Rars2
Gene Detail

Symbol Name ID

Rars2 arginyl-tRNA synthetase 2, mitochondrial MGI:1923596

Synonyms

1500002I10Rik, PRO1992, Rarsl

Feature Type

protein coding gene

Genetic Map

Chromosome 4

16.84 cM
Detailed Genetic Map ± 1 cM


Mapping data(1)

Sequence Map

Chr4:34614957-34660167 bp, + strand From VEGA annotation of GRCm38   45211 bp   ±  kb flank VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser

Vertebrate homology

HomoloGene:5707  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 zebrafish

Gene Tree: Rars2

Human homologs

Human Homolog		RARS2, arginyl-tRNA synthetase 2, mitochondrial
NCBI Gene ID		57038
neXtProt AC		NX_Q5T160
Human Synonyms		ArgRS, DALRD2, dJ382I10.6, PCH6, PRO1992, RARSL
Human Chr (Location)		6q16.1; chr6:88224096-88299735 (-)  GRCh37.p10
Disease Associations		(1) Diseases Associated with Human RARS2

Alleles and phenotypes

All alleles(28) : Targeted(1) Gene trapped(27)

Gene Ontology (GO) classifications

All GO classifications: (14 annotations)

Process	arginyl-tRNA aminoacylation, translation, ...
Component	cytoplasm, mitochondrion
Function	aminoacyl-tRNA ligase activity, arginine-tRNA ligase activity, ...

External Resources: FuncBase

Expression

Literature Summary: (2 records)
Data Summary: Results (138)    Tissues (99)    Images (26)
Theiler Stages: 22, 23

Assay Type	Results
RNA in situ	138

cDNA source data(65)
External Resources: Allen Institute   GEO   ArrayExpress

Molecular reagents

All nucleic(66) cDNA(66)
Microarray probesets(3)

Other database links

VEGA Gene Model	OTTMUSG00000006415 (Evidence)
Ensembl Gene Model	ENSMUSG00000028292 (Evidence)
Entrez Gene	109093 (Evidence)
UniGene	22363
DFCI	TC1577899
DoTS	DT.101191223, DT.531077, DT.55168958
NIA Mouse Gene Index	U042520
EC	6.1.1.19
Consensus CDS Project	CCDS18029.1
International Mouse Knockout Project Status	Rars2

Sequences

Length	Strain/Species
genomic	OTTMUSG00000006415	VEGA Gene Model | MGI Sequence Detail	45211	C57BL/6J
transcript	OTTMUST00000014627	VEGA | MGI Sequence Detail	1868	Not Applicable
polypeptide	OTTMUSP00000006801	VEGA | MGI Sequence Detail	578	Not Applicable

All sequences(40) RefSeq(2) UniProt(2)

Polymorphisms

SNPs(209 from dbSNP Build 128)

Protein-related information

Resource	ID	Description
InterPro	IPR009080	Aminoacyl-tRNA synthetase, class 1a, anticodon-binding
InterPro	IPR001412	Aminoacyl-tRNA synthetase, class I, conserved site
InterPro	IPR001278	Arginine-tRNA ligase, class Ia
InterPro	IPR015945	Arginyl-tRNA synthetase, class Ia, core
InterPro	IPR005148	Arginyl tRNA synthetase N-terminal domain
InterPro	IPR008909	DALR anticodon binding
InterPro	IPR014729	Rossmann-like alpha/beta/alpha sandwich fold
Protein Ontology	PR:000031350	probable arginine--tRNA ligase, mitochondrial

References

(Earliest) J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(36)