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Exosc4 Gene Detail
Summary
  • Symbol
    Exosc4
  • Name
    exosome component 4
  • Synonyms
    1110039I09Rik, 1500001N04Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1923576
    NCBI Gene: 109075
  • Gene Overview
    MyGene.info: EXOSC4
  • Alliance
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr15:76327397-76330670 bp, + strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 15, 35.72 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    26 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1923576
protein coding gene Chr15:76327397-76330677 (.)
129S1/SvImJ MGP_129S1SvImJ_G0021983
protein coding gene Chr15:76396621-76399895 (+)
A/J MGP_AJ_G0021941
protein coding gene Chr15:73615435-73618718 (+)
AKR/J MGP_AKRJ_G0021924
protein coding gene Chr15:75612944-75616216 (+)
BALB/cJ MGP_BALBcJ_G0021950
protein coding gene Chr15:73641545-73644820 (+)
C3H/HeJ MGP_C3HHeJ_G0021722
protein coding gene Chr15:75657595-75660868 (+)
C57BL/6NJ MGP_C57BL6NJ_G0022390
protein coding gene Chr15:79250889-79254197 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0019919
protein coding gene Chr15:70276704-70280211 (+)
CAST/EiJ MGP_CASTEiJ_G0021241
protein coding gene Chr15:76455600-76458878 (+)
CBA/J MGP_CBAJ_G0021689
protein coding gene Chr15:81749712-81752983 (+)
DBA/2J MGP_DBA2J_G0021814
protein coding gene Chr15:73151534-73154804 (+)
FVB/NJ MGP_FVBNJ_G0021795
protein coding gene Chr15:72199680-72203957 (+)
LP/J MGP_LPJ_G0021885
protein coding gene Chr15:76487047-76492450 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0021819
protein coding gene Chr15:87087925-87091191 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0022410
protein coding gene Chr15:75857130-75860405 (+)
PWK/PhJ MGP_PWKPhJ_G0020982
protein coding gene Chr15:73301175-73304571 (+)
SPRET/EiJ MGP_SPRETEiJ_G0020822
protein coding gene Chr15:75578423-75581680 (+)
WSB/EiJ MGP_WSBEiJ_G0021293
protein coding gene Chr15:75954404-75957693 (+)



Homology
more
  • Human Ortholog
    EXOSC4, exosome component 4
  • Vertebrate Orthologs
    9
  • Human Ortholog
    EXOSC4, exosome component 4
    Orthology source: HomoloGene, HGNC
  • Synonyms
    hRrp41p, p12A, RRP41, RRP41A, Rrp41p, SKI6, Ski6p
  • Links
    NCBI Gene ID: 54512
    neXtProt AC: NX_Q9NPD3
    UniProt: Q9NPD3

  • Chr Location
    8q24.3; chr8:144064092-144080648 (+)  GRCh38.p7

Human Diseases
less
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    26 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 109075 NCBI Gene Model | MGI Sequence Detail 3274 C57BL/6J ±  kb
transcript NM_175399 RefSeq | MGI Sequence Detail 1789 C57BL/6  
polypeptide Q921I9 UniProt | EBI | MGI Sequence Detail 245 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 82
    cDNA 82

    Microarray probesets 3
Other
Accession IDs
less
MGI:1916201
References
more
  • Summaries
    All 49
    Diseases 1
    Gene Ontology 6
    Phenotypes 26
  • Earliest
    J:109968 Roderick TH, et al., Nineteen paracentric chromosomal inversions in mice. Genetics. 1974 Jan;76(1):109-17
  • Latest
    J:233611 Hirata A, et al., Homeobox family Hoxc localization during murine palate formation. Congenit Anom (Kyoto). 2016 Jul;56(4):172-9

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/06/2018
MGI 6.13
The Jackson Laboratory