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Lrg1 Gene Detail
Summary
  • Symbol
    Lrg1
  • Name
    leucine-rich alpha-2-glycoprotein 1
  • Synonyms
    1300008B03Rik, 2310031E04Rik, Lrhg
  • Feature Type
    protein coding gene
  • IDs
    MGI:1924155
    NCBI Gene: 76905
  • Gene Overview
    MyGene.info: LRG1
Location & Maps
more
  • Sequence Map
    Chr17:56119680-56121946 bp, - strand
  • From Ensembl annotation of GRCm38

    Mouse Genome Browser
  • Download
    Sequence
      2267 bp   ±  kb flank

  • Genome Browsers
    VEGA | Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 17, 29.17 cM, cytoband D
  • Mapping Data
    3 experiments
Homology
more
  • Human Ortholog
    LRG1, leucine rich alpha-2-glycoprotein 1
  • Vertebrate Orthologs
    10
  • Human Ortholog
    LRG1, leucine rich alpha-2-glycoprotein 1
    Orthology source: HomoloGene, HGNC
  • Synonyms
    HMFT1766, LRG
  • Links
    NCBI Gene ID: 116844
    neXtProt AC: NX_P02750

  • Chr Location
    19p13.3; chr19:4537215-4540024 (-)  GRCh38.p2
  • HomoloGene
    Vertebrate Homology Class 36468
    1 human;1 mouse;1 rat;1 chimpanzee;1 rhesus macaque;1 cattle;1 dog;1 chicken;1 zebrafish;1 frog, western clawed
  • HCOP
    human homology predictions: LRG1
  • Gene Tree
    Lrg1
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    4 phenotype references
  • All Mutations and Alleles
    3
  • Targeted
    3
  • Incidental Mutations
    APF
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    10
  • GO References
    4
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    1
  • Tissues
    1
  • cDNA Data
    152
  • Literature Summary
    1
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000037095 Ensembl Gene Model | MGI Sequence Detail 2267 C57BL/6J ±  kb
transcript ENSMUST00000041357 Ensembl | MGI Sequence Detail 1351 Not Applicable  
polypeptide ENSMUSP00000038048 Ensembl | MGI Sequence Detail 342 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    2 from dbSNP Build 142
Protein
Information
less
  • UniProt
    1 Sequence
  • InterPro Domains
    IPR000483 Cysteine-rich flanking region, C-terminal
    IPR001611 Leucine-rich repeat
    IPR032675 Leucine-rich repeat domain, L domain-like
    IPR003591 Leucine-rich repeat, typical subtype
Molecular
Reagents
less
  • All nucleic 152
    cDNA 152

    Microarray probesets 3
Other
Accession IDs
less
MGI:1916869
References
more
  • Summaries
    All 28
    Developmental Gene Expression 1
    Gene Ontology 4
    Phenotypes 4
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:204744 Wang X, et al., LRG1 promotes angiogenesis by modulating endothelial TGF-beta signalling. Nature. 2013 Jul 18;499(7458):306-11
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/27/2016
MGI 6.05 		The Jackson Laboratory