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Daam2
Gene Detail
Symbol

Name
ID
Daam2
dishevelled associated activator of morphogenesis 2
MGI:1923691
Synonyms
2310016D11Rik
Feature Type
protein coding gene
Genetic Map
Chromosome 17
25.50 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr17:49456022-49564337 bp, - strand
From Ensembl annotation of GRCm38

  108316 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:69186  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken

Gene Tree: Daam2

Human
homologs
Human Homolog DAAM2, dishevelled associated activator of morphogenesis 2
NCBI Gene ID 23500
neXtProt AC  NX_Q86T65
Human Synonyms  dJ90A20A.1
Human Chr (Location)  6p21.2; chr6:39792366-39904877 (+)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(2) : Targeted(2)
Incidental mutations (data from Mutagenetix , APF )
Interactions
Daam2 interacts with 281 markers (Mir7-1, Mir7-2, Mir7b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (6 annotations)
Process actin cytoskeleton organization, cellular component organization, ...
Component extracellular vesicular exosome
Function actin binding, Rho GTPase binding
External Resources: FuncBase
Expression
Literature Summary: (9 records)
Data Summary: Results (310)    Tissues (146)    Images (50)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 310
cDNA source data(12)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(13) cDNA(12) Primer pair(1)
Microarray probesets(4)
Other database
links
Ensembl Gene ModelENSMUSG00000040260 (Evidence)
Entrez Gene76441 (Evidence)
DFCITC1591526, TC1583545, TC1729808, TC1630794
DoTSDT.87039969, DT.55200535, DT.101250239, DT.110555498, DT.110555493
NIA Mouse Gene IndexU037902
Consensus CDS ProjectCCDS37648.1
International Mouse Knockout Project StatusDaam2
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000040260 Ensembl Gene Model | MGI Sequence Detail 108316 C57BL/6J ±  kb
transcript ENSMUST00000057610 Ensembl | MGI Sequence Detail 6045 Not Applicable 
polypeptide ENSMUSP00000052085 Ensembl | MGI Sequence Detail 1115 Not Applicable 

For the selected sequences
All sequences(49) RefSeq(23) UniProt(1)
Polymorphisms
SNPs within 2kb(992 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR015425 Actin-binding FH2
InterPro IPR016024 Armadillo-type fold
InterPro IPR014767 Diaphanous autoregulatory
InterPro IPR010472 Diaphanous FH3
InterPro IPR010473 Diaphanous GTPase-binding
InterPro IPR014768 GTPase-binding/formin homology 3
Protein Ontology PR:000006257 disheveled-associated activator of morphogenesis 2
References
(Earliest) J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
(Latest) J:211696 Goggolidou P, et al., Atmin mediates kidney morphogenesis by modulating Wnt signaling. Hum Mol Genet. 2014 May 22;
All references(39)
Other
accession IDs
MGI:2146931, MGI:2147093

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/18/2014
MGI 5.20
The Jackson Laboratory