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Ip6k2
Gene Detail
Symbol

Name
ID
Ip6k2
inositol hexaphosphate kinase 2
MGI:1923750
Synonyms
1500005N04Rik, Ihpk2
Feature Type
protein coding gene
Genetic Map
Chromosome 9
59.63 cM, cytoband F2
Detailed Genetic Map ± 1 cM


Mapping data(3)
Sequence Map
Chr9:108783796-108806337 bp, + strand
From VEGA annotation of GRCm38

  22542 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:56929  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 2 zebrafish

Gene Tree: Ip6k2

Human
homologs
Human Homolog   IP6K2, inositol hexakisphosphate kinase 2
NCBI Gene ID 51447
neXtProt AC  NX_Q9UHH9
Human Synonyms  IHPK2, PIUS
Human Chr (Location)  3p21.31; chr3:48688003-48717278 (-)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(40) : Gene trapped(39) Targeted(1)
Incidental mutations (data from Mutagenetix , APF )
 
Mice homozygous for a knock-out allele exhibit resistance to radiation induced lethality, increased double-strand break repair, and increased incidence of chemically-induced aerodigestive tract carcinoma.
 
Interactions
Ip6k2 interacts with 88 markers (Mir1a-1, Mir1a-2, Mir7-1, ...)
Gene Ontology
(GO)
classifications
Expression
Literature Summary: (3 records)
Data Summary: Results (113)    Tissues (105)    Images (22)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 113
cDNA source data(9)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(11) cDNA(10) Primer pair(1)
Microarray probesets(10)
Other database
links
VEGA Gene ModelOTTMUSG00000050674 (Evidence)
Ensembl Gene ModelENSMUSG00000032599 (Evidence)
Entrez Gene76500 (Evidence)
DFCITC1579399, TC1595528, TC1594145, TC1583056, TC1745681, TC1627058, TC1602577, TC1736454
DoTSDT.101722724, DT.110632373, DT.94217235, DT.40138539, DT.94217224, DT.50316030, DT.101377947, DT.94217219, DT.87035329
NIA Mouse Gene IndexU011038
EC2.7.4.21
Consensus CDS ProjectCCDS23537.1
International Mouse Knockout Project StatusIp6k2
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000050674 VEGA Gene Model | MGI Sequence Detail 22542 C57BL/6J ±  kb
transcript OTTMUST00000128463 VEGA | MGI Sequence Detail 1846 Not Applicable 
polypeptide OTTMUSP00000069107 VEGA | MGI Sequence Detail 448 Not Applicable 

For the selected sequences
All sequences(107) RefSeq(16) UniProt(10)
Polymorphisms
SNPs within 2kb(72 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR005522 Inositol polyphosphate kinase
Protein Ontology PR:000009081 inositol hexakisphosphate kinase 2
References
(Earliest) J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
(Latest) J:199254 Wilson MS, et al., Inositol pyrophosphates: between signalling and metabolism. Biochem J. 2013 Jun 15;452(3):369-79
All references(37)
Other
accession IDs
MGI:2143285

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
02/25/2015
MGI 5.21
The Jackson Laboratory