Lce1i Gene Detail

Summary

• Symbol
  Lce1i
• Name
  late cornified envelope 1I
• Synonyms
  2310069N01Rik

• Feature Type
  protein coding gene
• IDs
  MGI:1923835
  NCBI Gene: 76585
• Alliance
  genome feature page
• Transcription Start Sites
  1 TSS

Location &
Maps

• Sequence Map
  Chr3:92684517-92686206 bp, - strand

  From NCBI annotation of GRCm39
  

• View this region in JBrowse
  

• Genome Browsers
  Ensembl | UCSC | NCBI

• Genetic Map
  Chromosome 3, 40.14 cM, cytoband F2
• Mapping Data
  2 experiments

Strain
Comparison

• SNPs within 2kb
  169 from dbSNP Build 142
• Strain Annotations
  19

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_1923835	protein coding gene	Chr3:92684517-92686206 (-)
129S1/SvImJ	ENSMUSG00200036876	protein coding gene	Chr3:89472123-89473812 (-)
A/J	ENSMUSG00195053126	protein coding gene	Chr3:89481439-89483128 (-)
AKR/J	ENSMUSG00220047284	protein coding gene	Chr3:88702673-88704362 (-)
BALB/cJ	ENSMUSG00180039258	protein coding gene	Chr3:89652447-89654136 (-)
C3H/HeJ	ENSMUSG00175039379	protein coding gene	Chr3:89419249-89420938 (-)
C57BL/6NJ	ENSMUSG00215048481	protein coding gene	Chr3:90031030-90032719 (-)
CAROLI/EiJ	MGP_CAROLIEiJ_G0025281	protein coding gene	Chr3:86928885-86930551 (-)
CAST/EiJ	ENSTCUG00005041231	protein coding gene	Chr3:89804917-89806543 (-)
CBA/J	ENSMUSG00210046770	protein coding gene	Chr3:89534380-89536069 (-)
DBA/2J	ENSMUSG00185048615	protein coding gene	Chr3:89736762-89738451 (-)
FVB/NJ	ENSMUSG00205046453	protein coding gene	Chr3:88528685-88530374 (-)
JF1/MsJ	ENSUMUG00000039708	protein coding gene	Chr3:89296468-89298166 (-)
LP/J	ENSMUSG00230040923	protein coding gene	Chr3:91769595-91771284 (-)
NOD/ShiLtJ	ENSMUSG00190046283	protein coding gene	Chr3:89855027-89856716 (-)
NZO/HlLtJ	ENSMUSG00225008372	protein coding gene	Chr3:94617325-94619014 (-)
PWK/PhJ	ENSLUMG00010041585	protein coding gene	Chr3:89349712-89351320 (-)
SPRET/EiJ	ENSMSPG00010048550	protein coding gene	Chr3:89807653-89809262 (-)
WSB/EiJ	ENSIUOG00005049089	protein coding gene	Chr3:90006826-90008515 (-)

Homology

• Human Ortholog
  LCE1B, late cornified envelope 1B

• Vertebrate Orthologs
  7

Vertebrate Orthology Source

Alliance of Genome Resources

• Human Ortholog
  LCE1B, late cornified envelope 1B
  
• Synonyms
  LEP2, SPRL2A
• Links
  HGNC:16611

  NCBI Gene ID: 353132

  UniProt: Q5T7P3

  
  
• Chr Location
  1q21.3; chr1:152811971-152813108 (+)  GRCh38

---

• Human Ortholog
  LCE1C, late cornified envelope 1C
  
• Synonyms
  LEP3
• Links
  HGNC:29464

  NCBI Gene ID: 353133

  UniProt: Q5T751

  
  
• Chr Location
  1q21.3; chr1:152804832-152806651 (-)  GRCh38

---

• Human Ortholog
  LCE1E, late cornified envelope 1E
  
• Synonyms
  LEP5
• Links
  HGNC:29466

  NCBI Gene ID: 353135

  UniProt: Q5T753

  
  
• Chr Location
  1q21.3; chr1:152786214-152788426 (+)  GRCh38

---

• MGI Vertebrate Homology
  Lce1i stringent orthology
  3 human;1 mouse;4 rat
  
• HCOP
  vertebrate homology predictions: LCE1B, LCE1C, LCE1E
• Gene Tree
  Lce1i
  

Human Diseases

• References
  1 with disease annotations

Mutations,
Alleles, and
Phenotypes

• Phenotype Summary
  4 phenotype references
  

• All Mutations and Alleles
  2
• Chemically induced (other)
  1
• Radiation induced
  1
• Genomic Mutations
  2 involving Lce1i
• Incidental Mutations
  APF
• Find Mice (IMSR)
  8 strains or lines available

Gene Ontology
(GO)
Classifications

• All GO Annotations
  3
• GO References
  2

Expression

• Assay Results
  597
• cDNA Data
  1

Tissue x Stage Matrix

• Other Mouse Links
  GEO
  Expression Atlas

Sequences &
Gene Models

• All Sequences
  29
• RefSeq
  2
• UniProt
  2
• CCDS
  CCDS38516.1

• Ensembl
  ENSMUSG00000068888 (Evidence)
• NCBI Gene
  76585

Representative Sequences			Length	Strain/Species
genomic	76585	NCBI Gene Model | MGI Sequence Detail	1690	C57BL/6J
transcript	NM_029667	RefSeq | MGI Sequence Detail	731	C57BL/6
polypeptide	NP_083943	RefSeq | MGI Sequence Detail	149	C57BL/6

Protein
Information

• UniProt
  2 Sequences
• InterPro Domains
  IPR028205 Late cornified envelope protein

Molecular
Reagents

• All nucleic 1

  cDNA 1

  
  

  Microarray probesets 3

References

• Summaries
  All 22

  Diseases 1

  Gene Ontology 2

  Phenotypes 4
• Earliest
  J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
• Latest
  J:302829 Lu J, et al., Mouse models for human hyperuricaemia: a critical review. Nat Rev Rheumatol. 2019 Jul;15(7):413-426

TSS for Lce1i:

(View these features in JBrowse)

Transcription Start Site	Location	Distance from Gene 5'-end
Tssr34333	Chr3:92686202-92686210 (-)	0 bp