Igsf10 MGI Mouse Gene Detail - MGI:1923481 - immunoglobulin superfamily, member 10

Igsf10 Gene Detail

Symbol

Igsf10
Name

immunoglobulin superfamily, member 10
Synonyms

6530405F15Rik, Adlican2, CMF608

Feature Type

protein coding gene
IDs

MGI:1923481
NCBI Gene: 242050
Alliance

gene page

Sequence Map

Chr3:59317925-59344394 bp, - strand
From VEGA annotation of GRCm38

Mouse Genome Browser
Download
Sequence

26470 bp ± kb flank
Genome Browsers

VEGA | Ensembl | UCSC | NCBI

Genetic Map

Chromosome 3, 29.03 cM
Mapping Data

2 experiments

Human Ortholog

IGSF10, immunoglobulin superfamily member 10

Vertebrate Orthologs

9

Human Ortholog

IGSF10, immunoglobulin superfamily member 10
Orthology source: HomoloGene, HGNC
Synonyms

CMF608
Links

HGNC:26384

NCBI Gene ID: 285313

neXtProt AC: NX_Q6WRI0

UniProt: Q6WRI0
Chr Location

3q25.1; chr3:151435051-151619926 (-) GRCh38.p7

HomoloGene

Vertebrate Homology Class 18712
1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 dog;1 chicken;1 frog, western clawed;1 macaque, rhesus
HCOP

human homology predictions: IGSF10
Gene Tree

Igsf10

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References

1 with disease annotations

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Phenotype Summary

2 phenotype references

All Mutations and Alleles

3
Radiation induced

1
Targeted

2
Genomic Mutations

1 involving Igsf10
Incidental Mutations

Mutagenetix , APF , CvDC
Find Mice (IMSR)

51 strains or lines available

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All GO Annotations

4
GO References

4

External Resources

FuncBase

Molecular Function

carbohydrate derivative binding	cytoskeletal protein binding	DNA binding	enzyme regulator	hydrolase	ligase	lipid binding	oxidoreductase	receptor binding	RNA binding	transcription	transferase	transporter

Biological Process

nucleic acid-templated transcription	carbohydrate derivative metabolism	cell death	cell differentiation	cell proliferation	cellular component organization	establishment of localization	homeostatic process	immune system process	lipid metabolic process	protein metabolic process	response to stimulus	signaling	system development

Cellular Component

cell projection	cytoplasmic vesicle	cytoskeleton	cytosol	endoplasmic reticulum	endosome	extracellular region	Golgi apparatus	mitochondrion	non-membrane-bounded organelle	nucleus	organelle envelope	organelle lumen	plasma membrane	synapse	vacuole

Click cells to view annotations.

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Expression Overview

GXD's primary emphasis is on endogenous gene expression during development. Click on grid cells to view annotations.

Blue cells = expressed in wild-type.
Gray triangles = other expression annotations only
(e.g. absence of expression or data from mutants).

early conceptus	embryo ectoderm	embryo endoderm	embryo mesoderm	embryo mesenchyme	extraembryonic component	alimentary system	auditory system	branchial arches	cardiovascular system	connective tissue	endocrine system	exocrine system	hemolymphoid system	integumental system	limbs	liver and biliary system	musculoskeletal system	nervous system	olfactory system	reproductive system	respiratory system	urinary system	visual system

Click cells to view annotations.

Assay Results

77
Tissues

32
cDNA Data

10
Literature Summary

4

Images

Tissue x Stage Matrix

Other Mouse Links

Allen Institute

GEO

Expression Atlas
Other Vertebrate Links

Xenbase igsf10

ZFIN igsf10

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Igsf10 interacts with 291 markers (Mir1a-1, Mir1a-2, Mir7-1, ...) View All

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All Sequences

43
RefSeq

15
UniProt

2
CCDS

CCDS50915.1

			Length	Strain/Species	Flank
genomic	OTTMUSG00000052181	VEGA Gene Model \| MGI Sequence Detail	26470	C57BL/6J	± kb
transcript	OTTMUST00000131111	VEGA \| MGI Sequence Detail	8484	Not Applicable
polypeptide	OTTMUSP00000070171	VEGA \| MGI Sequence Detail	2594	Not Applicable

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SNPs within 2kb

148 from dbSNP Build 142

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UniProt

2 Sequences
Protein Ontology

PR:000008969 immunoglobulin superfamily member 10

(term hierarchy)
InterPro Domains

IPR000483 Cysteine-rich flanking region, C-terminal

IPR013098 Immunoglobulin I-set

IPR007110 Immunoglobulin-like domain

IPR036179 Immunoglobulin-like domain superfamily

IPR013783 Immunoglobulin-like fold

IPR003599 Immunoglobulin subtype

IPR003598 Immunoglobulin subtype 2

IPR013106 Immunoglobulin V-set domain

IPR001611 Leucine-rich repeat

IPR032675 Leucine-rich repeat domain superfamily

IPR000372 Leucine-rich repeat N-terminal domain

IPR003591 Leucine-rich repeat, typical subtype

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All nucleic 14

cDNA 12

Primer pair 2

Microarray probesets 3

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MGI:2139569, MGI:2139590, MGI:2139693

Summaries

All 27

Developmental Gene Expression 4

Diseases 1

Gene Ontology 4

Phenotypes 2
Earliest

J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
Latest

J:240579 Howard SR, et al., IGSF10 mutations dysregulate gonadotropin-releasing hormone neuronal migration resulting in delayed puberty. EMBO Mol Med. 2016 Jun;8(6):626-42

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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