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Ercc6l2 Gene Detail
Summary
  • Symbol
    Ercc6l2
  • Name
    excision repair cross-complementing rodent repair deficiency, complementation group 6 like 2
  • Synonyms
    0610007P08Rik, 1700019D06Rik, 9330134C04Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1923501
    NCBI Gene: 76251
  • Alliance
    gene page
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr13:63815240-63900302 bp, + strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 13, 33.10 cM, cytoband B3
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    566 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1923501
 protein coding gene Chr13:63815058-63900302 (+)
129S1/SvImJ MGP_129S1SvImJ_G0020671
 protein coding gene Chr13:63801433-63901321 (+)
A/J MGP_AJ_G0020625
 protein coding gene Chr13:61486018-61572310 (+)
AKR/J MGP_AKRJ_G0020602
 protein coding gene Chr13:63532766-63625454 (+)
BALB/cJ MGP_BALBcJ_G0020623
 protein coding gene Chr13:61918485-62001893 (+)
C3H/HeJ MGP_C3HHeJ_G0020418
 protein coding gene Chr13:63066729-63152719 (+)
C57BL/6NJ MGP_C57BL6NJ_G0021059
 protein coding gene Chr13:65869725-65958477 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0018635
 protein coding gene Chr13:59142184-59238242 (+)
CAST/EiJ MGP_CASTEiJ_G0019935
 protein coding gene Chr13:63074000-63162107 (+)
CBA/J MGP_CBAJ_G0020378
 protein coding gene Chr13:68409574-68506310 (+)
DBA/2J MGP_DBA2J_G0020503
 protein coding gene Chr13:61324599-61416314 (+)
FVB/NJ MGP_FVBNJ_G0020482
 protein coding gene Chr13:60435420-60520202 (+)
LP/J MGP_LPJ_G0020577
 protein coding gene Chr13:64086708-64176813 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0020511
 protein coding gene Chr13:67368615-67467783 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0021101
 protein coding gene Chr13:62847632-62937462 (+)
PWK/PhJ MGP_PWKPhJ_G0019689
 protein coding gene Chr13:60880611-60966916 (+)
SPRET/EiJ MGP_SPRETEiJ_G0019515
 protein coding gene Chr13:61001054-61093182 (+)
WSB/EiJ MGP_WSBEiJ_G0019995
 protein coding gene Chr13:63328855-63421388 (+)



Homology
more
  • Human Ortholog
    ERCC6L2, ERCC excision repair 6 like 2
  • Vertebrate Orthologs
    7
  • Human Ortholog
    ERCC6L2, ERCC excision repair 6 like 2
    Orthology source: HomoloGene, HGNC
  • Synonyms
    BMFS2, C9orf102, RAD26L, SR278
  • Links
    NCBI Gene ID: 375748
    neXtProt AC: NX_Q5T890
    UniProt: Q5T890

  • Chr Location
    9q22.32; chr9:95875618-96041092 (+)  GRCh38.p7
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    8 phenotype references
  • All Mutations and Alleles
    4
  • Chemically induced (other)
    1
  • Gene trapped
    1
  • Targeted
    2
  • Genomic Mutations
    1 involving Ercc6l2
  • Incidental Mutations
    APF , CvDC
  • Find Mice (IMSR)
    2 strains or lines available
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    17
  • GO References
    3
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
    81
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000021470 Ensembl Gene Model | MGI Sequence Detail 85063 C57BL/6J ±  kb
transcript ENSMUST00000238465 Ensembl | MGI Sequence Detail 4614 Not Applicable  
polypeptide ENSMUSP00000158755 Ensembl | MGI Sequence Detail 1537 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    7 Sequences
  • Protein Ontology
    PR:000031586 DNA excision repair protein ERCC-6-like 2
    (term hierarchy)
  • EC
    3.6.4.-
  • InterPro Domains
    IPR002464 DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site
    IPR029256 Helicase-associated putative binding domain
    IPR001650 Helicase, C-terminal
    IPR014001 Helicase superfamily 1/2, ATP-binding domain
    IPR027417 P-loop containing nucleoside triphosphate hydrolase
    IPR038718 SNF2-like, N-terminal domain superfamily
    IPR000330 SNF2-related, N-terminal domain
Molecular
Reagents
less
  • All nucleic 81
    cDNA 81

    Microarray probesets 8
Other
Accession IDs
less
MGI:1916653, MGI:3689365
References
more
  • Summaries
    All 31
    Gene Ontology 3
    Phenotypes 8
  • Earliest
    J:182573 Roderick TH, Producing and detecting paracentric chromosomal inversions in mice. Mutat Res. 1971 Jan;11(1):59-69
  • Latest
    J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
08/13/2019
MGI 6.14 		The Jackson Laboratory