About   Help   FAQ
Det1 Gene Detail
Summary
  • Symbol
    Det1
  • Name
    de-etiolated homolog 1 (Arabidopsis)
  • Synonyms
    2610034H20Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1923625
    NCBI Gene: 76375
  • Alliance
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr7:78822956-78847374 bp, - strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 7, 44.81 cM, cytoband D2
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    105 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1923625
protein coding gene Chr7:78821547-78847374 (-)
129S1/SvImJ MGP_129S1SvImJ_G0032380
protein coding gene Chr7:80653372-80679852 (-)
A/J MGP_AJ_G0032359
protein coding gene Chr7:78820441-78845403 (-)
AKR/J MGP_AKRJ_G0032295
protein coding gene Chr7:80513219-80535955 (-)
BALB/cJ MGP_BALBcJ_G0032371
protein coding gene Chr7:78517568-78542899 (-)
C3H/HeJ MGP_C3HHeJ_G0032084
protein coding gene Chr7:81170011-81194500 (-)
C57BL/6NJ MGP_C57BL6NJ_G0032863
protein coding gene Chr7:83829409-83853309 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0029871
protein coding gene Chr7:81378530-81401352 (-)
CAST/EiJ MGP_CASTEiJ_G0031412
protein coding gene Chr7:72011155-72035712 (-)
CBA/J MGP_CBAJ_G0032050
protein coding gene Chr7:86610504-86648233 (-)
DBA/2J MGP_DBA2J_G0032205
protein coding gene Chr7:77411131-77434260 (-)
FVB/NJ MGP_FVBNJ_G0032160
protein coding gene Chr7:77307709-77330679 (-)
LP/J MGP_LPJ_G0032286
protein coding gene Chr7:81902981-81925770 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0032197
protein coding gene Chr7:86870428-86896676 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0032881
protein coding gene Chr7:79950264-79974886 (-)
PWK/PhJ MGP_PWKPhJ_G0031132
protein coding gene Chr7:70554580-70580596 (-)
SPRET/EiJ MGP_SPRETEiJ_G0030973
protein coding gene Chr7:66923855-66953129 (-)
WSB/EiJ MGP_WSBEiJ_G0031530
protein coding gene Chr7:80267801-80294802 (-)



Homology
more
  • Human Ortholog
    DET1, DET1 partner of COP1 E3 ubiquitin ligase
  • Vertebrate Orthologs
    10
  • Human Ortholog
    DET1, DET1 partner of COP1 E3 ubiquitin ligase
    Orthology source: HomoloGene, HGNC
  • Links
    NCBI Gene ID: 55070
    neXtProt AC: NX_Q7L5Y6
    UniProt: Q7L5Y6

  • Chr Location
    15q26.1; chr15:88501924-88546703 (-)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    16 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 76375 NCBI Gene Model | MGI Sequence Detail 24419 C57BL/6J ±  kb
transcript NM_029585 RefSeq | MGI Sequence Detail 2217 C57BL/6  
polypeptide Q9D0A0 UniProt | EBI | MGI Sequence Detail 550 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 6
    cDNA 6

    Microarray probesets 3
References
more
  • Summaries
    All 34
    Gene Ontology 2
    Phenotypes 16
  • Earliest
    J:88307 Giometti CS, et al., The analysis of recessive lethal mutations in mice by using two-dimensional gel electrophoresis of liver proteins. Mutat Res. 1990 Sep;242(1):47-55
  • Latest
    J:267072 Newton K, et al., Ubiquitin ligase COP1 coordinates transcriptional programs that control cell type specification in the developing mouse brain. Proc Natl Acad Sci U S A. 2018 Oct 30;115(44):11244-11249

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
03/13/2019
MGI 6.13
The Jackson Laboratory