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Snrnp35 Gene Detail
Summary
  • Symbol
    Snrnp35
  • Name
    small nuclear ribonucleoprotein 35 (U11/U12)
  • Synonyms
    6330548G22Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1923417
    NCBI Gene: 76167
  • Alliance
    gene page
  • Transcription Start Sites
    5 TSS
Location &
Maps
more
  • Sequence Map
    Chr5:124621197-124629187 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 5, 63.61 cM, cytoband F
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    294 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1923417
 protein coding gene Chr5:124621099-124631649 (+)
129S1/SvImJ MGP_129S1SvImJ_G0030097
 protein coding gene Chr5:128311287-128321083 (+)
A/J MGP_AJ_G0030062
 protein coding gene Chr5:122957227-122965208 (+)
AKR/J MGP_AKRJ_G0029998
 protein coding gene Chr5:126926917-126934877 (+)
BALB/cJ MGP_BALBcJ_G0030073
 protein coding gene Chr5:124296564-124304530 (+)
C3H/HeJ MGP_C3HHeJ_G0029790
 protein coding gene Chr5:127537408-127545384 (+)
C57BL/6NJ MGP_C57BL6NJ_G0030526
 protein coding gene Chr5:133278897-133287685 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0027752
 protein coding gene Chr5:117483134-117490894 (+)
CAST/EiJ MGP_CASTEiJ_G0029200
 protein coding gene Chr5:126645290-126653243 (+)
CBA/J MGP_CBAJ_G0029760
 protein coding gene Chr5:138510254-138519453 (+)
DBA/2J MGP_DBA2J_G0029910
 protein coding gene Chr5:122976276-122986136 (+)
FVB/NJ MGP_FVBNJ_G0029866
 protein coding gene Chr5:122021727-122029975 (+)
LP/J MGP_LPJ_G0029999
 protein coding gene Chr5:128846606-128854576 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0029897
 protein coding gene Chr5:142077100-142085065 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0030567
 protein coding gene Chr5:126546981-126556134 (+)
PWK/PhJ MGP_PWKPhJ_G0028914
 protein coding gene Chr5:121800487-121808643 (+)
SPRET/EiJ MGP_SPRETEiJ_G0028751
 protein coding gene Chr5:124165874-124173808 (+)
WSB/EiJ MGP_WSBEiJ_G0029273
 protein coding gene Chr5:127230464-127240785 (+)



Homology
more
  • Human Ortholog
    SNRNP35, small nuclear ribonucleoprotein U11/U12 subunit 35
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    SNRNP35, small nuclear ribonucleoprotein U11/U12 subunit 35
  • Synonyms
    HM-1, HM1, U1SNRNPBP
  • Links
    NCBI Gene ID: 11066
    UniProt: Q16560

  • Chr Location
    12q24.31; chr12:123458088-123473154 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    11 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    20
  • GO References
    9
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    732
  • Tissues
    24
  • cDNA Data
    12
  • Literature Summary
    2
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000029402 Ensembl Gene Model | MGI Sequence Detail 7991 C57BL/6J ±  kb
transcript ENSMUST00000111453 Ensembl | MGI Sequence Detail 1181 Not Applicable  
polypeptide ENSMUSP00000107080 Ensembl | MGI Sequence Detail 244 Not Applicable  
For the selected sequence
Protein
Information
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  • UniProt
    2 Sequences
  • Protein Ontology
    PR:000015335 U11/U12 small nuclear ribonucleoprotein 35 kDa protein
    (term hierarchy)
  • InterPro Domains
    IPR012677 Nucleotide-binding alpha-beta plait domain superfamily
    IPR035979 RNA-binding domain superfamily
    IPR000504 RNA recognition motif domain
    IPR034146 snRNP35, RNA recognition motif
    IPR051183 U1 snRNP 70 kDa and U11/U12 snRNP 35 kDa
Molecular
Reagents
less
  • All nucleic 15
    cDNA 12
    Primer pair 2
    Other 1

    Microarray probesets 2
References
more
  • Summaries
    All 39
    Developmental Gene Expression 2
    Gene Ontology 9
    Phenotypes 11
  • Earliest
    J:134667 Roderick TH, et al., Two radiation-induced chromosomal inversions in mice (Mus musculus). Proc Natl Acad Sci U S A. 1970 Oct;67(2):961-7
  • Latest
    J:246582 Doktor TK, et al., RNA-sequencing of a mouse-model of spinal muscular atrophy reveals tissue-wide changes in splicing of U12-dependent introns. Nucleic Acids Res. 2017 Jan 09;45(1):395-416
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
03/18/2025
MGI 6.24 		The Jackson Laboratory