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Ints5 Gene Detail
Summary
  • Symbol
    Ints5
  • Name
    integrator complex subunit 5
  • Synonyms
    1110055N21Rik, mKIAA1698
  • Feature Type
    protein coding gene
  • IDs
    MGI:1923578
    NCBI Gene: 109077
  • Alliance
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr19:8892987-8897890 bp, + strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 19, 5.95 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    22 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1923578
protein coding gene Chr19:8888926-8897890 (.)
129S1/SvImJ MGP_129S1SvImJ_G0024820
protein coding gene Chr19:6175698-6183057 (+)
A/J MGP_AJ_G0024788
protein coding gene Chr19:5840798-5850146 (+)
AKR/J MGP_AKRJ_G0024763
protein coding gene Chr19:5936751-5945626 (+)
BALB/cJ MGP_BALBcJ_G0024788
protein coding gene Chr19:5947804-5958440 (+)
C3H/HeJ MGP_C3HHeJ_G0024554
protein coding gene Chr19:6024585-6032715 (+)
C57BL/6NJ MGP_C57BL6NJ_G0025235
protein coding gene Chr19:6309604-6315905 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0022664
protein coding gene Chr19:6097028-6104446 (+)
CAST/EiJ MGP_CASTEiJ_G0024027
protein coding gene Chr19:5674907-5685170 (+)
CBA/J MGP_CBAJ_G0024528
protein coding gene Chr19:6419163-6436612 (+)
DBA/2J MGP_DBA2J_G0024655
protein coding gene Chr19:5673434-5682576 (+)
FVB/NJ MGP_FVBNJ_G0024622
protein coding gene Chr19:5746235-5752870 (+)
LP/J MGP_LPJ_G0024741
protein coding gene Chr19:6068219-6078082 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0024649
protein coding gene Chr19:6283316-6294750 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0025284
protein coding gene Chr19:5981783-5991894 (+)
PWK/PhJ MGP_PWKPhJ_G0023772
protein coding gene Chr19:5352290-5357326 (+)
SPRET/EiJ MGP_SPRETEiJ_G0023577
protein coding gene Chr19:5594126-5604042 (+)
WSB/EiJ MGP_WSBEiJ_G0024089
protein coding gene Chr19:5954012-5963088 (+)



Homology
more
  • Human Ortholog
    INTS5, integrator complex subunit 5
  • Vertebrate Orthologs
    11
  • Human Ortholog
    INTS5, integrator complex subunit 5
    Orthology source: HomoloGene, HGNC
  • Synonyms
    INT5, KIAA1698
  • Links
    NCBI Gene ID: 80789
    neXtProt AC: NX_Q6P9B9
    UniProt: Q6P9B9

  • Chr Location
    11q12.3; chr11:62646848-62653302 (-)  GRCh38.p7

  • HomoloGene
    Vertebrate Homology Class 35303
    1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 dog;1 chicken;2 zebrafish;1 frog, western clawed;1 macaque, rhesus
  • HCOP
    human homology predictions: INTS5
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype reference
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 109077 NCBI Gene Model | MGI Sequence Detail 4904 C57BL/6J ±  kb
transcript NM_176843 RefSeq | MGI Sequence Detail 3294 C57BL/6  
polypeptide Q8CHT3 UniProt | EBI | MGI Sequence Detail 1018 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 86
    cDNA 86

    Microarray probesets 7
References
more
  • Summaries
    All 23
    Developmental Gene Expression 1
    Gene Ontology 2
    Phenotypes 1
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:157819 Shimogori T, et al., A genomic atlas of mouse hypothalamic development. Nat Neurosci. 2010;13(6):767-75

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/06/2018
MGI 6.13
The Jackson Laboratory