Tufm
Gene Detail

Symbol Name ID

Tufm Tu translation elongation factor, mitochondrial MGI:1923686

Synonyms

2300002G02Rik, C76308, EF-TuMT

Feature Type

protein coding gene

Genetic Map

Chromosome 7

69.08 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)

Sequence Map

Chr7:126487355-126490730 bp, + strand From Ensembl annotation of GRCm38   3376 bp   ±  kb flank VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser

Vertebrate homology

HomoloGene:2490  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 zebrafish

Protein SuperFamily: translation elongation factor Tu
Gene Tree: Tufm

Human homologs

Human Homolog		TUFM, Tu translation elongation factor, mitochondrial
NCBI Gene ID		7284
neXtProt AC		NX_P49411
Human Synonyms		COXPD4, EFTU, EF-TuMT, P43
Human Chr (Location)		16p11.2; chr16:28853732-28857729 (-)  GRCh37.p10
Disease Associations		(1) Diseases Associated with Human TUFM

Alleles and phenotypes

All alleles(9) : Targeted(4) Gene trapped(5)

Gene Ontology (GO) classifications

All GO classifications: (12 annotations)

Process	translation, translational elongation
Component	intracellular, mitochondrial inner membrane, ...
Function	GTPase activity, GTP binding, ...

External Resources: FuncBase

Expression

Literature Summary: (1 records)
Data Summary: Results (1)    Tissues (1)    Images (1)
Theiler Stages: 23

Assay Type	Results
RNA in situ	1

cDNA source data(79)
External Resources: Allen Institute   GEO   ArrayExpress

Molecular reagents

All nucleic(79) cDNA(79)
Microarray probesets(6)

Other database links

Ensembl Gene Model	ENSMUSG00000073838 (Evidence)
Entrez Gene	233870 (Evidence)
UniGene	197829
DFCI	TC1574932, TC1590742, TC1629297
DoTS	DT.101305375, DT.101386438, DT.101386446, DT.536064
Consensus CDS Project	CCDS21830.1, CCDS52398.1
International Mouse Knockout Project Status	Tufm

Sequences

Length	Strain/Species
genomic	ENSMUSG00000073838	Ensembl Gene Model | MGI Sequence Detail	3376	C57BL/6J
transcript	ENSMUST00000098048	Ensembl | MGI Sequence Detail	1688	Not Applicable
polypeptide	ENSMUSP00000095656	Ensembl | MGI Sequence Detail	452	Not Applicable

All sequences(33) RefSeq(4) UniProt(1)

Polymorphisms

SNPs(44 from dbSNP Build 128)

Protein-related information

Resource	ID	Description
InterPro	IPR000795	Elongation factor, GTP-binding domain
InterPro	IPR009001	Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal
InterPro	IPR004541	Translation elongation factor EFTu/EF1A, bacterial/organelle
InterPro	IPR004160	Translation elongation factor EFTu/EF1A, C-terminal
InterPro	IPR004161	Translation elongation factor EFTu/EF1A, domain 2
InterPro	IPR009000	Translation elongation/initiation factor/Ribosomal, beta-barrel
Protein Ontology	PR:000016832	elongation factor Tu, mitochondrial

References

(Earliest) J:60984 Ko MS, et al., Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Development. 2000 Apr;127(8):1737-49
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(36)

Other accession IDs

MGI:2142303, MGI:2142305