Gatc Gene Detail

Summary

• Symbol
  Gatc
• Name
  glutamyl-tRNA(Gln) amidotransferase, subunit C
• Synonyms
  2010003O18Rik

• Feature Type
  protein coding gene
• IDs
  MGI:1923776
  NCBI Gene: 384281
• Alliance
  gene page

Location & Maps

• Sequence Map
  Chr5:115333239-115341178 bp, - strand
• From VEGA annotation of GRCm38
  

  Mouse Genome Browser
  
  

• Download
  Sequence
    7940 bp   ±  kb flank
  
  
• Genome Browsers
  VEGA | Ensembl | UCSC | NCBI

• Genetic Map
  Chromosome 5, 56.05 cM, cytoband F
• Mapping Data
  2 experiments

Homology

• Human Ortholog
  GATC, glutamyl-tRNA amidotransferase subunit C

• Vertebrate Orthologs
  10

• Human Ortholog
  GATC, glutamyl-tRNA amidotransferase subunit C
  Orthology source: HomoloGene, HGNC
• Synonyms
  15E1.2
• Links
  HGNC:25068

  NCBI Gene ID: 283459

  neXtProt AC: NX_O43716

  UniProt: O43716

  
  
• Chr Location
  12q24.31; chr12:120446438-120463753 (+)  GRCh38.p7

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• HomoloGene
  Vertebrate Homology Class 19922
  1 human;1 mouse;2 rat;1 chimpanzee;1 cattle;1 dog;1 chicken;1 zebrafish;1 frog, western clawed
  
• HCOP
  human homology predictions: GATC
• Gene Tree
  Gatc
  

Mutations,
Alleles, and
Phenotypes

• Phenotype Summary
  8 phenotype references
  

• All Mutations and Alleles
  4
• Chemically induced (other)
  1
• Radiation induced
  1
• Targeted
  2
• Genomic Mutations
  2 involving Gatc
• Incidental Mutations
  Mutagenetix , APF
• Find Mice (IMSR)
  7 strains or lines available

Gene Ontology
(GO)
Classifications

• All GO Annotations
  12
• GO References
  5

• External Resources
  FuncBase

Expression

• cDNA Data
  38

• Other Mouse Links
  Allen Institute
  GEO
  Expression Atlas

Interactions

• Gatc interacts with 196 markers (Mir1a-1, Mir1a-2, Mir7-1, ...) View All

Sequences &
Gene Models

• All Sequences
  15
• RefSeq
  2
• UniProt
  1
• CCDS
  CCDS19588.1
• UniGene
  229308

• VEGA
  OTTMUSG00000014655 (Evidence)
• Ensembl
  ENSMUSG00000029536 (Evidence)
• NCBI Gene
  384281

Representative Sequences			Length	Strain/Species
genomic	OTTMUSG00000014655	VEGA Gene Model | MGI Sequence Detail	7940	C57BL/6J
transcript	OTTMUST00000034760	VEGA | MGI Sequence Detail	1797	Not Applicable
polypeptide	OTTMUSP00000015556	VEGA | MGI Sequence Detail	155	Not Applicable

Polymorphisms

• SNPs within 2kb
  64 from dbSNP Build 142

Protein
Information

• UniProt
  1 Sequence
• Protein Ontology
  PR:000007864 GatC-like protein
  (term hierarchy)
• EC
  6.3.5.-
• InterPro Domains
  IPR003837 Glu-tRNAGln amidotransferase C subunit
  IPR036113 Glu-tRNAGln amidotransferase superfamily, subunit C

Molecular
Reagents

• All nucleic 39

  Genomic 1

  cDNA 38

  
  

  Microarray probesets 3

References

• Summaries
  All 32

  Gene Ontology 5

  Phenotypes 8
• Earliest
  J:134667 Roderick TH, et al., Two radiation-induced chromosomal inversions in mice (Mus musculus). Proc Natl Acad Sci U S A. 1970 Oct;67(2):961-7
• Latest
  J:212283 Echevarria L, et al., Glutamyl-tRNAGln amidotransferase is essential for mammalian mitochondrial translation in vivo. Biochem J. 2014 May 15;460(1):91-101