About   Help   FAQ
Lmf1
Gene Detail
Symbol

Name
ID
Lmf1
lipase maturation factor 1
MGI:1923733
Synonyms
2400010G15Rik, cld, Tmem112
Feature Type
protein coding gene
Genetic Map
Chromosome 17
12.70 cM, cytoband A3.3
Detailed Genetic Map ± 1 cM


Mapping data(6)
Sequence Map
Chr17:25579177-25662826 bp, + strand
From VEGA annotation of GRCm38

  83650 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:23384  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

Gene Tree: Lmf1

Human
homologs
Human Homolog LMF1, lipase maturation factor 1
NCBI Gene ID 64788
neXtProt AC  NX_Q96S06
Human Synonyms  C16orf26, HMFN1876, JFP11, TMEM112, TMEM112A
Human Chr (Location)  16p13.3; chr16:853634-981318 (-)  GRCh38
Disease Associations  (1) Diseases Associated with Human LMF1
Mutations,
alleles, and
phenotypes
All mutations/alleles(5) : Gene trapped(1) Radiation induced(2) Spontaneous(1) Targeted(1)
Genomic Mutations involving Lmf1 (2)
Incidental mutations (data from Mutagenetix , APF )
 
Mutations in this gene result in death within 2 days of birth following progressive cyanosis and lipase deficiency.
 
Interactions
Lmf1 interacts with 139 markers (Mir7-1, Mir7-2, Mir7b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (18 annotations)
Process chylomicron remnant clearance, ER to Golgi vesicle-mediated transport, ...
Component cell, cytoplasm, ...
Function protein binding
External Resources: FuncBase
Expression
Literature Summary: (2 records)
Data Summary: Results (1)    Tissues (1)    Images (1)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 1
cDNA source data(13)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(13) cDNA(13)
Microarray probesets(3)
Other database
links
VEGA Gene ModelOTTMUSG00000031244 (Evidence)
Ensembl Gene ModelENSMUSG00000002279 (Evidence)
Entrez Gene76483 (Evidence)
DFCITC1576200, TC1712445, TC1591612, TC1656759, TC1596554
DoTSDT.101722616, DT.101197060, DT.101136372, DT.102558712, DT.487196, DT.99852419, DT.94385246, DT.94385179
NIA Mouse Gene IndexU017678
Consensus CDS ProjectCCDS37502.2
International Mouse Knockout Project StatusLmf1
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000031244 VEGA Gene Model | MGI Sequence Detail 83650 C57BL/6J ±  kb
transcript OTTMUST00000077396 VEGA | MGI Sequence Detail 1858 Not Applicable 
polypeptide OTTMUSP00000040925 VEGA | MGI Sequence Detail 574 Not Applicable 

For the selected sequences
All sequences(86) RefSeq(9) UniProt(13)
Polymorphisms
SNPs within 2kb(493 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR009613 Lipase maturation factor
Protein Ontology PR:000009856 lipase maturation factor 1
References
(Earliest) J:7083 Paterniti JR Jr, et al., Combined lipase deficiency (cld): a lethal mutation on chromosome 17 of the mouse. Science. 1983 Jul 8;221(4606):167-9
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(44)
Other
accession IDs
MGD-MRK-2009, MGI:2147103, MGI:88418

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
12/09/2014
MGI 5.20
The Jackson Laboratory