Kansl1
Gene Detail

Symbol Name ID

Kansl1 KAT8 regulatory NSL complex subunit 1 MGI:1923969

Synonyms

1700081L11Rik, mKIAA1267

Feature Type

protein coding gene

Genetic Map

Chromosome 11

67.79 cM
Detailed Genetic Map ± 1 cM


Mapping data(3)

Sequence Map

Chr11:104333501-104468861 bp, - strand From VEGA annotation of GRCm38   135361 bp   ±  kb flank VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser

Vertebrate homology

HomoloGene:9140  Vertebrate Homology Class
1 human; 1 mouse; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 zebrafish

Gene Tree: Kansl1

Human homologs

Human Homolog		KANSL1, KAT8 regulatory NSL complex subunit 1
NCBI Gene ID		284058
neXtProt AC		NX_Q7Z3B3
Human Synonyms		CENP-36, hMSL1v1, KDVS, KIAA1267, MSL1v1, NSL1
Human Chr (Location)		17q21.31; chr17:44107282-44302740 (-)  GRCh37.p10
Disease Associations		(1) Diseases Associated with Human KANSL1

Alleles and phenotypes

All alleles(173) : Targeted(3) Gene trapped(170)

Gene Ontology (GO) classifications

All GO classifications: (10 annotations)

Process	chromatin modification, histone H4-K16 acetylation, ...
Component	histone acetyltransferase complex, MLL1 complex, ...
Function	histone acetyltransferase activity (H4-K16 specific), histone acetyltransferase activity (H4-K5 specific), ...

External Resources: FuncBase

Expression

cDNA source data(164)
External Resources: Allen Institute   GEO   ArrayExpress

Molecular reagents

All nucleic(167) Genomic(1) cDNA(166)
Microarray probesets(6)

Other database links

VEGA Gene Model	OTTMUSG00000003147 (Evidence)
Ensembl Gene Model	ENSMUSG00000018412 (Evidence)
Entrez Gene	76719 (Evidence)
UniGene	136418
DFCI	TC1574813, TC1587562, TC1595212, TC1615340, TC1630789
DoTS	DT.101380317, DT.101380318, DT.101380321, DT.102551784, DT.55279895, DT.87072343, DT.91335768, DT.91402577, DT.94344446, DT.97335594
NIA Mouse Gene Index	U033518, U373002
Consensus CDS Project	CCDS48953.1
International Mouse Knockout Project Status	Kansl1

Sequences

Length	Strain/Species
genomic	OTTMUSG00000003147	VEGA Gene Model | MGI Sequence Detail	135361	C57BL/6J
transcript	OTTMUST00000006497	VEGA | MGI Sequence Detail	5427	Not Applicable
polypeptide	OTTMUSP00000003069	VEGA | MGI Sequence Detail	1099	Not Applicable

All sequences(66) RefSeq(2) UniProt(5)

Polymorphisms

SNPs(217 from dbSNP Build 128)

Protein-related information

Resource	ID	Description
InterPro	IPR026180	KAT8 regulatory NSL complex subunit 1
Protein Ontology	PR:000031979	KAT8 regulatory NSL complex subunit 1

References

(Earliest) J:93290 Araki K, et al., Exchangeable gene trap using the Cre/mutated lox system. Cell Mol Biol (Noisy-le-grand). 1999 Jul;45(5):737-50
(Latest) J:188213 Gilley J, et al., Age-dependent axonal transport and locomotor changes and tau hypophosphorylation in a "P301L" tau knockin mouse. Neurobiol Aging. 2012 Mar;33(3):621.e1-621.e15
All references(38)