About   Help   FAQ
Gtf2f1 Gene Detail
Summary
  • Symbol
    Gtf2f1
  • Name
    general transcription factor IIF, polypeptide 1
  • Synonyms
    2810405L04Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1923848
    NCBI Gene: 98053
  • Gene Overview
    MyGene.info: GTF2F1
Location & Maps
more
  • Sequence Map
    Chr17:57003405-57011288 bp, - strand
  • From Ensembl annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      7884 bp   ±  kb flank

  • Genome Browsers
Homology
more
  • Human Ortholog
    GTF2F1, general transcription factor IIF subunit 1
  • Vertebrate Orthologs
    9
  • Human Ortholog
    GTF2F1, general transcription factor IIF subunit 1
    Orthology source: HGNC, HomoloGene
  • Synonyms
    BTF4, RAP74, TF2F1, TFIIF
  • Links
    NCBI Gene ID: 2962
    neXtProt AC: NX_P35269

  • Chr Location
    19p13.3; chr19:6379569-6393280 (-)  GRCh38.p2

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    5 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000002658 Ensembl Gene Model | MGI Sequence Detail 7884 C57BL/6J ±  kb
transcript ENSMUST00000002733 Ensembl | MGI Sequence Detail 1717 Not Applicable  
polypeptide ENSMUSP00000002733 Ensembl | MGI Sequence Detail 508 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    71 from dbSNP Build 142
Protein
Information
less
  • UniProt
    3 Sequences
  • Protein Ontology
    PR:000008315 general transcription factor IIF subunit 1
  • InterPro Domains
    IPR011039 Transcription Factor IIF, Rap30/Rap74, interaction
    IPR008851 Transcription initiation factor IIF, alpha subunit
    IPR011991 Winged helix-turn-helix DNA-binding domain
Molecular
Reagents
less
  • All nucleic 96
    cDNA 96

    Microarray probesets 5
Other
Accession IDs
less
MGI:2147115
References
more
  • Summaries
    All 34
    Developmental Gene Expression 3
    Gene Ontology 5
    Phenotypes 5
  • Earliest
    J:42570 Newberry EP, et al., Structure-function analysis of Msx2-mediated transcriptional suppression. Biochemistry. 1997 Aug 26;36(34):10451-62
  • Latest
    J:181994 Kamileri I, et al., Defective transcription initiation causes postnatal growth failure in a mouse model of nucleotide excision repair (NER) progeria. Proc Natl Acad Sci U S A. 2012 Feb 21;109(8):2995-3000

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
05/17/2016
MGI 6.03
The Jackson Laboratory