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Tbata Gene Detail
Summary
  • Symbol
    Tbata
  • Name
    thymus, brain and testes associated
  • Synonyms
    1700021K02Rik, Spatial
  • Feature Type
    protein coding gene
  • IDs
    MGI:1923820
    NCBI Gene: 65971
  • Alliance
  • Transcription Start Sites
    12 TSS
Location &
Maps
more
  • Sequence Map
    Chr10:61171964-61188841 bp, + strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 10, 32.16 cM, cytoband B3-B4
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    66 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1923820
protein coding gene Chr10:61171954-61188841 (+)
129S1/SvImJ MGP_129S1SvImJ_G0017275
protein coding gene Chr10:60482363-60501022 (+)
A/J MGP_AJ_G0017253
protein coding gene Chr10:58684627-58701901 (+)
AKR/J MGP_AKRJ_G0017213
protein coding gene Chr10:60217522-60235243 (+)
BALB/cJ MGP_BALBcJ_G0017213
protein coding gene Chr10:58758987-58776596 (+)
C3H/HeJ MGP_C3HHeJ_G0017036
protein coding gene Chr10:60114855-60135450 (+)
C57BL/6NJ MGP_C57BL6NJ_G0017671
protein coding gene Chr10:62617043-62637264 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0015362
protein coding gene Chr10:55662674-55680542 (+)
CAST/EiJ MGP_CASTEiJ_G0016607
protein coding gene Chr10:60099500-60116931 (+)
CBA/J MGP_CBAJ_G0017008
protein coding gene Chr10:64951581-64974025 (+)
DBA/2J MGP_DBA2J_G0017113
protein coding gene Chr10:57958242-57975164 (+)
FVB/NJ MGP_FVBNJ_G0017107
protein coding gene Chr10:57214371-57231242 (+)
LP/J MGP_LPJ_G0017188
protein coding gene Chr10:60884165-60902587 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0017135
protein coding gene Chr10:67318845-67340685 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0017709
protein coding gene Chr10:60024453-60042329 (+)
PWK/PhJ MGP_PWKPhJ_G0016390
protein coding gene Chr10:57785437-57803751 (+)
SPRET/EiJ MGP_SPRETEiJ_G0016173
protein coding gene Chr10:59370046-59392169 (+)
WSB/EiJ MGP_WSBEiJ_G0016671
protein coding gene Chr10:59946026-59966048 (+)



Homology
more
  • Human Ortholog
    TBATA, thymus, brain and testes associated
  • Vertebrate Orthologs
    10
  • Human Ortholog
    TBATA, thymus, brain and testes associated
    Orthology source: HomoloGene, HGNC
  • Synonyms
    C10orf27, SPATIAL
  • Links
    NCBI Gene ID: 219793
    neXtProt AC: NX_Q96M53
    UniProt: Q96M53

  • Chr Location
    10q22.1; chr10:70771237-70785419 (-)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    8 phenotypes from 1 allele in 1 genetic background
    3 phenotypes from multigenic genotypes
    9 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
Mice homozygous for a knock-out allele exhibit increased thymic pithelial cells and total thymocyte numbers without altering T cell development and function.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
  • Comparison Matrix
  • Interactions
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    Sequences &
    Gene Models
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    Representative SequencesLengthStrain/SpeciesFlank
    genomic 65971 NCBI Gene Model | MGI Sequence Detail 16878 C57BL/6J ±  kb
    transcript NM_001017433 RefSeq | MGI Sequence Detail 1545 C57BL/6  
    polypeptide Q7TSD4 UniProt | EBI | MGI Sequence Detail 393 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    • UniProt
      9 Sequences
    • InterPro Domains
      IPR037394 Protein TBATA-like
    Molecular
    Reagents
    less
    • All nucleic 19
      cDNA 16
      Primer pair 2
      Other 1

      Microarray probesets 8
    Other
    Accession IDs
    less
    MGI:2143597
    References
    more
    • Summaries
      All 36
      Developmental Gene Expression 5
      Gene Ontology 4
      Phenotypes 9
    • Earliest
      J:109968 Roderick TH, et al., Nineteen paracentric chromosomal inversions in mice. Genetics. 1974 Jan;76(1):109-17
    • Latest
      J:166065 Flomerfelt FA, et al., Tbata modulates thymic stromal cell proliferation and thymus function. J Exp Med. 2010 Oct 25;207(11):2521-32

    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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    last database update
    03/13/2019
    MGI 6.13
    The Jackson Laboratory