000058884 VEGA Gene Model | MGI Sequence Detail 69647 C57BL/6J ±  kb
transcript OTTMUST00000144524 VEGA | MGI Sequence Detail 7693 Not Applicable  
polypeptide OTTMUSP00000075335 VEGA | MGI Sequence Detail 1264 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    522 from dbSNP Build 142
Protein
Information
less
  • UniProt
    8 Sequences
  • Protein Ontology
    PR:000007067 transcriptional repressor EMSY
  • InterPro Domains
    IPR033482 BRCA2-interacting transcriptional repressor EMSY
    IPR005491 ENT domain
Molecular
Reagents
less
  • All nucleic 15
    cDNA 15

    Microarray probesets 6
Other
Accession IDs
less
MGI:1916825, MGI:2142129, MGI:2142131
References
more
  • Summaries
    All 30
    Gene Ontology 4
    Phenotypes 15
  • Earliest
    J:60984 Ko MS, et al., Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Development. 2000 Apr;127(8):1737-49
  • Latest
    J:182010 Ezell SA, et al., The protein kinase Akt1 regulates the interferon response through phosphorylation of the transcriptional repressor EMSY. Proc Natl Acad Sci U S A. 2012 Mar 6;109(10):E613-21

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
08/17/2016
MGI 6.05
The Jackson Laboratory