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Jade2 Gene Detail
Summary
  • Symbol
    Jade2
  • Name
    jade family PHD finger 2
  • Synonyms
    1200017K05Rik, mKIAA0239, Phf15
  • Feature Type
    protein coding gene
  • IDs
    MGI:1924151
    NCBI Gene: 76901
  • Alliance
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    Chr11:51813455-51857653 bp, - strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 11, 31.50 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    167 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1924151
protein coding gene Chr11:51813451-51859192 (-)
129S1/SvImJ MGP_129S1SvImJ_G0018277
protein coding gene Chr11:51086430-51134019 (-)
A/J MGP_AJ_G0018246
protein coding gene Chr11:49151221-49194852 (-)
AKR/J MGP_AKRJ_G0018216
protein coding gene Chr11:50703336-50743561 (-)
BALB/cJ MGP_BALBcJ_G0018217
protein coding gene Chr11:49451572-49494780 (-)
C3H/HeJ MGP_C3HHeJ_G0018028
protein coding gene Chr11:50733395-50780560 (-)
C57BL/6NJ MGP_C57BL6NJ_G0018667
protein coding gene Chr11:52621160-52665509 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0016319
protein coding gene Chr11:46706811-46751746 (-)
CAST/EiJ MGP_CASTEiJ_G0017592
protein coding gene Chr11:50726819-50775811 (-)
CBA/J MGP_CBAJ_G0018003
protein coding gene Chr11:55088553-55138170 (-)
DBA/2J MGP_DBA2J_G0018110
protein coding gene Chr11:48855779-48899545 (-)
FVB/NJ MGP_FVBNJ_G0018105
protein coding gene Chr11:48576807-48620933 (-)
LP/J MGP_LPJ_G0018186
protein coding gene Chr11:51495900-51540894 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0018128
protein coding gene Chr11:56501071-56547143 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0018710
protein coding gene Chr11:50797000-50841449 (-)
PWK/PhJ MGP_PWKPhJ_G0017368
protein coding gene Chr11:49381603-49429071 (-)
SPRET/EiJ MGP_SPRETEiJ_G0017163
protein coding gene Chr11:50531386-50574986 (-)
WSB/EiJ MGP_WSBEiJ_G0017640
protein coding gene Chr11:50442842-50488927 (-)



Homology
more
  • Human Ortholog
    JADE2, jade family PHD finger 2
  • Vertebrate Orthologs
    9
  • Human Ortholog
    JADE2, jade family PHD finger 2
    Orthology source: HomoloGene, HGNC
  • Synonyms
    JADE-2, PHF15
  • Links
    NCBI Gene ID: 23338
    neXtProt AC: NX_Q9NQC1
    UniProt: Q9NQC1

  • Chr Location
    5q31.1; chr5:134524154-134583230 (+)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    10 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000020387 Ensembl Gene Model | MGI Sequence Detail 44199 C57BL/6J ±  kb
transcript ENSMUST00000020655 Ensembl | MGI Sequence Detail 6273 Not Applicable  
polypeptide ENSMUSP00000020655 Ensembl | MGI Sequence Detail 829 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 35
    cDNA 34
    Primer pair 1

    Microarray probesets 4
Other
Accession IDs
less
MGI:2144191
References
more
  • Summaries
    All 39
    Developmental Gene Expression 3
    Gene Ontology 4
    Phenotypes 10
  • Earliest
    J:137335 Roderick TH, Chromosomal inversions in studies of mammalian mutagenesis. Genetics. 1979 May;92(1 Pt 1 Suppl):s121-6
  • Latest
    J:215624 Han X, et al., Destabilizing LSD1 by Jade-2 promotes neurogenesis: an antibraking system in neural development. Mol Cell. 2014 Aug 7;55(3):482-94

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
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last database update
10/01/2019
MGI 6.14
The Jackson Laboratory