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Glt8d1 Gene Detail
Summary
  • Symbol
    Glt8d1
  • Name
    glycosyltransferase 8 domain containing 1
  • Synonyms
    2410004H05Rik, 5430414N14Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1923735
    NCBI Gene: 76485
  • Alliance
    gene page
  • Transcription Start Sites
    6 TSS
Location &
Maps
more
  • Sequence Map
    Chr14:31001400-31011991 bp, + strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 14, 19.09 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    16 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1923735
 protein coding gene Chr14:31001347-31012441 (+)
129S1/SvImJ MGP_129S1SvImJ_G0021115
 protein coding gene Chr14:24163286-24177379 (+)
A/J MGP_AJ_G0021063
 protein coding gene Chr14:23255942-23266148 (+)
AKR/J MGP_AKRJ_G0021040
 protein coding gene Chr14:24382360-24389522 (+)
BALB/cJ MGP_BALBcJ_G0021067
 protein coding gene Chr14:23364469-23372906 (+)
C3H/HeJ MGP_C3HHeJ_G0020850
 protein coding gene Chr14:24232015-24248258 (+)
C57BL/6NJ MGP_C57BL6NJ_G0021499
 protein coding gene Chr14:25127143-25139592 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0019062
 protein coding gene Chr14:23315053-23326276 (+)
CAST/EiJ MGP_CASTEiJ_G0020375
 protein coding gene Chr14:24004369-24017992 (+)
CBA/J MGP_CBAJ_G0020817
 protein coding gene Chr14:26095345-26109737 (+)
DBA/2J MGP_DBA2J_G0020939
 protein coding gene Chr14:23284067-23291753 (+)
FVB/NJ MGP_FVBNJ_G0020923
 protein coding gene Chr14:23236909-23252017 (+)
LP/J MGP_LPJ_G0021008
 protein coding gene Chr14:24492706-24501574 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0020949
 protein coding gene Chr14:25353153-25376238 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0021532
 protein coding gene Chr14:24134346-24145753 (+)
PWK/PhJ MGP_PWKPhJ_G0020123
 protein coding gene Chr14:22731698-22746600 (+)
SPRET/EiJ MGP_SPRETEiJ_G0019947
 protein coding gene Chr14:23725161-23736251 (+)
WSB/EiJ MGP_WSBEiJ_G0020430
 protein coding gene Chr14:24197052-24205410 (+)



Homology
more
  • Human Ortholog
    GLT8D1, glycosyltransferase 8 domain containing 1
  • Vertebrate Orthologs
    9
  • Human Ortholog
    GLT8D1, glycosyltransferase 8 domain containing 1
    Orthology source: HomoloGene, HGNC
  • Synonyms
    AD-017, MSTP139
  • Links
    NCBI Gene ID: 55830
    neXtProt AC: NX_Q68CQ7
    UniProt: Q68CQ7

  • Chr Location
    3p21.1; chr3:52694484-52706083 (-)  GRCh38.p7
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    2 phenotypes from 2 alleles in 2 genetic backgrounds
    7 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
Mice homozygous for a disruption in this gene display exhibited impaired sensorimotor gating/attention during prepulse inhibition testing.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    6
  • GO References
    3
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
    75
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000021916 Ensembl Gene Model | MGI Sequence Detail 10592 C57BL/6J ±  kb
transcript ENSMUST00000022476 Ensembl | MGI Sequence Detail 2018 Not Applicable  
polypeptide ENSMUSP00000022476 Ensembl | MGI Sequence Detail 371 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 75
    cDNA 75

    Microarray probesets 5
Other
Accession IDs
less
MGI:1918633, MGI:2145651
References
more
  • Summaries
    All 32
    Gene Ontology 3
    Phenotypes 7
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:265745 Yang CP, et al., Comprehensive integrative analyses identify GLT8D1 and CSNK2B as schizophrenia risk genes. Nat Commun. 2018 Feb 26;9(1):838
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
10/08/2019
MGI 6.14 		The Jackson Laboratory