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Wdr62
Gene Detail
Symbol

Name
ID
Wdr62
WD repeat domain 62
MGI:1923696
Synonyms
2310038K02Rik, MGC:31423
Feature Type
protein coding gene
Genetic Map
Chromosome 7
17.34 cM
Detailed Genetic Map ± 1 cM


Mapping data(1)
Sequence Map
Chr7:30240138-30280419 bp, - strand
From VEGA annotation of GRCm38

  40282 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:15927  Vertebrate Homology Class
1 human; 1 mouse; 2 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 western clawed frog; 1 zebrafish

HCOP human homology predictions: WDR62
Gene Tree: Wdr62

Human
homologs
WDR62, WD repeat domain 62
Orthology source: HGNC, HomoloGene

IDs:
NCBI Gene ID: 284403
neXtProt AC: NX_O43379

Human Synonyms: C19orf14, MCPH2

Human Chr (Location): 19q13.12; chr19:36054881-36105111 (+)  GRCh38.p2

Disease Associations: (1) Diseases Associated with Human WDR62

Mutations,
alleles, and
phenotypes
All mutations/alleles(11) : Gene trapped(6) Targeted(5)
Incidental mutations (data from Mutagenetix , APF , CvDC )
Interactions
Wdr62 interacts with 278 markers (Mir7-1, Mir7-2, Mir7b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (15 annotations)
Process cerebral cortex development, mitotic spindle organization, ...
Component cytoplasm, cytoskeleton, ...
Function molecular_function
External Resources: FuncBase
Expression
Literature Summary: (3 records)
Data Summary: Results (52)    Tissues (39)    Images (20)    Tissue x Stage Matrix (view)
Assay TypeResults
Immunohistochemistry 5
RNA in situ 47
cDNA source data(12)
Other mouse links: Allen Institute   GEO   Expression Atlas
Other vertebrate links: Xenbase wdr62    NEW 
Molecular
reagents
All nucleic(12) cDNA(12)
Microarray probesets(3)
Other database
links
VEGA Gene Model OTTMUSG00000024362 (Evidence)
Ensembl Gene Model ENSMUSG00000037020 (Evidence)
Entrez Gene 233064 (Evidence)
Consensus CDS Project CCDS52178.1
International Mouse Phenotyping Consortium Status Wdr62
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000024362 VEGA Gene Model | MGI Sequence Detail 40282 C57BL/6J ±  kb
transcript OTTMUST00000059683 VEGA | MGI Sequence Detail 4742 Not Applicable 
polypeptide OTTMUSP00000029050 VEGA | MGI Sequence Detail 1524 Not Applicable 

For the selected sequences
All sequences(73) RefSeq(27) UniProt(6)
Polymorphisms
SNPs within 2kb(587 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR011047 Quinonprotein alcohol dehydrogenase-like superfamily
InterPro IPR001680 WD40 repeat
InterPro IPR017986 WD40-repeat-containing domain
InterPro IPR015943 WD40/YVTN repeat-like-containing domain
InterPro IPR030545 WD repeat-containing protein 62
Protein Ontology PR:000032590 WD repeat-containing protein 62
References
(Earliest) J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
(Latest) J:206875 Xu D, et al., Microcephaly-associated protein WDR62 regulates neurogenesis through JNK1 in the developing neocortex. Cell Rep. 2014 Jan 16;6(1):104-16
All references(35)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
08/25/2015
MGI 6.0
The Jackson Laboratory