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Magi3 Gene Detail
Summary
  • Symbol
    Magi3
  • Name
    membrane associated guanylate kinase, WW and PDZ domain containing 3
  • Synonyms
    4732496O19Rik, 6530407C02Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1923484
    NCBI Gene: 99470
  • Gene Overview
    MyGene.info: MAGI3
Location & Maps
more
  • Sequence Map
    Chr3:104013259-104220374 bp, - strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      207116 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 3, 45.52 cM
  • Mapping Data
    4 experiments
Homology
more
  • Human Ortholog
    MAGI3, membrane associated guanylate kinase, WW and PDZ domain containing 3
  • Vertebrate Orthologs
    10
  • Human Ortholog
    MAGI3, membrane associated guanylate kinase, WW and PDZ domain containing 3
    Orthology source: HomoloGene, HGNC
  • Synonyms
    dJ730K3.2, MAGI-3
  • Links
    NCBI Gene ID: 260425
    neXtProt AC: NX_Q5TCQ9

  • Chr Location
    1p13.2; chr1:113390474-113685923 (+)  GRCh38.p2

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    6 phenotype references
  • All Mutations and Alleles
    7
  • Chemically induced (other)
    1
  • Gene trapped
    3
  • Radiation induced
    1
  • Targeted
    2
  • Genomic Mutations
    2 involving Magi3
  • Incidental Mutations
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000028459 VEGA Gene Model | MGI Sequence Detail 207116 C57BL/6J ±  kb
transcript OTTMUST00000071048 VEGA | MGI Sequence Detail 5912 Not Applicable  
polypeptide OTTMUSP00000036317 VEGA | MGI Sequence Detail 1476 Not Applicable  
For the selected sequence
Polymorphisms
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  • SNPs within 2kb
    407 from dbSNP Build 142
Protein
Information
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  • UniProt
    3 Sequences
  • Protein Ontology
    PR:000010085 membrane-associated guanylate kinase, WW and PDZ domain-containing protein 3
  • InterPro Domains
    IPR020590 Guanylate kinase, conserved site
    IPR008144 Guanylate kinase-like domain
    IPR008145 Guanylate kinase/L-type calcium channel beta subunit
    IPR030035 Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 3
    IPR001478 PDZ domain
    IPR027417 P-loop containing nucleoside triphosphate hydrolase
    IPR001202 WW domain
Molecular
Reagents
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  • All nucleic 57
    cDNA 56
    Primer pair 1

    Microarray probesets 7
Other
Accession IDs
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MGI:2139551, MGI:2139629
References
more
  • Summaries
    All 29
    Developmental Gene Expression 3
    Gene Ontology 5
    Phenotypes 6
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
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last database update
09/13/2016
MGI 6.05
The Jackson Laboratory