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Daam2
Gene Detail
 Symbol
Name
ID
Daam2
dishevelled associated activator of morphogenesis 2
MGI:1923691
Synonyms 2310016D11Rik
Feature Type protein coding gene
Genetic Map
Chromosome 17
25.50 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr17:49456022-49564337 bp, - strand
From NCBI annotation of GRCm38

  108316 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:69186  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken

Gene Tree: Daam2

Human
homologs
Human Homolog DAAM2, dishevelled associated activator of morphogenesis 2
NCBI Gene ID 23500
neXtProt AC  NX_Q86T65
Human Synonyms  dJ90A20A.1
Human Chr (Location)  6p21.2; chr6:39792366-39904877 (+)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(2) : Targeted(2)
Incidental mutations (data from Mutagenetix , APF )
Interactions
Daam2 interacts with 281 markers (Mir7-1, Mir7-2, Mir7b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (6 annotations)
Process actin cytoskeleton organization, cellular component organization, ...
Component cellular_component
Function actin binding, Rho GTPase binding
External Resources: FuncBase
Expression
Literature Summary: (8 records)
Data Summary: Results (310)    Tissues (146)    Images (50)
Theiler Stages: 10, 11, 12, 13, 14, 15, 17, 20, 22, 23
Assay TypeResults
RNA in situ 310
cDNA source data(12)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(13) cDNA(12) Primer pair(1)
Microarray probesets(4)
Other database
links
Ensembl Gene ModelENSMUSG00000040260 (Evidence)
Entrez Gene76441 (Evidence)
DFCITC1583545, TC1591526, TC1630794, TC1729808
DoTSDT.101250239, DT.110555493, DT.110555498, DT.55200535, DT.87039969
NIA Mouse Gene IndexU037902
Consensus CDS ProjectCCDS37648.1
International Mouse Knockout Project StatusDaam2
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic 76441 NCBI Gene Model | MGI Sequence Detail 108316 C57BL/6J ±  kb
transcript NM_001008231 RefSeq | MGI Sequence Detail 6045 C57BL/6 
polypeptide Q80U19 UniProt | EBI | MGI Sequence Detail 1115 Not Applicable 

For the selected sequences
All sequences(49) RefSeq(23) UniProt(1)
Polymorphisms SNPs within 2kb(992 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR015425 Actin-binding FH2
InterPro IPR016024 Armadillo-type fold
InterPro IPR014767 Diaphanous autoregulatory
InterPro IPR010472 Diaphanous FH3
InterPro IPR010473 Diaphanous GTPase-binding
InterPro IPR014768 GTPase-binding/formin homology 3
Protein Ontology PR:000006257 disheveled-associated activator of morphogenesis 2
Graphical View of Protein Domain Structure
References (Earliest) J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
(Latest) J:205051 Miller JA, et al., Conserved molecular signatures of neurogenesis in the hippocampal subgranular zone of rodents and primates. Development. 2013 Nov;140(22):4633-44
All references(38)
Other
accession IDs
MGI:2146931, MGI:2147093

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
09/09/2014
MGI 5.19
The Jackson Laboratory