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Tufm
Gene Detail
 Symbol
Name
ID
Tufm
Tu translation elongation factor, mitochondrial
MGI:1923686
Synonyms 2300002G02Rik, C76308, EF-TuMT
Feature Type protein coding gene
Genetic Map
Chromosome 7
69.08 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr7:126487355-126490730 bp, + strand
From Ensembl annotation of GRCm38

  3376 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:2490  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 zebrafish

Protein SuperFamily: translation elongation factor Tu
Gene Tree: Tufm

Human
homologs
Human Homolog TUFM, Tu translation elongation factor, mitochondrial
NCBI Gene ID 7284
neXtProt AC  NX_P49411
Human Synonyms  COXPD4, EFTU, EF-TuMT, P43
Human Chr (Location)  16p11.2; chr16:28842411-28846408 (-)  GRCh38
Disease Associations  (1) Diseases Associated with Human TUFM
Mutations,
alleles, and
phenotypes
All mutations/alleles(9) : Gene trapped(5) Targeted(4)
Incidental mutations (data from Mutagenetix , APF )
Interactions
Tufm interacts with 59 markers (Mir1a-1, Mir1a-2, Mir15a, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (15 annotations)
Process translation, translational elongation
Component extracellular vesicular exosome, intracellular, ...
Function GTPase activity, GTP binding, ...
External Resources: FuncBase
Expression
Literature Summary: (1 records)
Data Summary: Results (1)    Tissues (1)    Images (1)
Theiler Stages: 23
Assay TypeResults
RNA in situ 1
cDNA source data(79)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(79) cDNA(79)
Microarray probesets(6)
Other database
links
Ensembl Gene ModelENSMUSG00000073838 (Evidence)
Entrez Gene233870 (Evidence)
UniGene197829
DFCITC1574932, TC1590742, TC1629297
DoTSDT.101305375, DT.101386438, DT.101386446, DT.536064
Consensus CDS ProjectCCDS21830.1, CCDS52398.1
International Mouse Knockout Project StatusTufm
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000073838 Ensembl Gene Model | MGI Sequence Detail 3376 C57BL/6J ±  kb
transcript ENSMUST00000098048 Ensembl | MGI Sequence Detail 1688 Not Applicable 
polypeptide ENSMUSP00000095656 Ensembl | MGI Sequence Detail 452 Not Applicable 

For the selected sequences
All sequences(35) RefSeq(6) UniProt(1)
Polymorphisms SNPs within 2kb(51 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR000795 Elongation factor, GTP-binding domain
InterPro IPR027417 P-loop containing nucleoside triphosphate hydrolase
InterPro IPR009001 Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal
InterPro IPR004541 Translation elongation factor EFTu/EF1A, bacterial/organelle
InterPro IPR004160 Translation elongation factor EFTu/EF1A, C-terminal
InterPro IPR004161 Translation elongation factor EFTu/EF1A, domain 2
InterPro IPR009000 Translation elongation/initiation factor/Ribosomal, beta-barrel
Protein Ontology PR:000016832 elongation factor Tu, mitochondrial
References (Earliest) J:60984 Ko MS, et al., Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Development. 2000 Apr;127(8):1737-49
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(36)
Other
accession IDs
MGI:2142303, MGI:2142305

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
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last database update
07/23/2014
MGI 5.19
The Jackson Laboratory