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Ctrc Gene Detail
Summary
  • Symbol
    Ctrc
  • Name
    chymotrypsin C (caldecrin)
  • Synonyms
    1810044E12Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1923951
    NCBI Gene: 76701
  • Gene Overview
    MyGene.info: CTRC
Location & Maps
more
  • Sequence Map
    Chr4:141814962-141846357 bp, - strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      31396 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 4, 74.75 cM
  • Mapping Data
    1 experiment
Homology
more
  • Human Ortholog
    CTRC, chymotrypsin C
  • Vertebrate Orthologs
    10
  • Human Ortholog
    CTRC, chymotrypsin C
    Orthology source: HomoloGene, HGNC
  • Synonyms
    CLCR, ELA4
  • Links
    NCBI Gene ID: 11330
    neXtProt AC: NX_Q99895

  • Chr Location
    1p36.21; chr1:15438442-15449247 (+)  GRCh38.p2

Human Diseases
more
  • Diseases
    1 with human CTRC associations

Human Disease Mouse Models
       Pancreatitis, Hereditary; PCTT   OMIM: 167800
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    5 phenotype references
  • All Mutations and Alleles
    6
  • Chemically induced (other)
    2
  • Targeted
    4
  • Genomic Mutations
    3 involving Ctrc
  • Incidental Mutations
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
less
  • All Sequences
  • RefSeq
  • UniProt
  • UniGene
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000010017 VEGA Gene Model | MGI Sequence Detail 31396 C57BL/6J ±  kb
transcript OTTMUST00000023292 VEGA | MGI Sequence Detail 784 Not Applicable  
polypeptide OTTMUSP00000010650 VEGA | MGI Sequence Detail 235 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    827 from dbSNP Build 142
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 88
    cDNA 88

    Microarray probesets 2
References
more
  • Summaries
    All 22
    Developmental Gene Expression 1
    Gene Ontology 3
    Phenotypes 5
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:214089 Hale MA, et al., The nuclear hormone receptor family member NR5A2 controls aspects of multipotent progenitor cell formation and acinar differentiation during pancreatic organogenesis. Development. 2014 Aug;141(16):3123-33

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/29/2016
MGI 6.06
The Jackson Laboratory