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Mettl15 Gene Detail
Summary
  • Symbol
    Mettl15
  • Name
    methyltransferase like 15
  • Synonyms
    0610027B03Rik, Mett5d1
  • Feature Type
    protein coding gene
  • IDs
    MGI:1924144
    NCBI Gene: 76894
  • Alliance
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr2:109092297-109280748 bp, - strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 2, 56.52 cM
  • Mapping Data
    4 experiments
Strain
Comparison
more
  • SNPs within 2kb
    455 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1924144
protein coding gene Chr2:109092297-109281330 (-)
129S1/SvImJ MGP_129S1SvImJ_G0026238
protein coding gene Chr2:111412464-111608375 (-)
A/J MGP_AJ_G0026199
protein coding gene Chr2:106735132-106926444 (-)
AKR/J MGP_AKRJ_G0026179
protein coding gene Chr2:109730014-109945564 (-)
BALB/cJ MGP_BALBcJ_G0026208
protein coding gene Chr2:107015568-107197103 (-)
C3H/HeJ MGP_C3HHeJ_G0025958
protein coding gene Chr2:110039302-110229521 (-)
C57BL/6NJ MGP_C57BL6NJ_G0026659
protein coding gene Chr2:115033054-115250233 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0024045
protein coding gene Chr2:102352679-102530985 (-)
CAST/EiJ MGP_CASTEiJ_G0025423
protein coding gene Chr2:110515767-110720735 (-)
CBA/J MGP_CBAJ_G0025936
protein coding gene Chr2:119023979-119246299 (-)
DBA/2J MGP_DBA2J_G0026074
protein coding gene Chr2:106257935-106437842 (-)
FVB/NJ MGP_FVBNJ_G0026037
protein coding gene Chr2:105186148-105364366 (-)
LP/J MGP_LPJ_G0026177
protein coding gene Chr2:111570784-111782804 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0026061
protein coding gene Chr2:123102097-123352046 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0026713
protein coding gene Chr2:109897258-110084797 (-)
PWK/PhJ MGP_PWKPhJ_G0025158
protein coding gene Chr2:105895338-106074753 (-)
SPRET/EiJ MGP_SPRETEiJ_G0024958
protein coding gene Chr2:109113214-109315276 (-)
WSB/EiJ MGP_WSBEiJ_G0025490
protein coding gene Chr2:110643622-110847738 (-)



Homology
more
  • Human Ortholog
    METTL15, methyltransferase like 15
  • Vertebrate Orthologs
    9
  • Human Ortholog
    METTL15, methyltransferase like 15
    Orthology source: HomoloGene, HGNC
  • Synonyms
    METT5D1
  • Links
    NCBI Gene ID: 196074
    neXtProt AC: NX_A6NJ78
    UniProt: A6NJ78

  • Chr Location
    11p14.1; chr11:28108251-28527041 (+)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    7 phenotype references
  • All Mutations and Alleles
    19
  • Chemically induced (other)
    1
  • Gene trapped
    16
  • Radiation induced
    2
  • Genomic Mutations
    3 involving Mettl15
  • Incidental Mutations
    APF , CvDC
  • Find Mice (IMSR)
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000057234 Ensembl Gene Model | MGI Sequence Detail 188452 C57BL/6J ±  kb
transcript ENSMUST00000081631 Ensembl | MGI Sequence Detail 1894 Not Applicable  
polypeptide ENSMUSP00000080337 Ensembl | MGI Sequence Detail 406 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    2 Sequences
  • Protein Ontology
    PR:000031553 probable methyltransferase-like protein 15
  • EC
  • InterPro Domains
    IPR002903 Ribosomal RNA small subunit methyltransferase H
    IPR029063 S-adenosyl-L-methionine-dependent methyltransferase
    IPR023397 S-adenosyl-L-methionine-dependent methyltransferase, MraW, recognition domain superfamily
Molecular
Reagents
less
  • All nucleic 15
    cDNA 15

    Microarray probesets 5
Other
Accession IDs
less
MGI:2138875, MGI:2141137
References
more
  • Summaries
    All 32
    Gene Ontology 3
    Phenotypes 7
  • Earliest
    J:109968 Roderick TH, et al., Nineteen paracentric chromosomal inversions in mice. Genetics. 1974 Jan;76(1):109-17
  • Latest
    J:265628 Gaudet P, et al., Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief Bioinform. 2011 Sep;12(5):449-62

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
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last database update
12/03/2019
MGI 6.14
The Jackson Laboratory