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Ctrc Gene Detail
Summary
  • Symbol
    Ctrc
  • Name
    chymotrypsin C (caldecrin)
  • Synonyms
    1810044E12Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1923951
    NCBI Gene: 76701
  • Gene Overview
    MyGene.info: CTRC
  • Alliance
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr4:141838239-141846359 bp, - strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 4, 74.75 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    197 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1923951
protein coding gene Chr4:141814962-141846359 (-)
129S1/SvImJ MGP_129S1SvImJ_G0029060
protein coding gene Chr4:144919307-144951891 (-)
A/J MGP_AJ_G0029020
protein coding gene Chr4:138598891-138632637 (-)
AKR/J MGP_AKRJ_G0028972
protein coding gene Chr4:142631641-142661416 (-)
BALB/cJ MGP_BALBcJ_G0029044
protein coding gene Chr4:139289608-139319356 (-)
C3H/HeJ MGP_C3HHeJ_G0028758
protein coding gene Chr4:142987665-143019288 (-)
C57BL/6NJ MGP_C57BL6NJ_G0029485
protein coding gene Chr4:149957106-149990342 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0026755
protein coding gene Chr4:131531624-131539066 (-)
CAST/EiJ MGP_CASTEiJ_G0028190
protein coding gene Chr4:141245425-141283371 (-)
CBA/J MGP_CBAJ_G0028722
protein coding gene Chr4:154384210-154416981 (-)
DBA/2J MGP_DBA2J_G0028872
protein coding gene Chr4:138985638-139017988 (-)
FVB/NJ MGP_FVBNJ_G0028839
protein coding gene Chr4:138106612-138140764 (-)
LP/J MGP_LPJ_G0028971
protein coding gene Chr4:144923136-144956776 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0028865
protein coding gene Chr4:158105341-158140981 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0029523
protein coding gene Chr4:143152472-143183838 (-)
PWK/PhJ MGP_PWKPhJ_G0027911
protein coding gene Chr4:135884337-135916586 (-)
SPRET/EiJ MGP_SPRETEiJ_G0027735
protein coding gene Chr4:138944670-138983813 (-)
WSB/EiJ MGP_WSBEiJ_G0028268
protein coding gene Chr4:143408562-143441285 (-)



Homology
more
  • Human Ortholog
    CTRC, chymotrypsin C
  • Vertebrate Orthologs
    10
  • Human Ortholog
    CTRC, chymotrypsin C
    Orthology source: HomoloGene, HGNC
  • Synonyms
    CLCR, ELA4
  • Links
    NCBI Gene ID: 11330
    neXtProt AC: NX_Q99895
    UniProt: Q99895

  • Chr Location
    1p36.21; chr1:15438442-15449247 (+)  GRCh38.p7

Human Diseases
more
  • Diseases
    1 with human CTRC associations

Human Disease Mouse Models
      
IDs
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    7 phenotype references
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
  • All Sequences
  • RefSeq
  • UniProt
  • UniGene
Representative SequencesLengthStrain/SpeciesFlank
genomic 76701 NCBI Gene Model | MGI Sequence Detail 8121 C57BL/6J ±  kb
transcript NM_001033875 RefSeq | MGI Sequence Detail 972 Not Specified  
polypeptide Q3SYP2 UniProt | EBI | MGI Sequence Detail 268 Not Applicable  
For the selected sequence
Protein
Information
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  • UniProt
    4 Sequences
  • EC
  • InterPro Domains
    IPR001314 Peptidase S1A, chymotrypsin family
    IPR009003 Peptidase S1, PA clan
    IPR001254 Serine proteases, trypsin domain
    IPR018114 Serine proteases, trypsin family, histidine active site
    IPR033116 Serine proteases, trypsin family, serine active site
Molecular
Reagents
less
  • All nucleic 89
    cDNA 89

    Microarray probesets 2
References
more
  • Summaries
    All 26
    Developmental Gene Expression 1
    Gene Ontology 3
    Phenotypes 7
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:214089 Hale MA, et al., The nuclear hormone receptor family member NR5A2 controls aspects of multipotent progenitor cell formation and acinar differentiation during pancreatic organogenesis. Development. 2014 Aug;141(16):3123-33

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/06/2018
MGI 6.13
The Jackson Laboratory