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Prss23 Gene Detail
Summary
  • Symbol
    Prss23
  • Name
    serine protease 23
  • Synonyms
    2310046G15Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1923703
    NCBI Gene: 76453
  • Alliance
    genome feature page
  • Transcription Start Sites
    15 TSS
Location &
Maps
more
  • Sequence Map
    Chr7:89156991-89176395 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 7, 49.90 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    452 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1923703
 protein coding gene Chr7:89156988-89176399 (-)
129S1/SvImJ ENSMUSG00200025943
 protein coding gene Chr7:75960952-75980366 (-)
A/J ENSMUSG00195039224
 protein coding gene Chr7:80485155-80504566 (-)
AKR/J ENSMUSG00220039548
 protein coding gene Chr7:73955461-73974872 (-)
BALB/cJ ENSMUSG00180036385
 protein coding gene Chr7:77162116-77181521 (-)
C3H/HeJ ENSMUSG00175033567
 protein coding gene Chr7:77849316-77868727 (-)
C57BL/6NJ ENSMUSG00215022557
 protein coding gene Chr7:76992600-77012005 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0029974
 protein coding gene Chr7:92639817-92649882 (-)
CAST/EiJ ENSTCUG00005045416
 protein coding gene Chr7:80465946-80485366 (-)
CBA/J ENSMUSG00210036365
 protein coding gene Chr7:77691290-77710704 (-)
DBA/2J ENSMUSG00185029596
 protein coding gene Chr7:82020848-82040262 (-)
FVB/NJ ENSMUSG00205020012
 protein coding gene Chr7:77640229-77659643 (-)
JF1/MsJ ENSUMUG00000008109
 protein coding gene Chr7:86947535-86967002 (-)
LP/J ENSMUSG00230012490
 protein coding gene Chr7:88110423-88129837 (-)
NOD/ShiLtJ ENSMUSG00190024935
 protein coding gene Chr7:77906191-77925602 (-)
NZO/HlLtJ ENSMUSG00225010744
 protein coding gene Chr7:86385104-86404517 (-)
PWK/PhJ ENSLUMG00010033109
 protein coding gene Chr7:76126230-76145655 (-)
SPRET/EiJ no annotation
WSB/EiJ ENSIUOG00005033661
 protein coding gene Chr7:78245192-78264595 (-)



Homology
more
  • Human Ortholog
    PRSS23, serine protease 23
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    PRSS23, serine protease 23
  • Synonyms
    SIG13, SPUVE, ZSIG13
  • Links
    NCBI Gene ID: 11098
    UniProt: O95084

  • Chr Location
    11q14.2; chr11:86791059-86952910 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    29 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    6
  • GO References
    5
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    698
  • Tissues
    62
  • cDNA Data
    14
  • Literature Summary
    9
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000039405 Ensembl Gene Model | MGI Sequence Detail 19405 C57BL/6J ±  kb
transcript ENSMUST00000041761 Ensembl | MGI Sequence Detail 3228 Not Applicable  
polypeptide ENSMUSP00000045191 Ensembl | MGI Sequence Detail 382 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 17
    cDNA 14
    Primer pair 2
    Other 1

    Microarray probesets 4
Other
Accession IDs
less
MGI:2142032
References
more
  • Summaries
    All 64
    Developmental Gene Expression 9
    Gene Ontology 5
    Phenotypes 29
  • Earliest
    J:141526 Russell LB, et al., Analysis of the albino-locus region of the mouse. III. Time of death of prenatal lethals. Genetics. 1979 May;92(1):205-13
  • Latest
    J:371487 Tseng CS, et al., A developmental gradient of COUP-TFI expression regulates the relative size of hippocampus dorsal and ventral subregions. PLoS Biol. 2025 Aug;23(8):e3003355
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/08/2026
MGI 6.24 		The Jackson Laboratory