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Hyls1 Gene Detail
Summary
  • Symbol
    Hyls1
  • Name
    hydrolethalus syndrome 1
  • Synonyms
    3010015K02Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1924082
    NCBI Gene: 76832
  • Gene Overview
    MyGene.info: HYLS1
Location & Maps
more
  • Sequence Map
    Chr9:35560820-35570398 bp, - strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      9579 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 9, 20.32 cM
  • Mapping Data
    1 experiment
Homology
more
  • Human Ortholog
    HYLS1, HYLS1, centriolar and ciliogenesis associated
  • Vertebrate Orthologs
    9
  • Human Ortholog
    HYLS1, HYLS1, centriolar and ciliogenesis associated
    Orthology source: HomoloGene
  • Synonyms
    HLS
  • Links
    NCBI Gene ID: 219844
    neXtProt AC: NX_Q96M11

  • Chr Location
    11q24.2; chr11:125883614-125900646 (+)  GRCh38.p2

Human Diseases
more
  • Diseases
    1 with human HYLS1 associations

Human Disease Mouse Models
       Hydrolethalus Syndrome 1; HLS1   OMIM: 236680
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    6 phenotype references
  • All Mutations and Alleles
    14
  • Gene trapped
    10
  • Targeted
    4
  • Incidental Mutations
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000030728 VEGA Gene Model | MGI Sequence Detail 9579 C57BL/6J ±  kb
transcript OTTMUST00000076069 VEGA | MGI Sequence Detail 1973 Not Applicable  
polypeptide OTTMUSP00000039979 VEGA | MGI Sequence Detail 314 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    85 from dbSNP Build 142
Protein
Information
less
  • UniProt
    2 Sequences
  • InterPro Domains
    IPR026227 Hydrolethalus syndrome protein 1
    IPR027918 Hydrolethalus syndrome protein 1, C-terminal domain
Molecular
Reagents
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  • All nucleic 8
    cDNA 6
    Primer pair 2

    Microarray probesets 2
References
more
  • Summaries
    All 23
    Developmental Gene Expression 1
    Gene Ontology 2
    Phenotypes 6
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
07/19/2016
MGI 6.04
The Jackson Laboratory