Ctrc
Gene Detail

Symbol Name ID

Ctrc chymotrypsin C (caldecrin) MGI:1923951

Synonyms

1810044E12Rik

Feature Type

protein coding gene

Genetic Map

Chromosome 4

74.75 cM
Detailed Genetic Map ± 1 cM


Mapping data(1)

Sequence Map

Chr4:141814962-141846357 bp, - strand From VEGA annotation of GRCm38   31396 bp   ±  kb flank VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser

Vertebrate homology

HomoloGene:21422  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 2 rhesus macaque; 1 cattle; 1 dog; 1 chicken

Protein SuperFamily: trypsin
Gene Tree: Ctrc

Human homologs

Human Homolog		CTRC, chymotrypsin C (caldecrin)
NCBI Gene ID		11330
neXtProt AC		NX_Q99895
Human Synonyms		CLCR, ELA4
Human Chr (Location)		1p36.21; chr1:15764938-15773153 (+)  GRCh37.p10
Disease Associations		(1) Diseases Associated with Human CTRC

Alleles and phenotypes

All alleles(3) : Targeted(3)

Gene Ontology (GO) classifications

All GO classifications: (8 annotations)

Process	cellular calcium ion homeostasis, proteolysis
Component	cellular_component
Function	catalytic activity, hydrolase activity, ...

External Resources: FuncBase

Expression

cDNA source data(92)
External Resources: Allen Institute   GEO   ArrayExpress

Molecular reagents

All nucleic(92) cDNA(92)
Microarray probesets(2)

Other database links

VEGA Gene Model	OTTMUSG00000010017 (Evidence)
Ensembl Gene Model	ENSMUSG00000062478 (Evidence)
Entrez Gene	76701 (Evidence)
UniGene	440471
DFCI	TC1579048, TC1663096
DoTS	DT.101255316, DT.94241474
EC	3.4.21.2
International Mouse Knockout Project Status	Ctrc

Sequences

Length	Strain/Species
genomic	OTTMUSG00000010017	VEGA Gene Model | MGI Sequence Detail	31396	C57BL/6J
transcript	OTTMUST00000023292	VEGA | MGI Sequence Detail	784	Not Applicable
polypeptide	OTTMUSP00000010650	VEGA | MGI Sequence Detail	235	Not Applicable

All sequences(33) RefSeq(2) UniProt(4)

Polymorphisms

SNPs(47 from dbSNP Build 128)

Protein-related information

Resource	ID	Description
InterPro	IPR009003	Peptidase cysteine/serine, trypsin-like
InterPro	IPR001314	Peptidase S1A, chymotrypsin-type
InterPro	IPR001254	Peptidase S1/S6, chymotrypsin/Hap
InterPro	IPR018114	Peptidase S1/S6, chymotrypsin/Hap, active site
Protein Ontology	PR:000006020	chymotrypsin-C

References

(Earliest) J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
(Latest) J:80000 The FANTOM Consortium and The RIKEN Genome Exploration Research Group Phase I & II Team, Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Nature. 2002;420:563-573
All references(26)