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Emsy Gene Detail
Summary
  • Symbol
    Emsy
  • Name
    EMSY, BRCA2-interacting transcriptional repressor
  • Synonyms
    2210018M11Rik, 2310016L09Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1924203
    NCBI Gene: 233545
  • Gene Overview
    MyGene.info: EMSY
  • Alliance
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr7:98587137-98656783 bp, - strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 7, 53.86 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    522 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1924203
protein coding gene Chr7:98587130-98659557 (-)
129S1/SvImJ MGP_129S1SvImJ_G0032541
protein coding gene Chr7:101324235-101396877 (-)
A/J MGP_AJ_G0032515
protein coding gene Chr7:98822834-98893571 (-)
AKR/J MGP_AKRJ_G0032451
protein coding gene Chr7:101173379-101242977 (-)
BALB/cJ MGP_BALBcJ_G0032526
protein coding gene Chr7:98509650-98580007 (-)
C3H/HeJ MGP_C3HHeJ_G0032241
protein coding gene Chr7:101527838-101596705 (-)
C57BL/6NJ MGP_C57BL6NJ_G0033024
protein coding gene Chr7:105243711-105321973 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0030019
protein coding gene Chr7:101256111-101324358 (-)
CAST/EiJ MGP_CASTEiJ_G0031568
protein coding gene Chr7:93053832-93125149 (-)
CBA/J MGP_CBAJ_G0032208
protein coding gene Chr7:108834124-108907991 (-)
DBA/2J MGP_DBA2J_G0032360
protein coding gene Chr7:97156388-97225372 (-)
FVB/NJ MGP_FVBNJ_G0032317
protein coding gene Chr7:96953289-97023758 (-)
LP/J MGP_LPJ_G0032449
protein coding gene Chr7:102650936-102726562 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0032349
protein coding gene Chr7:110346718-110420661 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0033046
protein coding gene Chr7:100431867-100507008 (-)
PWK/PhJ MGP_PWKPhJ_G0031286
protein coding gene Chr7:90238497-90308468 (-)
SPRET/EiJ MGP_SPRETEiJ_G0031129
protein coding gene Chr7:87725840-87798307 (-)
WSB/EiJ MGP_WSBEiJ_G0031685
protein coding gene Chr7:101101742-101177853 (-)



Homology
more
  • Human Ortholog
    EMSY, EMSY, BRCA2 interacting transcriptional repressor
  • Vertebrate Orthologs
    10
  • Human Ortholog
    EMSY, EMSY, BRCA2 interacting transcriptional repressor
    Orthology source: HomoloGene, HGNC
  • Synonyms
    C11orf30, GL002
  • Links
    NCBI Gene ID: 56946
    neXtProt AC: NX_Q7Z589
    UniProt: Q7Z589

  • Chr Location
    11q13.5; chr11:76444928-76552901 (+)  GRCh38.p7

  • HomoloGene
    Vertebrate Homology Class 32465
    1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 dog;1 chicken;1 zebrafish;1 frog, western clawed;1 macaque, rhesus
  • HCOP
    human homology predictions: EMSY
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    15 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000035401 Ensembl Gene Model | MGI Sequence Detail 69647 C57BL/6J ±  kb
transcript ENSMUST00000205276 Ensembl | MGI Sequence Detail 7693 Not Applicable  
polypeptide ENSMUSP00000145858 Ensembl | MGI Sequence Detail 1264 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 16
    cDNA 16

    Microarray probesets 6
Other
Accession IDs
less
MGI:1916825, MGI:2142129, MGI:2142131
References
more
  • Summaries
    All 39
    Gene Ontology 4
    Phenotypes 15
  • Earliest
    J:88307 Giometti CS, et al., The analysis of recessive lethal mutations in mice by using two-dimensional gel electrophoresis of liver proteins. Mutat Res. 1990 Sep;242(1):47-55
  • Latest
    J:182010 Ezell SA, et al., The protein kinase Akt1 regulates the interferon response through phosphorylation of the transcriptional repressor EMSY. Proc Natl Acad Sci U S A. 2012 Mar 6;109(10):E613-21

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/13/2018
MGI 6.13
The Jackson Laboratory