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Mdh1b Gene Detail
Summary
  • Symbol
    Mdh1b
  • Name
    malate dehydrogenase 1B, NAD (soluble)
  • Synonyms
    1700124B08Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1923918
    NCBI Gene: 76668
  • Alliance
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr1:63698827-63730318 bp, - strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 1, 32.31 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    144 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1923918
protein coding gene Chr1:63698819-63730318 (-)
129S1/SvImJ MGP_129S1SvImJ_G0016091
protein coding gene Chr1:63869715-63901238 (-)
A/J MGP_AJ_G0016074
protein coding gene Chr1:61620322-61651839 (-)
AKR/J MGP_AKRJ_G0016031
protein coding gene Chr1:63320209-63351687 (-)
BALB/cJ MGP_BALBcJ_G0016029
protein coding gene Chr1:61695235-61726723 (-)
C3H/HeJ MGP_C3HHeJ_G0015861
protein coding gene Chr1:63622838-63654250 (-)
C57BL/6NJ MGP_C57BL6NJ_G0016482
protein coding gene Chr1:66336916-66368425 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0014203
protein coding gene Chr1:57706603-57741797 (-)
CAST/EiJ MGP_CASTEiJ_G0015444
protein coding gene Chr1:62882917-62916240 (-)
CBA/J MGP_CBAJ_G0015833
protein coding gene Chr1:68481637-68518402 (-)
DBA/2J MGP_DBA2J_G0015934
protein coding gene Chr1:61037561-61069083 (-)
FVB/NJ MGP_FVBNJ_G0015937
protein coding gene Chr1:60321255-60352669 (-)
LP/J MGP_LPJ_G0016006
protein coding gene Chr1:64760840-64792307 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0015957
protein coding gene Chr1:71403104-71434620 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0016529
protein coding gene Chr1:63317175-63348711 (-)
PWK/PhJ MGP_PWKPhJ_G0015231
protein coding gene Chr1:60406270-60441750 (-)
SPRET/EiJ MGP_SPRETEiJ_G0015010
protein coding gene Chr1:62813431-62851696 (-)
WSB/EiJ MGP_WSBEiJ_G0015506
protein coding gene Chr1:63026591-63059290 (-)



Homology
more
  • Human Ortholog
    MDH1B, malate dehydrogenase 1B
  • Vertebrate Orthologs
    10
  • Human Ortholog
    MDH1B, malate dehydrogenase 1B
    Orthology source: HomoloGene, HGNC
  • Synonyms
    RP11-95H11
  • Links
    NCBI Gene ID: 130752
    neXtProt AC: NX_Q5I0G3
    UniProt: Q5I0G3

  • Chr Location
    2q33.3; chr2:206737763-206765549 (-)  GRCh38.p7

  • HomoloGene
    Vertebrate Homology Class 57110
    1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 dog;1 chicken;1 zebrafish;1 frog, western clawed;1 macaque, rhesus
  • HCOP
    human homology predictions: MDH1B
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    7 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 76668 NCBI Gene Model | MGI Sequence Detail 31492 C57BL/6J ±  kb
transcript NM_029696 RefSeq | MGI Sequence Detail 1711 C57BL/6  
polypeptide Q5F204 UniProt | EBI | MGI Sequence Detail 500 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 5
    cDNA 5

    Microarray probesets 5
Other
Accession IDs
less
MGI:2138526
References
more
  • Summaries
    All 28
    Developmental Gene Expression 1
    Gene Ontology 3
    Phenotypes 7
  • Earliest
    J:134667 Roderick TH, et al., Two radiation-induced chromosomal inversions in mice (Mus musculus). Proc Natl Acad Sci U S A. 1970 Oct;67(2):961-7
  • Latest
    J:236179 Bowman CE, et al., Requirement for the Mitochondrial Pyruvate Carrier in Mammalian Development Revealed by a Hypomorphic Allelic Series. Mol Cell Biol. 2016 Aug 1;36(15):2089-104

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
03/19/2019
MGI 6.13
The Jackson Laboratory