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Mnd1 Gene Detail
Summary
  • Symbol
    Mnd1
  • Name
    meiotic nuclear divisions 1
  • Synonyms
    2610034E18Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1924165
    NCBI Gene: 76915
  • Alliance
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr3:84087933-84155786 bp, - strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 3, 37.46 cM, cytoband F1
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    313 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1924165
protein coding gene Chr3:84087933-84155786 (-)
129S1/SvImJ MGP_129S1SvImJ_G0027339
protein coding gene Chr3:83985018-84054953 (-)
A/J MGP_AJ_G0027303
protein coding gene Chr3:81205191-81266732 (-)
AKR/J MGP_AKRJ_G0027269
protein coding gene Chr3:83115863-83183065 (-)
BALB/cJ MGP_BALBcJ_G0027312
protein coding gene Chr3:81272428-81339184 (-)
C3H/HeJ MGP_C3HHeJ_G0027056
protein coding gene Chr3:83430634-83498185 (-)
C57BL/6NJ MGP_C57BL6NJ_G0027758
protein coding gene Chr3:87119271-87192597 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0025111
protein coding gene Chr3:76877791-76938962 (-)
CAST/EiJ MGP_CASTEiJ_G0026503
protein coding gene Chr3:83605065-83668368 (-)
CBA/J MGP_CBAJ_G0027031
protein coding gene Chr3:90055879-90122248 (-)
DBA/2J MGP_DBA2J_G0027167
protein coding gene Chr3:80723691-80787807 (-)
FVB/NJ MGP_FVBNJ_G0027135
protein coding gene Chr3:79008162-79069588 (-)
LP/J MGP_LPJ_G0027275
protein coding gene Chr3:84963159-85029148 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0027154
protein coding gene Chr3:96418057-96489646 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0027816
protein coding gene Chr3:82916757-82982250 (-)
PWK/PhJ MGP_PWKPhJ_G0026237
protein coding gene Chr3:80492154-80552208 (-)
SPRET/EiJ MGP_SPRETEiJ_G0026053
protein coding gene Chr3:82094331-82156370 (-)
WSB/EiJ MGP_WSBEiJ_G0026581
protein coding gene Chr3:83269895-83336175 (-)



Homology
more
  • Human Ortholog
    MND1, meiotic nuclear divisions 1
  • Vertebrate Orthologs
    10
  • Human Ortholog
    MND1, meiotic nuclear divisions 1
    Orthology source: HomoloGene, HGNC
  • Synonyms
    GAJ
  • Links
    NCBI Gene ID: 84057
    neXtProt AC: NX_Q9BWT6
    UniProt: Q9BWT6

  • Chr Location
    4q31.3; chr4:153344649-153415097 (+)  GRCh38.p7

Human Diseases
less
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    3 phenotypes from 1 allele in 1 genetic background
    2 phenotypes from multigenic genotypes
    8 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
Homozygous mutants for this allele display defects in homologous chromosome synapsis and double-strand break repair.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 76915 NCBI Gene Model | MGI Sequence Detail 67854 C57BL/6J ±  kb
transcript NM_029797 RefSeq | MGI Sequence Detail 874 C57BL/6  
polypeptide Q8K396 UniProt | EBI | MGI Sequence Detail 205 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 18
    cDNA 18

    Microarray probesets 3
Other
Accession IDs
less
MGI:2145676
References
more
  • Summaries
    All 38
    Developmental Gene Expression 3
    Diseases 1
    Gene Ontology 3
    Phenotypes 8
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:231705 Zhao W, et al., Significance of ligand interactions involving Hop2-Mnd1 and the RAD51 and DMC1 recombinases in homologous DNA repair and XX ovarian dysgenesis. Nucleic Acids Res. 2015 Apr 30;43(8):4055-66

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
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last database update
10/08/2019
MGI 6.14
The Jackson Laboratory