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Hibch
Gene Detail
 Symbol
Name
ID
Hibch
3-hydroxyisobutyryl-Coenzyme A hydrolase
MGI:1923792
Synonyms 2610509I15Rik, HIBYL-COA-H
Feature Type protein coding gene
Genetic Map
Chromosome 1
26.99 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr1:52844929-52920986 bp, + strand
From VEGA annotation of GRCm38

  76058 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:5607  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

Gene Tree: Hibch

Human
homologs
Human Homolog HIBCH, 3-hydroxyisobutyryl-CoA hydrolase
NCBI Gene ID 26275
neXtProt AC  NX_Q6NVY1
Human Synonyms  HIBYLCOAH
Human Chr (Location)  2q32.2; chr2:190204634-190320045 (-)  GRCh38
Disease Associations  (1) Diseases Associated with Human HIBCH
Mutations,
alleles, and
phenotypes
All mutations/alleles(13) : Gene trapped(13)
Incidental mutations (data from Mutagenetix , APF )
Interactions
Hibch interacts with 120 markers (Mir7-1, Mir16-1, Mir17, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (5 annotations)
Process branched-chain amino acid catabolic process
Component extracellular vesicular exosome, mitochondrion
Function 3-hydroxyisobutyryl-CoA hydrolase activity, hydrolase activity
External Resources: FuncBase
Expression
Literature Summary: (1 records)
Data Summary: Results (94)    Tissues (94)   
Theiler Stages: 22
Assay TypeResults
RNA in situ 94
cDNA source data(42)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(42) cDNA(42)
Microarray probesets(4)
Other database
links
VEGA Gene ModelOTTMUSG00000030558 (Evidence)
Ensembl Gene ModelENSMUSG00000041426 (Evidence)
Entrez Gene227095 (Evidence)
UniGene222063
DFCITC1592240, TC1640494, TC1652152, TC1692002
DoTSDT.110920405, DT.94187835, DT.94187837
NIA Mouse Gene IndexU000270
EC3.1.2.4
Consensus CDS ProjectCCDS14948.1
International Mouse Knockout Project StatusHibch
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000030558 VEGA Gene Model | MGI Sequence Detail 76058 C57BL/6J ±  kb
transcript OTTMUST00000075675 VEGA | MGI Sequence Detail 1830 Not Applicable 
polypeptide OTTMUSP00000039724 VEGA | MGI Sequence Detail 385 Not Applicable 

For the selected sequences
All sequences(43) RefSeq(2) UniProt(2)
Polymorphisms SNPs within 2kb(627 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR014748 Crontonase, C-terminal
InterPro IPR001753 Crotonase superfamily
Protein Ontology PR:000008550 3-hydroxyisobutyryl-CoA hydrolase, mitochondrial
References (Earliest) J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
(Latest) J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
All references(33)
Other
accession IDs
MGI:2138314

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
08/19/2014
MGI 5.19
The Jackson Laboratory