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Stx16 Gene Detail
Summary
  • Symbol
    Stx16
  • Name
    syntaxin 16
  • Synonyms
    5430410K23Rik, 6330500A18Rik, SYN16
  • Feature Type
    protein coding gene
  • IDs
    MGI:1923396
    NCBI Gene: 228960
  • Alliance
    genome feature page
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr2:173918101-173941564 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 2, 97.85 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    421 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1923396
 protein coding gene Chr2:173918052-173941564 (+)
129S1/SvImJ ENSMUSG00200039251
 protein coding gene Chr2:170855163-170878622 (+)
A/J ENSMUSG00195023304
 protein coding gene Chr2:171183725-171207181 (+)
AKR/J ENSMUSG00220033674
 protein coding gene Chr2:170477991-170501481 (+)
BALB/cJ ENSMUSG00180032257
 protein coding gene Chr2:170616651-170640141 (+)
C3H/HeJ ENSMUSG00175037382
 protein coding gene Chr2:171388692-171412156 (+)
C57BL/6NJ ENSMUSG00215020316
 protein coding gene Chr2:170815917-170839383 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0024754
 protein coding gene Chr2:166052444-166075862 (+)
CAST/EiJ ENSTCUG00005008380
 protein coding gene Chr2:169719779-169743239 (+)
CBA/J ENSMUSG00210038130
 protein coding gene Chr2:171298703-171322190 (+)
DBA/2J ENSMUSG00185023788
 protein coding gene Chr2:171012508-171035972 (+)
FVB/NJ ENSMUSG00205014964
 protein coding gene Chr2:170069031-170092528 (+)
JF1/MsJ ENSUMUG00000036486
 protein coding gene Chr2:170704239-170727692 (+)
LP/J ENSMUSG00230011660
 protein coding gene Chr2:172591451-172614906 (+)
NOD/ShiLtJ ENSMUSG00190039126
 protein coding gene Chr2:170695854-170719344 (+)
NZO/HlLtJ ENSMUSG00225002377
 protein coding gene Chr2:180583523-180607016 (+)
PWK/PhJ ENSLUMG00010035490
 protein coding gene Chr2:170595991-170619404 (+)
SPRET/EiJ ENSMSPG00010022787
 protein coding gene Chr2:173383058-173404034 (+)
WSB/EiJ ENSIUOG00005022071
 protein coding gene Chr2:170438702-170462165 (+)



Homology
more
  • Human Ortholog
    STX16, syntaxin 16
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    STX16, syntaxin 16
  • Synonyms
    SYN-16, SYN16
  • Links
    NCBI Gene ID: 8675
    UniProt: O14662

  • Chr Location
    20q13.32; chr20:58651261-58679526 (+)  GRCh38
Human Diseases
more
  • Diseases
    1 with human STX16 associations

Human Disease Mouse Models
      
IDs
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    15 phenotypes from 2 alleles in 2 genetic backgrounds
    14 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice homozygous for a knock-out allele are viable and fertile and do not exhibit methylation abnormalities or develop a pseudohypoparathyroidism resistance phenotype.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    41
  • GO References
    12
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    672
  • Tissues
    45
  • cDNA Data
    81
  • Literature Summary
    4
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000027522 Ensembl Gene Model | MGI Sequence Detail 23464 C57BL/6J ±  kb
    transcript ENSMUST00000087908 Ensembl | MGI Sequence Detail 3865 Not Applicable  
    polypeptide ENSMUSP00000085218 Ensembl | MGI Sequence Detail 326 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 81
      cDNA 81
      Antibodies 1

      Microarray probesets 4
    Other
    Accession IDs
    less
    MGI:1914046, MGI:2139029, MGI:2139392
    References
    more
    • Summaries
      All 51
      Developmental Gene Expression 4
      Gene Ontology 12
      Phenotypes 14
    • Earliest
      J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
    • Latest
      J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    09/01/2026
    MGI 6.24     		The Jackson Laboratory