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Gatc Gene Detail
Summary
  • Symbol
    Gatc
  • Name
    glutamyl-tRNA(Gln) amidotransferase, subunit C
  • Synonyms
    2010003O18Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1923776
    NCBI Gene: 384281
  • Alliance
    gene page
  • Transcription Start Sites
    8 TSS
Location &
Maps
more
  • Sequence Map
    Chr5:115333242-115341161 bp, - strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 5, 56.05 cM, cytoband F
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    64 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1923776
 protein coding gene Chr5:115333239-115341178 (-)
129S1/SvImJ MGP_129S1SvImJ_G0029966
 protein coding gene Chr5:118184191-118192133 (-)
A/J MGP_AJ_G0029931
 protein coding gene Chr5:113498285-113506684 (-)
AKR/J MGP_AKRJ_G0029869
 protein coding gene Chr5:117139779-117147705 (-)
BALB/cJ MGP_BALBcJ_G0029942
 protein coding gene Chr5:114894825-114902767 (-)
C3H/HeJ MGP_C3HHeJ_G0029661
 protein coding gene Chr5:117638907-117646847 (-)
C57BL/6NJ MGP_C57BL6NJ_G0030396
 protein coding gene Chr5:122748078-122756156 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0027623
 protein coding gene Chr5:108274085-108282011 (-)
CAST/EiJ MGP_CASTEiJ_G0029070
 protein coding gene Chr5:116562423-116570253 (-)
CBA/J MGP_CBAJ_G0029629
 protein coding gene Chr5:127464257-127472191 (-)
DBA/2J MGP_DBA2J_G0029779
 protein coding gene Chr5:113572092-113580034 (-)
FVB/NJ MGP_FVBNJ_G0029735
 protein coding gene Chr5:112390319-112398253 (-)
LP/J MGP_LPJ_G0029867
 protein coding gene Chr5:118758499-118766441 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0029766
 protein coding gene Chr5:131779255-131787519 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0030437
 protein coding gene Chr5:116598967-116607220 (-)
PWK/PhJ MGP_PWKPhJ_G0028783
 protein coding gene Chr5:112234287-112242279 (-)
SPRET/EiJ MGP_SPRETEiJ_G0028621
 protein coding gene Chr5:114156479-114166916 (-)
WSB/EiJ MGP_WSBEiJ_G0029145
 protein coding gene Chr5:117197425-117205369 (-)



Homology
more
  • Human Ortholog
    GATC, glutamyl-tRNA amidotransferase subunit C
  • Vertebrate Orthologs
    10
  • Human Ortholog
    GATC, glutamyl-tRNA amidotransferase subunit C
    Orthology source: HomoloGene, HGNC
  • Synonyms
    15E1.2, COXPD42
  • Links
    NCBI Gene ID: 283459
    neXtProt AC: NX_O43716
    UniProt: O43716

  • Chr Location
    12q24.31; chr12:120446438-120463753 (+)  GRCh38.p7
Human Diseases
more
  • Diseases
    1 with human GATC associations

Human Disease Mouse Models
      
IDs
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    8 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    17
  • GO References
    6
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    631
  • cDNA Data
    38
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 384281 NCBI Gene Model | MGI Sequence Detail 7920 C57BL/6J ±  kb
transcript NM_029645 RefSeq | MGI Sequence Detail 1777 C57BL/6  
polypeptide Q8CBY0 UniProt | EBI | MGI Sequence Detail 155 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 40
    Genomic 2
    cDNA 38

    Microarray probesets 3
References
more
  • Summaries
    All 33
    Gene Ontology 6
    Phenotypes 8
  • Earliest
    J:134667 Roderick TH, et al., Two radiation-induced chromosomal inversions in mice (Mus musculus). Proc Natl Acad Sci U S A. 1970 Oct;67(2):961-7
  • Latest
    J:212283 Echevarria L, et al., Glutamyl-tRNAGln amidotransferase is essential for mammalian mitochondrial translation in vivo. Biochem J. 2014 May 15;460(1):91-101
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
03/02/2021
MGI 6.16 		The Jackson Laboratory