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Nubpl Gene Detail
Summary
  • Symbol
    Nubpl
  • Name
    nucleotide binding protein-like
  • Synonyms
    2410170E07Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1924076
    NCBI Gene: 76826
Location & Maps
more
  • Sequence Map
    Chr12:52097737-52312744 bp, + strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      215008 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 12, 22.11 cM, cytoband C1
  • Mapping Data
    2 experiments
Homology
more
  • Human Ortholog
    NUBPL, nucleotide binding protein like
  • Vertebrate Orthologs
    10
  • Human Ortholog
    NUBPL, nucleotide binding protein like
    Orthology source: HomoloGene, HGNC
  • Synonyms
    C14orf127, huInd1, IND1
  • Links
    NCBI Gene ID: 80224
    neXtProt AC: NX_Q8TB37

  • Chr Location
    14q12; chr14:31561385-31861224 (+)  GRCh38.p2

Human Diseases
more
  • Diseases
    1 with human NUBPL associations

Human Disease Mouse Models
       Mitochondrial Complex I Deficiency   OMIM: 252010
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    4 phenotypes from 1 allele in 1 genetic background
    6 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
  • All Mutations and Alleles
    4
  • Chemically induced (other)
    1
  • Targeted
    3
  • Genomic Mutations
    1 involving Nubpl
  • Incidental Mutations
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000032938 VEGA Gene Model | MGI Sequence Detail 215008 C57BL/6J ±  kb
transcript OTTMUST00000082106 VEGA | MGI Sequence Detail 2987 Not Applicable  
polypeptide OTTMUSP00000043994 VEGA | MGI Sequence Detail 319 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    1536 from dbSNP Build 142
Protein
Information
less
  • UniProt
    4 Sequences
  • Protein Ontology
    PR:000011478 nucleotide-binding protein-like
  • InterPro Domains
    IPR000808 Mrp, conserved site
    IPR019591 Mrp/NBP35 ATP-binding protein
    IPR027417 P-loop containing nucleoside triphosphate hydrolase
Molecular
Reagents
less
  • All nucleic 15
    cDNA 15

    Microarray probesets 3
References
more
  • Summaries
    All 25
    Gene Ontology 4
    Phenotypes 6
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
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last database update
09/20/2016
MGI 6.05
The Jackson Laboratory