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Igsf10 Gene Detail
Summary
  • Symbol
    Igsf10
  • Name
    immunoglobulin superfamily, member 10
  • Synonyms
    6530405F15Rik, Adlican2, CMF608
  • Feature Type
    protein coding gene
  • IDs
    MGI:1923481
    NCBI Gene: 242050
  • Alliance
    gene page
  • Transcription Start Sites
    8 TSS
Location &
Maps
more
  • Sequence Map
    Chr3:59316735-59344394 bp, - strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 3, 29.03 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    149 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1923481
 protein coding gene Chr3:59316735-59344438 (-)
129S1/SvImJ MGP_129S1SvImJ_G0027247
 protein coding gene Chr3:58188537-58220066 (-)
A/J MGP_AJ_G0027207
 protein coding gene Chr3:56368873-56396195 (-)
AKR/J MGP_AKRJ_G0027177
 protein coding gene Chr3:57544314-57571945 (-)
BALB/cJ MGP_BALBcJ_G0027220
 protein coding gene Chr3:56176589-56203809 (-)
C3H/HeJ MGP_C3HHeJ_G0026963
 protein coding gene Chr3:57760118-57787470 (-)
C57BL/6NJ MGP_C57BL6NJ_G0027666
 protein coding gene Chr3:60336872-60370303 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0025020
 protein coding gene Chr3:52728618-52756652 (-)
CAST/EiJ MGP_CASTEiJ_G0026415
 protein coding gene Chr3:57940060-57968858 (-)
CBA/J MGP_CBAJ_G0026939
 protein coding gene Chr3:62331856-62361855 (-)
DBA/2J MGP_DBA2J_G0027073
 protein coding gene Chr3:55882850-55911209 (-)
FVB/NJ MGP_FVBNJ_G0027041
 protein coding gene Chr3:54829447-54858105 (-)
LP/J MGP_LPJ_G0027185
 protein coding gene Chr3:58944594-58972974 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0027059
 protein coding gene Chr3:66474952-66513828 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0027724
 protein coding gene Chr3:57518139-57546870 (-)
PWK/PhJ MGP_PWKPhJ_G0026147
 protein coding gene Chr3:55518560-55546818 (-)
SPRET/EiJ MGP_SPRETEiJ_G0025960
 protein coding gene Chr3:57220764-57246967 (-)
WSB/EiJ MGP_WSBEiJ_G0026489
 protein coding gene Chr3:57594351-57623317 (-)



Homology
more
  • Human Ortholog
    IGSF10, immunoglobulin superfamily member 10
  • Vertebrate Orthologs
    9
  • Human Ortholog
    IGSF10, immunoglobulin superfamily member 10
    Orthology source: HomoloGene, HGNC
  • Synonyms
    CMF608
  • Links
    NCBI Gene ID: 285313
    neXtProt AC: NX_Q6WRI0
    UniProt: Q6WRI0

  • Chr Location
    3q25.1; chr3:151435051-151619926 (-)  GRCh38.p7
Human Diseases
less
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    2 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    5
  • GO References
    5
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    708
  • Tissues
    32
  • cDNA Data
    11
  • Literature Summary
    4
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000036334 Ensembl Gene Model | MGI Sequence Detail 27660 C57BL/6J ±  kb
transcript ENSMUST00000193455 Ensembl | MGI Sequence Detail 8484 Not Applicable  
polypeptide ENSMUSP00000141971 Ensembl | MGI Sequence Detail 2594 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 15
    cDNA 13
    Primer pair 2

    Microarray probesets 3
Other
Accession IDs
less
MGI:2139569, MGI:2139590, MGI:2139693
References
more
  • Summaries
    All 28
    Developmental Gene Expression 4
    Diseases 1
    Gene Ontology 5
    Phenotypes 2
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:240579 Howard SR, et al., IGSF10 mutations dysregulate gonadotropin-releasing hormone neuronal migration resulting in delayed puberty. EMBO Mol Med. 2016 Jun;8(6):626-42
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
07/07/2020
MGI 6.15 		The Jackson Laboratory