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Tmem234 Gene Detail
Summary
  • Symbol
    Tmem234
  • Name
    transmembrane protein 234
  • Synonyms
    1500002D11Rik, 2510006D16Rik, 4933407D05Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1924049
    NCBI Gene: 76799
  • Alliance
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr4:129494449-129502326 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
  • Genetic Map
    Chromosome 4, 63.26 cM, cytoband D2.3
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    90 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1924049
protein coding gene Chr4:129494449-129517852 (+)
129S1/SvImJ MGP_129S1SvImJ_G0028831
protein coding gene Chr4:131538830-131561625 (+)
A/J MGP_AJ_G0028790
protein coding gene Chr4:126278279-126301098 (+)
AKR/J MGP_AKRJ_G0028743
protein coding gene Chr4:129801650-129824298 (+)
BALB/cJ MGP_BALBcJ_G0028813
protein coding gene Chr4:126885325-126908694 (+)
C3H/HeJ MGP_C3HHeJ_G0028527
protein coding gene Chr4:129854857-129877509 (+)
C57BL/6NJ MGP_C57BL6NJ_G0029255
protein coding gene Chr4:136481293-136506783 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0026527
protein coding gene Chr4:119407628-119415863 (+)
CAST/EiJ MGP_CASTEiJ_G0027959
protein coding gene Chr4:128042045-128067057 (+)
CBA/J MGP_CBAJ_G0028493
protein coding gene Chr4:139878634-139901414 (+)
DBA/2J MGP_DBA2J_G0028642
protein coding gene Chr4:126714459-126737342 (+)
FVB/NJ MGP_FVBNJ_G0028609
protein coding gene Chr4:125470906-125493797 (+)
LP/J MGP_LPJ_G0028743
protein coding gene Chr4:131819515-131842399 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0028635
protein coding gene Chr4:144684840-144707646 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0029293
protein coding gene Chr4:130170852-130193671 (+)
PWK/PhJ MGP_PWKPhJ_G0027681
protein coding gene Chr4:123316312-123322072 (+)
SPRET/EiJ MGP_SPRETEiJ_G0027507
protein coding gene Chr4:126038195-126046182 (+)
WSB/EiJ MGP_WSBEiJ_G0028040
protein coding gene Chr4:130296973-130320785 (+)



Homology
more
  • Human Ortholog
    TMEM234, transmembrane protein 234
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    TMEM234, transmembrane protein 234
  • Synonyms
    AASL548, C1orf91, dJ622L5.7, PRO1105, RP4-622L5
  • Links
    NCBI Gene ID: 56063
    neXtProt AC: NX_Q8WY98
    UniProt: Q8WY98

  • Chr Location
    1p35.2; chr1:32214472-32222359 (-)  GRCh38

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    15 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
  • All Mutations and Alleles
    32
  • Chemically induced (other)
    2
  • Gene trapped
    26
  • Radiation induced
    1
  • Targeted
    3
  • Genomic Mutations
    4 involving Tmem234
  • Find Mice (IMSR)
Homozygous mutant mice exhibited an increased median serum IgG2a response to ovalbumin challenge.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

No experimental evidence to support Biological Process annotation, following literature review. See J:73796.
Cellular Component

Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • cDNA Data
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 76799 NCBI Gene Model | MGI Sequence Detail 7878 C57BL/6J ±  kb
transcript NM_001368260 RefSeq | MGI Sequence Detail 1766 C57BL/6  
polypeptide Q8R1E7 UniProt | EBI | MGI Sequence Detail 140 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 9
    cDNA 9

    Microarray probesets 5
Other
Accession IDs
less
MGI:1916240, MGI:1921320
References
more
  • Summaries
    All 35
    Gene Ontology 1
    Phenotypes 15
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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last database update
03/12/2024
MGI 6.23
The Jackson Laboratory