Tmem275 Gene Detail

Summary

• Symbol
  Tmem275
• Name
  transmembrane protein 275
• Synonyms
  6430628N08Rik

• Feature Type
  protein coding gene
• IDs
  MGI:1923487
  NCBI Gene: 76237
• Alliance
  gene page

Location &
Maps

• Sequence Map
  Chr4:115747863-115756425 bp, + strand

  From NCBI annotation of GRCm39
  

• View this region in JBrowse
  

• Genome Browsers
  Ensembl | UCSC | NCBI

• Genetic Map
  Chromosome 4, 53.06 cM, cytoband C7
• Mapping Data
  2 experiments

Strain
Comparison

• SNPs within 2kb
  101 from dbSNP Build 142
• Strain Annotations
  18

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_1923487	protein coding gene	Chr4:115747862-115756425 (+)
129S1/SvImJ	MGP_129S1SvImJ_G0028612	protein coding gene	Chr4:116734956-116743517 (+)
A/J	MGP_AJ_G0028573	protein coding gene	Chr4:112280762-112289337 (+)
AKR/J	MGP_AKRJ_G0028522	protein coding gene	Chr4:114687198-114695859 (+)
BALB/cJ	MGP_BALBcJ_G0028594	protein coding gene	Chr4:112909191-112917747 (+)
C3H/HeJ	MGP_C3HHeJ_G0028308	protein coding gene	Chr4:116266428-116275046 (+)
C57BL/6NJ	MGP_C57BL6NJ_G0029035	protein coding gene	Chr4:121259423-121267977 (+)
CAROLI/EiJ	MGP_CAROLIEiJ_G0026319	protein coding gene	Chr4:106327157-106335755 (+)
CAST/EiJ	MGP_CASTEiJ_G0027742	protein coding gene	Chr4:113473976-113482543 (+)
CBA/J	MGP_CBAJ_G0028275	protein coding gene	Chr4:124552766-124561347 (+)
DBA/2J	MGP_DBA2J_G0028423	protein coding gene	Chr4:112929970-112938398 (+)
FVB/NJ	MGP_FVBNJ_G0028391	protein coding gene	Chr4:111416128-111424960 (+)
LP/J	MGP_LPJ_G0028525	protein coding gene	Chr4:116952240-116960846 (+)
NOD/ShiLtJ	MGP_NODShiLtJ_G0028418	protein coding gene	Chr4:129571973-129580400 (+)
NZO/HlLtJ	MGP_NZOHlLtJ_G0029072	protein coding gene	Chr4:115844760-115853325 (+)
PWK/PhJ	MGP_PWKPhJ_G0027468	protein coding gene	Chr4:109688767-109697362 (+)
SPRET/EiJ	MGP_SPRETEiJ_G0027291	protein coding gene	Chr4:112089190-112097734 (+)
WSB/EiJ	MGP_WSBEiJ_G0027821	protein coding gene	Chr4:115710786-115719333 (+)

Homology

• Human Ortholog
  TMEM275, transmembrane protein 275

• Vertebrate Orthologs
  2

Vertebrate Orthology Source

Alliance of Genome Resources

• Human Ortholog
  TMEM275, transmembrane protein 275
  
• Links
  HGNC:53938

  NCBI Gene ID: 105378696

  UniProt: A0A0U1RQS6

  
  
• Chr Location
  chr1:46532166-46543969 (-)  GRCh38

---

• MGI Vertebrate Homology
  Tmem275 stringent orthology
  1 human;1 mouse;1 zebrafish
  
• HCOP
  vertebrate homology predictions: TMEM275
• Gene Tree
  Tmem275
  

Mutations,
Alleles, and
Phenotypes

• Phenotype Summary
  6 phenotype references
  

• All Mutations and Alleles
  4
• Chemically induced (other)
  2
• Radiation induced
  1
• Targeted
  1
• Genomic Mutations
  4 involving Tmem275
• Find Mice (IMSR)
  2 strains or lines available

Gene Ontology
(GO)
Classifications

• All GO Annotations
  1
• GO References
  1

Expression

• Assay Results
  706
• cDNA Data
  1

Tissue x Stage Matrix

• Other Mouse Links
  GEO
  Expression Atlas

Sequences &
Gene Models

• All Sequences
  30
• RefSeq
  3
• UniProt
  3
• CCDS
  CCDS89812.1

• Ensembl
  ENSMUSG00000034185 (Evidence)
• NCBI Gene
  76237

Representative Sequences			Length	Strain/Species
genomic	76237	NCBI Gene Model | MGI Sequence Detail	8563	C57BL/6J
transcript	NM_001357060	RefSeq | MGI Sequence Detail	1621	C57BL/6
polypeptide	A0A0U1RQ45	UniProt | EBI | MGI Sequence Detail	177	Not Applicable

Protein
Information

• UniProt
  3 Sequences
• Protein Ontology
  PR:000059650 transmembrane protein 275
  (term hierarchy)

Molecular
Reagents

• All nucleic 1

  cDNA 1

  
  

  Microarray probesets 1

References

• Summaries
  All 21

  Gene Ontology 1

  Phenotypes 6
• Earliest
  J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
• Latest
  J:148802 Boles MK, et al., A mouse chromosome 4 balancer ENU-mutagenesis screen isolates eleven lethal lines. BMC Genet. 2009;10:12