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Cpb1 Gene Detail
Summary
  • Symbol
    Cpb1
  • Name
    carboxypeptidase B1 (tissue)
  • Synonyms
    0910001A18Rik, 1810063F02Rik, 2210008M23Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1923953
    NCBI Gene: 76703
  • Alliance
  • Transcription Start Sites
    10 TSS
Location &
Maps
more
  • Sequence Map
    Chr3:20249479-20275733 bp, - strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 3, 6.29 cM
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    35 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1923953
protein coding gene Chr3:20248264-20275733 (-)
129S1/SvImJ MGP_129S1SvImJ_G0027102
protein coding gene Chr3:17485342-17513970 (-)
A/J MGP_AJ_G0027062
protein coding gene Chr3:17384508-17410828 (-)
AKR/J MGP_AKRJ_G0027031
protein coding gene Chr3:17583743-17610025 (-)
BALB/cJ MGP_BALBcJ_G0027074
protein coding gene Chr3:17129947-17156325 (-)
C3H/HeJ MGP_C3HHeJ_G0026815
protein coding gene Chr3:17588329-17615281 (-)
C57BL/6NJ MGP_C57BL6NJ_G0027519
protein coding gene Chr3:18578474-18605964 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0024881
protein coding gene Chr3:15429893-15459234 (-)
CAST/EiJ MGP_CASTEiJ_G0026270
protein coding gene Chr3:17475880-17506163 (-)
CBA/J MGP_CBAJ_G0026793
protein coding gene Chr3:18995036-19028676 (-)
DBA/2J MGP_DBA2J_G0026927
protein coding gene Chr3:16994496-17021281 (-)
FVB/NJ MGP_FVBNJ_G0026895
protein coding gene Chr3:16651631-16680089 (-)
LP/J MGP_LPJ_G0027039
protein coding gene Chr3:18118004-18144540 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0026916
protein coding gene Chr3:21041945-21074290 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0027579
protein coding gene Chr3:17346120-17384402 (-)
PWK/PhJ MGP_PWKPhJ_G0026003
protein coding gene Chr3:16716106-16718413 (-)
SPRET/EiJ MGP_SPRETEiJ_G0025811
protein coding gene Chr3:17103473-17166304 (-)
WSB/EiJ MGP_WSBEiJ_G0026343
protein coding gene Chr3:17350491-17380415 (-)



Homology
more
  • Human Ortholog
    CPB1, carboxypeptidase B1
  • Vertebrate Orthologs
    10
  • Human Ortholog
    CPB1, carboxypeptidase B1
    Orthology source: HGNC, HomoloGene
  • Synonyms
    CPB, PASP, PCPB
  • Links
    NCBI Gene ID: 1360
    neXtProt AC: NX_P15086
    UniProt: P15086

  • Chr Location
    3q24; chr3:148827801-148860187 (+)  GRCh38.p7

  • HomoloGene
    Vertebrate Homology Class 68127
    1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 dog;1 chicken;1 zebrafish;1 frog, western clawed;1 macaque, rhesus
  • HCOP
    human homology predictions: CPB1
  • Gene Tree
Human Diseases
less
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    6 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 76703 NCBI Gene Model | MGI Sequence Detail 26255 C57BL/6J ±  kb
transcript NM_029706 RefSeq | MGI Sequence Detail 1503 C57BL/6  
polypeptide NP_083982 RefSeq | MGI Sequence Detail 415 C57BL/6  
For the selected sequence
Protein
Information
less
  • UniProt
    1 Sequence
  • InterPro Domains
    IPR003146 Carboxypeptidase, activation peptide
    IPR034253 Carboxypeptidase B, carboxypeptidase domain
    IPR036990 Metallocarboxypeptidase-like, propeptide
    IPR000834 Peptidase M14, carboxypeptidase A
Molecular
Reagents
less
  • All nucleic 107
    cDNA 106
    Primer pair 1

    Microarray probesets 4
Other
Accession IDs
less
MGI:1915669, MGI:1917103, MGI:2139745
References
more
  • Summaries
    All 37
    Developmental Gene Expression 4
    Diseases 1
    Gene Ontology 4
    Phenotypes 6
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:236599 Dickinson ME, et al., High-throughput discovery of novel developmental phenotypes. Nature. 2016 Sep 14;537(7621):508-514

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
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last database update
12/04/2018
MGI 6.13
The Jackson Laboratory