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Rars2
Gene Detail
 Symbol
Name
ID
Rars2
arginyl-tRNA synthetase 2, mitochondrial
MGI:1923596
Synonyms 1500002I10Rik, PRO1992, Rarsl
Feature Type protein coding gene
Genetic Map
Chromosome 4
16.84 cM
Detailed Genetic Map ± 1 cM


Mapping data(1)
Sequence Map
Chr4:34614957-34660167 bp, + strand
From VEGA annotation of GRCm38

  45211 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:5707  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

Gene Tree: Rars2

Human
homologs
Human Homolog RARS2, arginyl-tRNA synthetase 2, mitochondrial
NCBI Gene ID 57038
neXtProt AC  NX_Q5T160
Human Synonyms  ArgRS, DALRD2, dJ382I10.6, PCH6, PRO1992, RARSL
Human Chr (Location)  6q16.1; chr6:87514378-87590017 (-)  GRCh38
Disease Associations  (1) Diseases Associated with Human RARS2
Mutations,
alleles, and
phenotypes
All mutations/alleles(28) : Gene trapped(27) Targeted(1)
Incidental mutations (data from Mutagenetix , APF )
Interactions
Rars2 interacts with 71 markers (Mir10a, Mir15a, Mir26a-1, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (15 annotations)
Process arginyl-tRNA aminoacylation, translation, ...
Component cytoplasm, mitochondrion
Function aminoacyl-tRNA ligase activity, arginine-tRNA ligase activity, ...
External Resources: FuncBase
Expression
Literature Summary: (2 records)
Data Summary: Results (138)    Tissues (99)    Images (26)
Theiler Stages: 22, 23
Assay TypeResults
RNA in situ 138
cDNA source data(64)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(65) cDNA(65)
Microarray probesets(3)
Other database
links
VEGA Gene ModelOTTMUSG00000006415 (Evidence)
Ensembl Gene ModelENSMUSG00000028292 (Evidence)
Entrez Gene109093 (Evidence)
UniGene22363
DFCITC1577899
DoTSDT.101191223, DT.531077, DT.55168958
NIA Mouse Gene IndexU042520
EC6.1.1.19
Consensus CDS ProjectCCDS18029.1
International Mouse Knockout Project StatusRars2
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000006415 VEGA Gene Model | MGI Sequence Detail 45211 C57BL/6J ±  kb
transcript OTTMUST00000014627 VEGA | MGI Sequence Detail 1868 Not Applicable 
polypeptide OTTMUSP00000006801 VEGA | MGI Sequence Detail 578 Not Applicable 

For the selected sequences
All sequences(43) RefSeq(5) UniProt(2)
Polymorphisms SNPs within 2kb(241 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR009080 Aminoacyl-tRNA synthetase, class 1a, anticodon-binding
InterPro IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site
InterPro IPR001278 Arginine-tRNA ligase, class Ia
InterPro IPR005148 Arginyl tRNA synthetase N-terminal domain
InterPro IPR008909 DALR anticodon binding
InterPro IPR014729 Rossmann-like alpha/beta/alpha sandwich fold
Protein Ontology PR:000031350 probable arginine--tRNA ligase, mitochondrial
References (Earliest) J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(37)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
09/09/2014
MGI 5.19
The Jackson Laboratory