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Slc35d3
Gene Detail
Symbol

Name
ID
Slc35d3
solute carrier family 35, member D3
MGI:1923407
Synonyms
6230421J19Rik, Frcl1
Feature Type
protein coding gene
Genetic Map
Chromosome 10
9.12 cM, cytoband A2
Detailed Genetic Map ± 1 cM


Mapping data(3)
Sequence Map
Chr10:19847917-19851459 bp, - strand
From Ensembl annotation of GRCm38

  3543 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:19123  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

HCOP human homology predictions: SLC35D3
Gene Tree: Slc35d3

Human
homologs
SLC35D3, solute carrier family 35, member D3
Orthology source: HGNC, HomoloGene

IDs:
NCBI Gene ID: 340146
neXtProt AC: NX_Q5M8T2

Human Synonyms: FRCL1

Human Chr (Location): 6q23.3; chr6:136922241-136925660 (+)  GRCh38.p2

Mutations,
alleles, and
phenotypes
All mutations/alleles(3) : Spontaneous(1) Targeted(2)
Incidental mutations (data from Mutagenetix , APF )
 
Mice homozygous for a spontaneous mutation exhibit decreased platelet serotonin.
 
Interactions
Slc35d3 interacts with 168 markers (Mir7-1, Mir7-2, Mir7b, ...)
Gene Ontology
(GO)
classifications
Expression
Literature Summary: (2 records)
Data Summary: Results (7)    Tissues (2)    Images (5)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 7
cDNA source data(10)
Other mouse links: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(11) cDNA(10) Primer pair(1)
Microarray probesets(3)
Other database
links
Ensembl Gene Model ENSMUSG00000050473 (Evidence)
Entrez Gene 76157 (Evidence)
UniGene 74324
DFCI TC1585073
DoTS DT.87048520
NIA Mouse Gene Index U031585
Consensus CDS Project CCDS23719.1
International Mouse Phenotyping Consortium Status Slc35d3
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000050473 Ensembl Gene Model | MGI Sequence Detail 3543 C57BL/6J ±  kb
transcript ENSMUST00000059805 Ensembl | MGI Sequence Detail 2629 Not Applicable 
polypeptide ENSMUSP00000060589 Ensembl | MGI Sequence Detail 422 Not Applicable 

For the selected sequences
All sequences(19) RefSeq(4) UniProt(2)
Polymorphisms
SNPs within 2kb(31 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR004853 Sugar phosphate transporter domain
Protein Ontology PR:000015100 solute carrier family 35 member D3
References
(Earliest) J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
(Latest) J:211009 Zhang Z, et al., Mutation of SLC35D3 causes metabolic syndrome by impairing dopamine signaling in striatal D1 neurons. PLoS Genet. 2014 Feb;10(2):e1004124
All references(31)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
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last database update
08/25/2015
MGI 6.0
The Jackson Laboratory