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Dnttip1 Gene Detail
Summary
  • Symbol
    Dnttip1
  • Name
    deoxynucleotidyltransferase, terminal, interacting protein 1
  • Synonyms
    6430706C13Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1923483
    NCBI Gene: 76233
  • Alliance
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr2:164746015-164768220 bp, + strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 2, 85.27 cM, cytoband H3
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    85 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1923483
protein coding gene Chr2:164745983-164768607 (+)
129S1/SvImJ MGP_129S1SvImJ_G0026870
protein coding gene Chr2:170240463-170266516 (+)
A/J MGP_AJ_G0026837
protein coding gene Chr2:163282913-163306343 (+)
AKR/J MGP_AKRJ_G0026808
protein coding gene Chr2:168138687-168161306 (+)
BALB/cJ MGP_BALBcJ_G0026846
protein coding gene Chr2:163642351-163665020 (+)
C3H/HeJ MGP_C3HHeJ_G0026588
protein coding gene Chr2:168499420-168524642 (+)
C57BL/6NJ MGP_C57BL6NJ_G0027293
protein coding gene Chr2:175170482-175195941 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0024664
protein coding gene Chr2:156691991-156713549 (+)
CAST/EiJ MGP_CASTEiJ_G0026046
protein coding gene Chr2:168915837-168940116 (+)
CBA/J MGP_CBAJ_G0026565
protein coding gene Chr2:181528370-181550992 (+)
DBA/2J MGP_DBA2J_G0026703
protein coding gene Chr2:162449949-162473033 (+)
FVB/NJ MGP_FVBNJ_G0026669
protein coding gene Chr2:160870703-160893209 (+)
LP/J MGP_LPJ_G0026805
protein coding gene Chr2:170301155-170325007 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0026688
protein coding gene Chr2:185089238-185114515 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0027350
protein coding gene Chr2:168039719-168064754 (+)
PWK/PhJ MGP_PWKPhJ_G0025783
protein coding gene Chr2:162049938-162072791 (+)
SPRET/EiJ MGP_SPRETEiJ_G0025584
protein coding gene Chr2:166944182-166965246 (+)
WSB/EiJ MGP_WSBEiJ_G0026119
protein coding gene Chr2:168923997-168947470 (+)



Homology
more
  • Human Ortholog
    DNTTIP1, deoxynucleotidyltransferase terminal interacting protein 1
  • Vertebrate Orthologs
    10
  • Human Ortholog
    DNTTIP1, deoxynucleotidyltransferase terminal interacting protein 1
    Orthology source: HomoloGene, HGNC
  • Synonyms
    C20orf167, dJ447F3.4, Tdif1
  • Links
    NCBI Gene ID: 116092
    neXtProt AC: NX_Q9H147
    UniProt: Q9H147

  • Chr Location
    20q13.12; chr20:45791937-45811427 (+)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    2 phenotypes from 1 allele in 1 genetic background
    8 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 76233 NCBI Gene Model | MGI Sequence Detail 22206 C57BL/6J ±  kb
transcript NM_133763 RefSeq | MGI Sequence Detail 1257 Not Specified  
polypeptide Q99LB0 UniProt | EBI | MGI Sequence Detail 328 Not Applicable  
For the selected sequence
Protein
Information
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  • UniProt
    4 Sequences
  • Protein Ontology
    PR:000006612 deoxynucleotidyltransferase terminal-interacting protein 1
  • InterPro Domains
    IPR041384 DNTTIP1, dimerisation domain
    IPR026064 Terminal deoxynucleotidyltransferase-interacting factor 1
Molecular
Reagents
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  • All nucleic 75
    cDNA 75

    Microarray probesets 4
References
more
  • Summaries
    All 31
    Developmental Gene Expression 1
    Gene Ontology 3
    Phenotypes 8
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:263646 Horiuchi K, et al., Impaired Spermatogenesis, Muscle, and Erythrocyte Function in U12 Intron Splicing-Defective Zrsr1 Mutant Mice. Cell Rep. 2018 Apr 3;23(1):143-155

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
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last database update
05/14/2019
MGI 6.14
The Jackson Laboratory