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Efr3a Gene Detail
Summary
  • Symbol
    Efr3a
  • Name
    EFR3 homolog A
  • Synonyms
    A130089M23Rik, C920006C10Rik, D030063F01Rik, mKIAA0143
  • Feature Type
    protein coding gene
  • IDs
    MGI:1923990
    NCBI Gene: 76740
  • Alliance
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr15:65787034-65873816 bp, + strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 15, 29.12 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    606 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1923990
protein coding gene Chr15:65787020-65873816 (+)
129S1/SvImJ MGP_129S1SvImJ_G0021900
protein coding gene Chr15:65287415-65370912 (+)
A/J MGP_AJ_G0021859
protein coding gene Chr15:62790178-62874533 (+)
AKR/J MGP_AKRJ_G0021841
protein coding gene Chr15:64546934-64634285 (+)
BALB/cJ MGP_BALBcJ_G0021866
protein coding gene Chr15:62975721-63063290 (+)
C3H/HeJ MGP_C3HHeJ_G0021639
protein coding gene Chr15:64656022-64744458 (+)
C57BL/6NJ MGP_C57BL6NJ_G0022305
protein coding gene Chr15:67799284-67895427 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0019842
protein coding gene Chr15:59609703-59695827 (+)
CAST/EiJ MGP_CASTEiJ_G0021158
protein coding gene Chr15:65320735-65400871 (+)
CBA/J MGP_CBAJ_G0021605
protein coding gene Chr15:70110411-70194132 (+)
DBA/2J MGP_DBA2J_G0021730
protein coding gene Chr15:62590697-62676855 (+)
FVB/NJ MGP_FVBNJ_G0021712
protein coding gene Chr15:61632882-61716647 (+)
LP/J MGP_LPJ_G0021802
protein coding gene Chr15:65157893-65256197 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0021735
protein coding gene Chr15:75181972-75276697 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0022327
protein coding gene Chr15:64923999-65007758 (+)
PWK/PhJ MGP_PWKPhJ_G0020899
protein coding gene Chr15:62678065-62763431 (+)
SPRET/EiJ MGP_SPRETEiJ_G0020740
protein coding gene Chr15:64774334-64861761 (+)
WSB/EiJ MGP_WSBEiJ_G0021210
protein coding gene Chr15:64894643-64984843 (+)



Homology
more
  • Human Ortholog
    EFR3A, EFR3 homolog A
  • Vertebrate Orthologs
    9
  • Human Ortholog
    EFR3A, EFR3 homolog A
    Orthology source: HomoloGene, HGNC
  • Links
    NCBI Gene ID: 23167
    neXtProt AC: NX_Q14156
    UniProt: Q14156

  • Chr Location
    8q24.22; chr8:131904088-132013642 (+)  GRCh38.p7

Human Diseases
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  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    31 phenotype references
  • All Mutations and Alleles
    23
  • Chemically induced (other)
    3
  • Endonuclease-mediated
    1
  • Gene trapped
    14
  • Radiation induced
    2
  • Targeted
    3
  • Genomic Mutations
    5 involving Efr3a
  • Incidental Mutations
  • Find Mice (IMSR)
  • Recombinase Activity
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000015002 Ensembl Gene Model | MGI Sequence Detail 86783 C57BL/6J ±  kb
transcript ENSMUST00000211878 Ensembl | MGI Sequence Detail 2541 Not Applicable  
polypeptide ENSMUSP00000148418 Ensembl | MGI Sequence Detail 846 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 18
    cDNA 18

    Microarray probesets 7
Other
Accession IDs
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MGI:2146257, MGI:2146271, MGI:2443702
References
more
  • Summaries
    All 59
    Developmental Gene Expression 3
    Diseases 1
    Gene Ontology 5
    Phenotypes 31
  • Earliest
    J:109968 Roderick TH, et al., Nineteen paracentric chromosomal inversions in mice. Genetics. 1974 Jan;76(1):109-17
  • Latest
    J:238269 Hu H, et al., The role of Efr3a in age-related hearing loss. Neuroscience. 2017 Jan 26;341:1-8

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
03/19/2019
MGI 6.13
The Jackson Laboratory