Ppp1r11
Gene Detail

Symbol Name ID

Ppp1r11 protein phosphatase 1, regulatory (inhibitor) subunit 11 MGI:1923747

Synonyms

1500041B02Rik, HCGV, HCG-V, Tcte5, Tctex5, Tctex-5

Feature Type

protein coding gene

Genetic Map

Chromosome 17

19.16 cM
Detailed Genetic Map ± 1 cM


Mapping data(4)

Sequence Map

Chr17:36948356-36951741 bp, - strand From VEGA annotation of GRCm38   3386 bp   ±  kb flank VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser

Vertebrate homology

HomoloGene:32520  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 zebrafish

Gene Tree: Ppp1r11

Human homologs

Human Homolog		PPP1R11, protein phosphatase 1, regulatory (inhibitor) subunit 11
NCBI Gene ID		6992
neXtProt AC		NX_O60927
Human Synonyms		HCGV, HCG-V, IPP3, TCTE5, TCTEX5
Human Chr (Location)		6p21.3; chr6:30034932-30038110 (+)  GRCh37.p10

Alleles and phenotypes

All alleles(17) : Gene trapped(17)

Gene Ontology (GO) classifications

All GO classifications: (3 annotations)

Process	negative regulation of catalytic activity
Component	cytoplasm
Function	protein phosphatase inhibitor activity

External Resources: FuncBase

Expression

Literature Summary: (2 records)
Data Summary: Results (76)    Tissues (53)    Images (19)
Theiler Stages: 15, 19, 23, 28

Assay Type	Results
Immunohistochemistry	10
RNA in situ	29
Northern blot	12
Western blot	7
RT-PCR	18

cDNA source data(121)
External Resources: Allen Institute   GEO   ArrayExpress

Molecular reagents

All nucleic(133) Genomic(10) cDNA(121) Primer pair(2)
Microarray probesets(6)

Other database links

VEGA Gene Model	OTTMUSG00000037384 (Evidence)
Ensembl Gene Model	ENSMUSG00000036398 (Evidence)
Entrez Gene	76497 (Evidence)
UniGene	46176
DFCI	TC1575852, TC1661956
DoTS	DT.101387712, DT.94136143
Consensus CDS Project	CCDS28729.1
International Mouse Knockout Project Status	Ppp1r11

Sequences

Length	Strain/Species
genomic	OTTMUSG00000037384	VEGA Gene Model | MGI Sequence Detail	3386	C57BL/6J
transcript	OTTMUST00000096456	VEGA | MGI Sequence Detail	1599	Not Applicable
polypeptide	OTTMUSP00000053895	VEGA | MGI Sequence Detail	131	Not Applicable

All sequences(45) RefSeq(2) UniProt(6)

Polymorphisms

SNPs(17 from dbSNP Build 128)

Protein-related information

Resource	ID	Description
InterPro	IPR011107	Protein phosphatase inhibitor
Protein Ontology	PR:000013106	protein phosphatase 1 regulatory subunit 11

References

(Earliest) J:608 Ha H, et al., Several testis-expressed genes in the mouse t-complex have expression differences between wild-type and t-mutant mice. Dev Genet. 1991;12(4):318-32
(Latest) J:147466 Cheng L, et al., PP1gamma2 and PPP1R11 are parts of a multimeric complex in developing testicular germ cells in which their steady state levels are reciprocally related. PLoS ONE. 2009;4(3):e4861
All references(37)

Other accession IDs

MGD-MRK-14956, MGD-MRK-14970, MGI:2147023, MGI:98649