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Rab1b
Gene Detail
Symbol

Name
ID
Rab1b
RAB1B, member RAS oncogene family
MGI:1923558
Synonyms
1110011F09Rik
Feature Type
protein coding gene
Genetic Map
Chromosome 19
4.25 cM, cytoband A
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr19:5099207-5106996 bp, - strand
From NCBI annotation of GRCm38

  7790 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:128838  Vertebrate Homology Class
1 human; 1 mouse; 2 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 zebrafish

HCOP human homology predictions: RAB1B
Protein SuperFamily: Ras-related protein Rab
Gene Tree: Rab1b

Human
homologs
RAB1B, RAB1B, member RAS oncogene family
Orthology source: HGNC, HomoloGene

IDs:
NCBI Gene ID: 81876
neXtProt AC: NX_Q9H0U4

Human Chr (Location): 11q12; chr11:66268585-66277492 (+)  GRCh38.p2

Mutations,
alleles, and
phenotypes
All mutations/alleles(13) : Gene trapped(10) Targeted(3)
Incidental mutations (data from Mutagenetix , APF )
 
Mice homozygous for a gene trap insertion do not exhibit a detectable mutant phenotype.
 
Interactions
Rab1b interacts with 189 markers (Mir7-1, Mir7-2, Mir7b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (23 annotations)
Process autophagy, ER to Golgi vesicle-mediated transport, ...
Component cytoplasm, endoplasmic reticulum-Golgi intermediate compartment, ...
Function GTPase activity, GTP binding, ...
External Resources: FuncBase
Expression
cDNA source data(184)
Other mouse links: Allen Institute   GEO   Expression Atlas
Other vertebrate links: ZFIN rab1bb    NEW 
Molecular
reagents
All nucleic(184) cDNA(184)
Microarray probesets(2)
Other database
links
Ensembl Gene Model ENSMUSG00000024870 (Evidence)
Entrez Gene 76308 (Evidence)
UniGene 182563
DFCI TC1572108
DoTS DT.496462
NIA Mouse Gene Index U019065
Consensus CDS Project CCDS29452.1
International Mouse Phenotyping Consortium Status Rab1b
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic 76308 NCBI Gene Model | MGI Sequence Detail 7790 C57BL/6J ±  kb
transcript NM_029576 RefSeq | MGI Sequence Detail 1835 C57BL/6 
polypeptide Q9D1G1 UniProt | EBI | MGI Sequence Detail 201 Not Applicable 

For the selected sequences
All sequences(29) RefSeq(2) UniProt(3)
Polymorphisms
SNPs within 2kb(27 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR027417 P-loop containing nucleoside triphosphate hydrolase
InterPro IPR001806 Small GTPase superfamily
InterPro IPR003579 Small GTPase superfamily, Rab type
InterPro IPR005225 Small GTP-binding protein domain
Protein Ontology PR:000013592 ras-related protein Rab-1B
Graphical View of Protein Domain Structure
References
(Earliest) J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
(Latest) J:169417 Valkova C, et al., Sorting receptor Rer1 controls surface expression of muscle acetylcholine receptors by ER retention of unassembled alpha-subunits. Proc Natl Acad Sci U S A. 2011 Jan 11;108(2):621-5
All references(33)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
07/21/2015
MGI 5.22
The Jackson Laboratory