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Daam2
Gene Detail
Symbol

Name
ID
Daam2
dishevelled associated activator of morphogenesis 2
MGI:1923691
Synonyms
2310016D11Rik
Feature Type
protein coding gene
Genetic Map
Chromosome 17
25.50 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr17:49456022-49564337 bp, - strand
From Ensembl annotation of GRCm38

  108316 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:69186  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken

HCOP human homology predictions: DAAM2
Gene Tree: Daam2

Human
homologs
DAAM2, dishevelled associated activator of morphogenesis 2
Orthology source: HomoloGene

IDs:
NCBI Gene ID: 23500
neXtProt AC: NX_Q86T65

Human Synonyms: dJ90A20A.1

Human Chr (Location): 6p21.2; chr6:39792366-39904877 (+)  GRCh38.p2

Mutations,
alleles, and
phenotypes
All mutations/alleles(3) : Targeted(3)
Incidental mutations (data from Mutagenetix , APF , CvDC )
Interactions
Daam2 interacts with 280 markers (Mir7-1, Mir7-2, Mir7b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (6 annotations)
Process actin cytoskeleton organization, cellular component organization, ...
Component extracellular exosome
Function actin binding, Rho GTPase binding
External Resources: FuncBase
Expression
Literature Summary: (10 records)
Data Summary: Results (310)    Tissues (146)    Images (50)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 310
cDNA source data(12)
Other mouse links: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(13) cDNA(12) Primer pair(1)
Microarray probesets(4)
Other database
links
Ensembl Gene Model ENSMUSG00000040260 (Evidence)
Entrez Gene 76441 (Evidence)
DFCI TC1729808, TC1630794, TC1591526, TC1583545
DoTS DT.101250239, DT.110555493, DT.55200535, DT.110555498, DT.87039969
NIA Mouse Gene Index U037902
Consensus CDS Project CCDS37648.1
International Mouse Phenotyping Consortium Status Daam2
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000040260 Ensembl Gene Model | MGI Sequence Detail 108316 C57BL/6J ±  kb
transcript ENSMUST00000057610 Ensembl | MGI Sequence Detail 6045 Not Applicable 
polypeptide ENSMUSP00000052085 Ensembl | MGI Sequence Detail 1115 Not Applicable 

For the selected sequences
All sequences(51) RefSeq(25) UniProt(1)
Polymorphisms
SNPs within 2kb(992 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR015425 Actin-binding FH2
InterPro IPR016024 Armadillo-type fold
InterPro IPR014767 Diaphanous autoregulatory
InterPro IPR010472 Diaphanous FH3
InterPro IPR010473 Diaphanous GTPase-binding
InterPro IPR014768 GTPase-binding/formin homology 3
Protein Ontology PR:000006257 disheveled-associated activator of morphogenesis 2
References
(Earliest) J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
(Latest) J:221126 Lee HK, et al., Daam2-PIP5K is a regulatory pathway for Wnt signaling and therapeutic target for remyelination in the CNS. Neuron. 2015 Mar 18;85(6):1227-43
All references(40)
Other
accession IDs
MGI:2146931, MGI:2147093

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
06/23/2015
MGI 5.22
The Jackson Laboratory