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Golga1 Gene Detail
Summary
  • Symbol
    Golga1
  • Name
    golgi autoantigen, golgin subfamily a, 1
  • Synonyms
    0710001G09Rik, 2210418B03Rik, awag, Golgi97, golgin-97
  • Feature Type
    protein coding gene
  • IDs
    MGI:1924149
    NCBI Gene: 76899
  • Gene Overview
    MyGene.info: GOLGA1
  • Alliance
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr2:39016155-39065541 bp, - strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 2, 24.42 cM, cytoband B
  • Mapping Data
    4 experiments
Strain
Comparison
more
  • SNPs within 2kb
    161 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1924149
protein coding gene Chr2:39016155-39065581 (-)
129S1/SvImJ MGP_129S1SvImJ_G0025710
protein coding gene Chr2:37811377-37864625 (-)
A/J MGP_AJ_G0025687
protein coding gene Chr2:36266623-36318363 (-)
AKR/J MGP_AKRJ_G0025657
protein coding gene Chr2:37459289-37509426 (-)
BALB/cJ MGP_BALBcJ_G0025682
protein coding gene Chr2:36326878-36386185 (-)
C3H/HeJ MGP_C3HHeJ_G0025443
protein coding gene Chr2:37370133-37421728 (-)
C57BL/6NJ MGP_C57BL6NJ_G0026128
protein coding gene Chr2:38872122-38926990 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0023533
protein coding gene Chr2:34882415-34931313 (-)
CAST/EiJ MGP_CASTEiJ_G0024906
protein coding gene Chr2:37327190-37378663 (-)
CBA/J MGP_CBAJ_G0025422
protein coding gene Chr2:40316618-40365330 (-)
DBA/2J MGP_DBA2J_G0025554
protein coding gene Chr2:35993378-36042223 (-)
FVB/NJ MGP_FVBNJ_G0025516
protein coding gene Chr2:35857566-35911800 (-)
LP/J MGP_LPJ_G0025641
protein coding gene Chr2:37691313-37743979 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0025547
protein coding gene Chr2:39902102-39954843 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0026186
protein coding gene Chr2:37351539-37401185 (-)
PWK/PhJ MGP_PWKPhJ_G0024648
protein coding gene Chr2:35907918-35955260 (-)
SPRET/EiJ MGP_SPRETEiJ_G0024453
protein coding gene Chr2:37440245-37490482 (-)
WSB/EiJ MGP_WSBEiJ_G0024974
protein coding gene Chr2:37519622-37570304 (-)



Homology
more
  • Human Ortholog
    GOLGA1, golgin A1
  • Vertebrate Orthologs
    10
  • Human Ortholog
    GOLGA1, golgin A1
    Orthology source: HomoloGene, HGNC
  • Synonyms
    golgin-97
  • Links
    NCBI Gene ID: 2800
    neXtProt AC: NX_Q92805
    UniProt: Q92805

  • Chr Location
    9q33.3; chr9:124878294-124941114 (-)  GRCh38.p7

  • HomoloGene
    Vertebrate Homology Class 68223
    1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 dog;1 chicken;1 zebrafish;1 frog, western clawed;1 macaque, rhesus
  • HCOP
    human homology predictions: GOLGA1
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    6 phenotypes from 1 allele in 1 genetic background
    7 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
Homozygous mice exhibit tremors and limb grasping behavior at two months of age. A variable severity of hearing loss was also seen.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
  • Comparison Matrix
  • Interactions
    less
    Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000026754 Ensembl Gene Model | MGI Sequence Detail 49387 C57BL/6J ±  kb
    transcript ENSMUST00000039165 Ensembl | MGI Sequence Detail 4869 Not Applicable  
    polypeptide ENSMUSP00000037735 Ensembl | MGI Sequence Detail 758 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 60
      cDNA 60

      Microarray probesets 6
    Other
    Accession IDs
    less
    MGI:1919627, MGI:2139296, MGI:3510599
    References
    more
    • Summaries
      All 42
      Developmental Gene Expression 3
      Gene Ontology 9
      Phenotypes 7
    • Earliest
      J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
    • Latest
      J:263975 Xie Z, et al., A Golgi Lipid Signaling Pathway Controls Apical Golgi Distribution and Cell Polarity during Neurogenesis. Dev Cell. 2018 Mar 26;44(6):725-740.e4

    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
    Citing These Resources
    Funding Information
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    last database update
    11/06/2018
    MGI 6.13
    The Jackson Laboratory