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Il31 Gene Detail
Summary
  • Symbol
    Il31
  • Name
    interleukin 31
  • Synonyms
    1700013B14Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1923649
    NCBI Gene: 76399
  • Gene Overview
    MyGene.info: IL31
  • Alliance
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr5:123480149-123482634 bp, - strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 5, 63.00 cM, cytoband F
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    33 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1923649
protein coding gene Chr5:123480149-123489489 (-)
129S1/SvImJ MGP_129S1SvImJ_G0030071
protein coding gene Chr5:127219436-127228613 (-)
A/J MGP_AJ_G0030036
protein coding gene Chr5:121943514-121952675 (-)
AKR/J MGP_AKRJ_G0029972
protein coding gene Chr5:125881528-125890850 (-)
BALB/cJ MGP_BALBcJ_G0030047
protein coding gene Chr5:123275200-123285284 (-)
C3H/HeJ MGP_C3HHeJ_G0029764
protein coding gene Chr5:126491912-126501236 (-)
C57BL/6NJ MGP_C57BL6NJ_G0030500
protein coding gene Chr5:132145087-132154384 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0027726
protein coding gene Chr5:116485789-116498886 (-)
CAST/EiJ MGP_CASTEiJ_G0029173
protein coding gene Chr5:125584042-125595710 (-)
CBA/J MGP_CBAJ_G0029734
protein coding gene Chr5:137339345-137348651 (-)
DBA/2J MGP_DBA2J_G0029884
protein coding gene Chr5:121960965-121970514 (-)
FVB/NJ MGP_FVBNJ_G0029840
protein coding gene Chr5:120989737-120999363 (-)
LP/J MGP_LPJ_G0029973
protein coding gene Chr5:127755883-127765122 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0029871
protein coding gene Chr5:140972004-140981331 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0030541
protein coding gene Chr5:125467266-125476888 (-)
PWK/PhJ MGP_PWKPhJ_G0028887
protein coding gene Chr5:120763085-120774930 (-)
SPRET/EiJ MGP_SPRETEiJ_G0028724
protein coding gene Chr5:123136308-123147921 (-)
WSB/EiJ MGP_WSBEiJ_G0029248
protein coding gene Chr5:126127321-126140636 (-)



Homology
more
  • Human Ortholog
    IL31, interleukin 31
  • Vertebrate Orthologs
    2
  • Human Ortholog
    IL31, interleukin 31
    Orthology source: HGNC
  • Synonyms
    IL-31
  • Links
    NCBI Gene ID: 386653
    neXtProt AC: NX_Q6EBC2
    UniProt: Q6EBC2

  • Chr Location
    12q24.31; chr12:122172030-122174199 (-)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    9 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
  • Comparison Matrix
  • Interactions
    less
    Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 76399 NCBI Gene Model | MGI Sequence Detail 2486 C57BL/6J ±  kb
    transcript NM_029594 RefSeq | MGI Sequence Detail 810 C57BL/6  
    polypeptide Q6EAL8 UniProt | EBI | MGI Sequence Detail 163 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 8
      cDNA 7
      Primer pair 1

      Microarray probesets 3
    References
    more
    • Summaries
      All 34
      Developmental Gene Expression 1
      Gene Ontology 3
      Phenotypes 9
    • Earliest
      J:134667 Roderick TH, et al., Two radiation-induced chromosomal inversions in mice (Mus musculus). Proc Natl Acad Sci U S A. 1970 Oct;67(2):961-7
    • Latest
      J:244770 Yamamura K, et al., The transcription factor EPAS1 links DOCK8 deficiency to atopic skin inflammation via IL-31 induction. Nat Commun. 2017 Jan 09;8:13946

    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    last database update
    06/18/2019
    MGI 6.14
    The Jackson Laboratory