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Gstk1
Gene Detail
Symbol

Name
ID
Gstk1
glutathione S-transferase kappa 1
MGI:1923513
Synonyms
0610025I19Rik, DsbA-L
Feature Type
protein coding gene
Genetic Map
Chromosome 6
20.52 cM
Detailed Genetic Map ± 1 cM


Mapping data(3)
Sequence Map
Chr6:42245935-42250441 bp, + strand
From NCBI annotation of GRCm38

  4507 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:41075  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 2 western clawed frog; 5 zebrafish

HCOP human homology predictions: GSTK1
Protein SuperFamily: HCCA isomerase/glutathione S-transferase kappa
Gene Tree: Gstk1

Human
homologs
GSTK1, glutathione S-transferase kappa 1
Orthology source: HomoloGene, HGNC

IDs:
NCBI Gene ID: 373156
neXtProt AC: NX_Q9Y2Q3

Human Synonyms: GST, GST13, GST 13-13, GST13-13, GSTK1-1, hGSTK1

Human Chr (Location): 7q34; chr7:143263429-143269129 (+)  GRCh38.p2

Mutations,
alleles, and
phenotypes
All mutations/alleles(3) : Targeted(3)
Incidental mutations (data from Mutagenetix , APF )
 
Mice homozygous for a knock-out allele exhibit abnormal male survival curves associated with increased glomerular nephropathy.
 
Interactions
Gstk1 interacts with 35 markers (Mir124a-1, Mir124a-2, Mir124a-3, ...)
Gene Ontology
(GO)
classifications
Expression
Literature Summary: (1 records)
Data Summary: Results (94)    Tissues (94)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 94
cDNA source data(52)
Other mouse links: Allen Institute   GEO   Expression Atlas
Other vertebrate links: Xenbase gstk1 ; ZFIN gstk1    NEW 
Molecular
reagents
All nucleic(53) cDNA(52) Primer pair(1)
Microarray probesets(3)
Other database
links
Ensembl Gene Model ENSMUSG00000029864 (Evidence)
Entrez Gene 76263 (Evidence)
UniGene 267014
DFCI TC1745076, TC1580117
DoTS DT.535144, DT.94395988
NIA Mouse Gene Index U006747
EC 2.5.1.18
Consensus CDS Project CCDS20063.1
International Mouse Phenotyping Consortium Status Gstk1
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic 76263 NCBI Gene Model | MGI Sequence Detail 4507 C57BL/6J ±  kb
transcript NM_029555 RefSeq | MGI Sequence Detail 930 C57BL/6 
polypeptide Q9DCM2 UniProt | EBI | MGI Sequence Detail 226 Not Applicable 

For the selected sequences
All sequences(20) RefSeq(2) UniProt(1)
Polymorphisms
SNPs within 2kb(61 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR001853 DSBA-like thioredoxin domain
InterPro IPR014440 HCCA isomerase/glutathione S-transferase kappa
InterPro IPR012336 Thioredoxin-like fold
Protein Ontology PR:000008299 glutathione S-transferase kappa 1
Graphical View of Protein Domain Structure
References
(Earliest) J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
(Latest) J:177201 Blackburn AC, et al., Glutathione transferase kappa deficiency causes glomerular nephropathy without overt oxidative stress. Lab Invest. 2011 Nov;91(11):1572-83
All references(38)
Other
accession IDs
MGI:2139339

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
06/23/2015
MGI 5.22
The Jackson Laboratory