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Cmya5 Gene Detail
Summary
  • Symbol
    Cmya5
  • Name
    cardiomyopathy associated 5
  • Synonyms
    2310076E16Rik, 2310076E21Rik, Myospryn
  • Feature Type
    protein coding gene
  • IDs
    MGI:1923719
    NCBI Gene: 76469
  • Alliance
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr13:93040713-93144724 bp, - strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 13, 47.81 cM, cytoband C3
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    655 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1923719
protein coding gene Chr13:93040713-93144724 (-)
129S1/SvImJ MGP_129S1SvImJ_G0020822
protein coding gene Chr13:94368453-94478591 (-)
A/J MGP_AJ_G0020776
protein coding gene Chr13:90866306-90964712 (-)
AKR/J MGP_AKRJ_G0020749
protein coding gene Chr13:93618015-93731273 (-)
BALB/cJ MGP_BALBcJ_G0020772
protein coding gene Chr13:91513203-91623907 (-)
C3H/HeJ MGP_C3HHeJ_G0020566
protein coding gene Chr13:93325452-93427176 (-)
C57BL/6NJ MGP_C57BL6NJ_G0021209
protein coding gene Chr13:97245260-97360826 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0018776
protein coding gene Chr13:86774435-86869045 (-)
CAST/EiJ MGP_CASTEiJ_G0020085
protein coding gene Chr13:92592625-92692151 (-)
CBA/J MGP_CBAJ_G0020525
protein coding gene Chr13:101091596-101209088 (-)
DBA/2J MGP_DBA2J_G0020650
protein coding gene Chr13:90644280-90753933 (-)
FVB/NJ MGP_FVBNJ_G0020630
protein coding gene Chr13:89448994-89549917 (-)
LP/J MGP_LPJ_G0020723
protein coding gene Chr13:94485421-94591282 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0020659
protein coding gene Chr13:101573650-101688482 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0021249
protein coding gene Chr13:93016502-93129064 (-)
PWK/PhJ MGP_PWKPhJ_G0019837
protein coding gene Chr13:89359996-89455292 (-)
SPRET/EiJ MGP_SPRETEiJ_G0019661
protein coding gene Chr13:89300714-89399660 (-)
WSB/EiJ MGP_WSBEiJ_G0020142
protein coding gene Chr13:93513490-93619694 (-)



Homology
more
  • Human Ortholog
    CMYA5, cardiomyopathy associated 5
  • Vertebrate Orthologs
    2
  • Human Ortholog
    CMYA5, cardiomyopathy associated 5
    Orthology source: HGNC
  • Synonyms
    C5orf10, SPRYD2, TRIM76
  • Links
    NCBI Gene ID: 202333
    neXtProt AC: NX_Q8N3K9
    UniProt: Q8N3K9

  • Chr Location
    5q14.1; chr5:79689339-79800226 (+)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    4 phenotype references
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 76469 NCBI Gene Model | MGI Sequence Detail 104012 C57BL/6J ±  kb
transcript NM_023821 RefSeq | MGI Sequence Detail 11850 C57BL/6  
polypeptide Q70KF4 UniProt | EBI | MGI Sequence Detail 3739 Not Applicable  
For the selected sequence
Protein
Information
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  • UniProt
    2 Sequences
  • InterPro Domains
    IPR001870 B30.2/SPRY domain
    IPR013320 Concanavalin A-like lectin/glucanase domain superfamily
    IPR003961 Fibronectin type III
    IPR036116 Fibronectin type III superfamily
    IPR013783 Immunoglobulin-like fold
Molecular
Reagents
less
  • All nucleic 21
    cDNA 20
    Primer pair 1

    Microarray probesets 3
Other
Accession IDs
less
MGI:1919644, MGI:2145162, MGI:2145263
References
more
  • Summaries
    All 31
    Developmental Gene Expression 1
    Gene Ontology 6
    Phenotypes 4
  • Earliest
    J:182573 Roderick TH, Producing and detecting paracentric chromosomal inversions in mice. Mutat Res. 1971 Jan;11(1):59-69
  • Latest
    J:262362 Benson MA, et al., Ryanodine receptors are part of the myospryn complex in cardiac muscle. Sci Rep. 2017 Jul 24;7(1):6312

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
03/13/2019
MGI 6.13
The Jackson Laboratory